The VA-BU-CLF Brain Bank is the largest tissue repository in the world focused on traumatic brain injury (TBI) and CTE. The VA-BU-CLF Brain Bank research team conducts cutting edge research on Chronic Traumatic Encephalopathy (CTE) and mild traumatic brain injury. The brain bank contains more than 425 brains, including over 270 brains that have been diagnosed with CTE using the recently defined NINDS criteria for the diagnosis of CTE (6). Dr. McKee and her team of neuropathologists and other investigators have published a large number of studies focused on CTE (see below).
The VA-BU-CLF brain bank:
Collects central nervous system tissue samples (brain, spinal cord and eyes) from deceased athletes to better understand the effects of trauma on the human nervous system.
Reports findings to caregivers in a timely fashion
Stores and distributes optimally prepared tissue to qualified researchers around the world
Shares data and other findings with other researchers
The VA-BU-CLF research team is focused on developing:
- A diagnostic test for CTE in living persons
- Genetic risk factors
- Environmental risk factors
- The importance of age at first exposure
- The roll of length of playing career
- Treatment for CTE
The identity of donors is confidential and protected by both IRB rules and HIPAA laws. However, many donors have chosen to allow the CTE Center to release their names to draw attention to this important work.
For urgent brain donation matters, please call the BU CTE Center's 24/7 voicemail/pager at 617-992-0615.
For general brain donation inquiries, please contact our research assistants Bobby Abdolmohammadi by phone at 617-414-1184 or Laney Evers by phone at 617-414-1187.
Similar to organ donation, the pledge of one's brain is a precious gesture that helps others in a truly impactful way. To learn more about how you can pledge your brain to the VA-BU-CLF Brain Bank, click here.
“One of the most profound actions I can take personally is to donate my brain to help ensure the safety and welfare of active, retired, and future athletes for decades to come.”
— Sean Morey Retired NFL Player, SLI Brain Donor
“It’s something that we don’t like to talk about as players because I think we’re afraid of what could happen to us years from now. But what they were finding at Boston University was pretty eye-opening, so I wanted to do my part and help out. I think all of us as players should try to do whatever we can to help improve player safety for the guys who come after us.”
— Matt Birk NFL All-Pro Center
All publication of findings are de-identified (without name and identifiable details) unless the CTE Center has received permission from the family to publicize the subject’s participation.Family members of deceased athletes may donate their loved one’s brain and spinal cord after their death to the VA-BU-CLF Brain Bank to be examined neuropathologically for evidence of CTE or other disorders of the central nervous system. The family member(s) will be interviewed to better understand the recently deceased history: including athletic and concussion history, educational and occupational history, medical history, and history of cognitive, behavioral, and mood symptoms.
To donate a brain,
please contact our our research assistants Bobby Abdolmohammadi by phone at 617-414-1184 or Laney Evers by phone at 617-414-1187. You can reach both Bobby and Laney on our 24/7 voicemail/pager at 617-992-0615.
Frequently Asked Questions about Brain Donation
Why is brain tissue donation important?
The purpose of the research is to help understand the long-term effects of previous brain injuries, including any association with chronic traumatic encephalopathy (CTE). This donation process is an opportunity for individuals to help further research and help protect future generations. Participation will help researchers to better understand CTE, including its neuropathology, clinical presentation and course, and environmental and genetic risk factors.
Who can give consent for brain tissue donation?
The legally authorized representative (usually, the next of kin) may give consent to donate brain and spinal cord tissue following the death of a donor.
Who handles organizing the tissue donation?
A full-time brain donation coordinator is available 24/7, 365 days per year to arrange the tissue collecting by a local diener near the locality where the donor has died. All costs for the extraction are paid by the VA-BU-SLI Brain Bank. The donation process is a time-sensitive matter; for urgent brain donation matters, please call the BU CTE Center 24/7 voice mail/pager at 617-992-0615.
Is there any cost associated with this study?
There are no costs for participating in this research study. The study will pay for all expenses involved with brain and spinal cord donation. Please note that funeral expenses remain the responsibility of the family.
What is the role of the next of kin in the donation process?
The next of kin is required to complete consent forms authorizing brain, spinal cord, and CSF and/or plasma donation. These will be faxed or emailed by the brain donation coordinator. Once completed, the donor’s next of kin is required to fax and/or email the signed consent forms back to the brain donation coordinator. One copy is retained by the VA-BU-SLI Brain Bank, and another copy is faxed to the local diener.
What happens to the body?
The autopsy procedure does not interfere with the events associated with the funeral. No disfigurement occurs as a result of this procedure. The family can plan an open casket or other traditional funeral arrangements and the donation process will be undetectable. In addition, we will do our best not to interfere with any arrangements the family might have.
What is the role of family members after a donation has been made?
One important goal of the research is to better understand the clinical presentations of CTE. In order to do this, we try to gather as much relevant information about our donors during their life as possible. Family members help by supplying relevant information to a designated clinician.