BU-BRIDGE Clinical and Translational Science Institute
The Boston University Clinical and Translational Science (BU-BRIDGE) Institute
integrates, connects, and expands research and programs across traditional
academic departments and schools. The institute acts as a bridge between
disciplines to facilitate interactions by incorporating multiple key programs
that support the university-wide commitment to a home for translational
research. An NIH-funded clinical and translational science award funds the
Institute to build on existing strengths to create an environment linking
faculty members, trainees and university programs. The ultimate goal is to
speed the translation of innovations in medical science in order to improve
maintenance of health and diagnosis and treatment of diseases and share these
innovations with other University-based Clinical and Translational Science
Awards (CTSAs). The BU-BRIDGE environment also supports the bi-directional
development and translation of ideas that begin in the clinic to the BU
scientific community and back to identify new ways to improve health and
delivery of health care services. Moreover, the Institute significantly
enhances existing partnerships with Boston's community health centers,
transforming the conduct of clinical and translational research by infusing it
with community-based perspectives and needs.
Introduction to the General Clinical Research Unit (GCRU)
The BUMC General
Clinical Research Unit supports research services, specialized
laboratories and a clinical research-training program for all BU staff
including investigators in Medicine, Surgery, Psychiatry, Behavioral Sciences,
Dentistry and Public Health.
The facility provides investigators in medicine and dentistry with the
following: the ability to conduct pharmacokinetic studies in a controlled
environment in both adult and pediatric inpatients and outpatients the
resources for timed collection of specimens and repetitive tests (e.g.
polysomnography, stress tests, bone density, etc.) the expertise to conduct
esoteric laboratory testing a bioinformatics core with professionals to assist
with statistical design, data management and analysis a private environment to
explore patterns of behavior the location for education of future physicians,
scientists and nutritionists in patient oriented research.
The Core Assay Laboratory is a part of the
General Clinical Research Unit and is accessed through an application
to the GCRU.
See General Clinical Research Unit under
Investigators. The assays performed are part of a clinical research protocol
that is approved by the IRB and the Clinical Research Resources Advisory
Committee (CRRAC).
Current assays included but not limited to:
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25(OH)D
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PTH
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Osteocalcin
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CTX
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CRP
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TSH
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Insulin
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Cortisol
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Glucagon
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Leptin
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TNF_alpha
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C-peptide
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Testosterone (total)
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Estradiol
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DHT
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SHBG
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LH
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FSH
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PSA
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Fat tissue D2 and D3
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Fat tissue 25D2 and 25D3
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Serum D2 and D#
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Serum 25D2 and D3
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1,25(OH)2D
Investigators are often, but not always, asked to cost share through the
purchase of assay kits. Please contact Tai Chen
for detailed information.
Contact
Tai Chen, Ph.D, Director
Phone: 617 -638-4543
Fax: 617-638-8898
Location
Fuller Building
M-1022, 10th Floor
85 East Newton Street
Boston, MA 02118
Monday - Friday
9:00 AM to 5:00 PM
Instruments/Services – N/A
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