Assistant Professor of Neurology
Dr. Alosco completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus in neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. In 2015, Dr. Alosco was awarded a post-doctoral fellowship at the Boston University (BU) Alzheimer’s Disease (AD) Center (ADC) and BU CTE Center through the NIA-funded Alzheimer’s Disease Translational Research Training Program (T32AG036697). In 2016, Dr. Alosco transitioned to a National Research Service Award (NRSA) F32 from the National Institute of Neurological Disorders and Stroke to continue his advanced clinical research training at the BU ADC and BU CTE Center. In 2018, he became an Assistant Professor of Neurology at the Boston University School of Medicine.
CTE Center Role
Dr. Alosco conducts clinical interviews with family members and other caregivers of deceased athletes who donate their brains to our center. This history is used to conduct studies on risk factors and clinicopathological correlations of CTE and other neurodegenerative diseases. He is also involved in Dr. Stern’s ongoing studies that examine the clinical presentation of CTE, as well as potential in vivo biomarkers that may be able to detect CTE during life.
Dr. Alosco participates in weekly multidisciplinary diagnostic consensus conferences to assist with the clinical diagnoses for participants enrolled in the ADC Clinical Core Registry. He is also the ADC’s Clinical Core Associate Director.
Dr. Alosco’s research focuses on risk factors and biomarkers of neurodegenerative conditions, with a focus on AD and CTE. Dr. Alosco is particularly interested in the contribution of cerebrovascular disease to the clinical and neuropathological presentation of AD and CTE. He is additionally involved in research examining the relationship between exposure to repetitive head impacts and long-term neurological consequences. He is mentored at the BU AD and CTE Center by Robert A. Stern, Ph.D., and Ann C. McKee, M.D.
Dr. Alosco was the recipient of the American Psychological Association Early Graduate Student Research Award in 2012. He received the Kent State University David B. Smith Award in 2014, an award that provides recognition for the most outstanding graduate student at Kent State University. He also received the 2016-2017 BU ADC Pilot Grant. He serves as an ad-hoc reviewer for numerous journals, has accumulated >100 peer-reviewed publications, and has multiple book chapters. He is a member of the American Psychological Association and Massachusetts Neuropsychological Society.
- Alosco, M.L., Mez, J., Kowall, N.K., Stein, T.D., Goldstein, L.E., Cantu, R.C., Katz, D.I., Solomon, T.M., Kiernan, P.T., Murphy, L., Abdolmohammadi, B., Daneshvar, D., Montenigro, P.H., Nowinski, C.J., Stern, R.A., & McKee, A.C. (2017). Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy. The Journal of Neuropsychiatry and Clinical Neurosciences, 29, 6-12.
- Alosco, M.L., Tripodis, Y., Jarnagin, J., Baugh, C.M., Martin, B., Chaisson, C.E., Estochen, N., Son, L., Cantu, R.C., Jeromin, A., & Stern, R.A. (2017). Repetitive Head Impact Exposure and Later-Life Plasma Total Tau in Former NFL players. Alzheimer’s & Dementia: Diagnosis, Assessment and Disease Monitoring, 7, 33-40.
- Alosco, M.L.,* Duskin, J.,* Besser, L.M., Martin, B., Chaisson, C.E., Gunstad, J., Kowall, N.W., McKee, A.C., Stern, R.A., & Tripodis, Y. (2017). Modeling the Relationships Among Late-Life Body Mass Index, Cerebrovascular Disease, and Alzheimer’s Disease Neuropathology in an Autopsy Sample of 1,421 Subjects from the National Alzheimer’s Coordinating Center Data Set. Journal of Alzheimer’s Disease; 57:953-968
- *Shared first authorship
- Besser, L.M.,* Alosco, M.L.,* Ramirez Gomez, L., Zhou, X.H., McKee A.C., Stern, R.A., Gunstad, J., Schneider, J.A., Chui, H., & Kukull, W.A. (2016). Late-Life Vascular Risk Factors and Alzheimer Disease Neuropathology in Individuals with Normal Cognition. Journal of Neuropathology and Experimental Neurology, 75, 955-962.*Shared first authorship
- Alosco, M.L., Jarnagin, J., Tripodis, Y., Platt, M., Martin, B., Chaisson, C.E., Baugh, C.M., Fritts, N.G., Cantu, R.C., Stern, R.A. (2017). Olfactory Function and Associated Clinical Correlates in former NFL players. Journal of Neurotrauma, 34, 772-780.
- Cherry, J.D., Tripodis, Y., Alvarez, V.E., Huber, B., Kiernan, P.T., Daneshvar, D.H., Mez, J., Montenigro, P.H., Solomon, T.M., Alosco, M.L., Stern, R.A., McKee A.C., Stein, T.D. (2016). Microglial Neuroinflammation Contributes to Tau Accumulation in Chronic Traumatic Encephalopathy. Acta Neuropathol Commun, 4, 112.
- Chapman, K.R., Bing-Canar, H., Alosco, M.L., Steinberg, E., Martin, B., Chaisson, C., Kowall, N., Tripodis, Y., & Stern, R. (2016). Mini-Mental State Examination and Logical Memory scores for entry into Alzheimer trials. Alzheimer’s Research & Therapy, 8:9.
- Montenigro, P.H., Alosco, M.L., Martin, B.M., Daneshvar, D.H., Mez, J., Chaisson, C., Nowinski, C.J., Au, R., McKee, A.C., Cantu, R.C., McClean, M.D., Stern, R.A., & Tripodis, Y. (2017). Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players. Journal of Neurotrauma, 34, 328-340.
- Stern, R.A., Seichepine, D., Tschoe, C., Fritts, N.G., Alosco, M.L., Berkowitz, O., Burke, P., Howland, J., Olshaker, J., Cantu, R.C., Baugh, C.M., & Holsapple, J.W. (2017). Concussion Care Practices and Utilization of Evidence-Based Guidelines in the Evaluation and Management of Concussion: A Survey of New England Emergency Departments. Journal of Neurotrauma, 34,861-868.
- Alosco M.L., Jarnagin, J., Tripodis, Y., Martin, B., Chaisson, C., Baugh, C.M., Torres, A., Nowinski, C.J., Cantu, R., & Stern R.A. (2017). Utility of providing a concussion definition in the assessment of concussion history in former NFL players. Brain Injury, DOI: 10.1080/02699052.2017.1294709
- Clinical Research