Clinical Trials & Translational Studies in Scleroderma & PAH

For general information on studies, or if you are not sure which one is suitable, contact Nina Kishore at 617.414.2509 or nkishore@bu.edu

Actively Recruiting Clinical Trials

Study Name

Indication

Principal Investigator

Study Contact

Email/Phone

The Scleroderma Clinical Repository SSc Robert Lafyatis, MD Eric Stratton eas@bu.edu

617.414.2507

Rilonacept- Randomized, Double-Blind,
Placebo-Controlled Trial of IL1-TRAP –
A Phase I/II Biomarker Trial
Diffuse SSc Robert Lafyatis, MD Jessica Ziemek jziemek@bu.edu

617.638.5383

Quantification of Septal Thickening in
Scleroderma Patients Utilizing Hyperpolarized
129Xe MRI
SSc with ILD Robert Lafyatis, MD Fei-Ying Cheong fycheong@bu.edu

617.638.4344

A Randomized, Double-Blind, Placebo-
Controlled, Phase II Multi-Center Trial of a
Monoclonal Antibody to CD20 (Rituxamab)
For the Treatment of Systemic Sclerosis-
Associated Pulmonary Arterial Hypertension
Harrison Farber, MD

Robert Simms, MD

Eric Stratton

Fei-Ying Cheong

eas@bu.edu
SYMPHONY- A Multi-center, Open Label,
Single-arm, Phase 3b Study of
Macitentan in Patients with
Pulmonary Arterial Hypertension
to psychometrically validate the
PAH-SYMPACT instrument
PAH Harrison Farber, MD Kim Finch kimtobin@bu.edu

617.638.4475

MELODY-1 Study – A prospective, multicenter, double-blind, randomized, placebo-controlled, parallel-group, 12-week study to evaluate the safety and tolerability of macitentan in subjects with combined pre- and post-capillary pulmonary hypertension (CpcPH) due to left ventricular dysfunction. PAH Harrison Farber, MD Fei-Ying Cheong fycheong@bu.edu

617.638.4344

LARIAT – A dose-ranging study of the efficacy and safety of Bardoxolone Methyl in patients with PAH PAH Harrison Farber, MD Kim Finch kimtobin@bu.edu

617.638.4475

SPIN Study:  The Scleroderma patient-centered intervention network cohort SSc Robert Simms, MD Fei-Ying Cheong fycheong@bu.edu

617.638.4344

Actively Recruiting Translational Studies

Fibroblast and Immune Cell
Culture From Skin
Diffuse SSc Robert Lafyatis, MD Jessica Ziemek jziemek@bu.edu

617.638.5383

CORT Biomarker Study SSc Robert Lafyatis, MD Eric Stratton eas@bu.edu

 

 

 

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