Chemistry Courses

Graduate courses are listed below.

Undergraduate Courses

Courses marked with a (+) satisfy natural science divisional studies requirements.

+CAS CH 101, +CAS CH 102: General Chemistry

First semester prereq: two years of high school algebra. Second semester prereq: CH 101. For science concentrators who require a two-semester general chemistry course. Stoichiometry, gases, liquids, solids, solutions, equilibrium, thermodynamics, electrochemistry, atomic structure and bonding, kinetics, and selected chemical systems. Laboratory exercises include qualitative analysis. Three hours lecture, one hour discussion, one hour lab lecture, and three hours lab. Tullius, Coker, Dill, Grinstaff, Keyes, Prock, Golger, assistants. 4 cr each, both courses 1st & 2nd sem. (NS) (lab)

Course Links
CH 101 (Fall): http://quantum.bu.edu/courses/ch101
CH 102 (Spring): http://quantum.bu.edu/courses/ch102

+CAS CH 109, +CAS CH 110: General and Quantitative Analytical Chemistry

Prereq: one year of high school chemistry, two years of high school algebra. Two-semester sequence for students concentrating in the sciences, especially for those considering a chemistry or biochemistry-molecular biology major but who do not enroll in CH 111/112. Stoichiometry, acids, bases, liquids, solids, solutions, equilibria, thermodynamics, kinetics, electrochemistry, atomic structure, bonding, and selected chemical systems. Correlated laboratory experiments emphasizing quantitative analysis. Three hours lecture, one hour discussion, one hour lab lecture; four hours lab in each semester. Georgiadis, Elliott, Staff. 4 cr each, 1st & 2nd sem. (NS) (lab)

Syllabus
CH 109 (Fall): CH 109 Fall09 Syllabus
CH 109 (Fall): CH 109 Fall09 Lab Syllabus
CH 110 (Spring): CH 110 Sprg09 Syllabus
CH 110 (Spring): CH 110 Sprg09 Syllabus

+CAS CH 111, +CAS CH 112: Intensive General and Quantitative Analytical Chemistry

First semester prereq: one year of high school chemistry, two years of high school algebra, and departmental chemistry placement examination. Coreq: CAS MA 123, MA 127, MA 129, or advanced placement in calculus. Second semester prereq: CAS CH 111. Intensive two-semester sequence for well-prepared students concentrating in chemistry or other sciences. Priority given to chemistry concentrators. Brief review of stoichiometry, gas laws; extensive consideration of equilibrium, thermodynamics, atomic and molecular structure, kinetics; application of principles to selected elements and compounds. Correlated laboratory experiments emphasizing applications of quantitative analysis. Three hours lecture, one hour discussion, one hour lab lecture, four hours lab in each semester. Straub, Harris, Murphy, assistants. 4 cr each, 1st & 2nd sem. (NS) (lab)

+CAS CH 131: General Chemistry for the Engineering Sciences

Coreq: CAS MA 123. A one-semester, terminal general chemistry course for students who do not require a two-semester sequence. Stoichiometry, atomic and molecular structure, bonding, chemistry of solid state, chemical thermodynamics, and equilibrium. Three hours lecture, one hour discussion, three and a half hours lab. Rubio, Ziegler, assistants. 4 cr, 1st sem. (NS) (lab)

+CAS CH 171: Principles of General Chemistry

Introduction to chemistry: separation and purification of matter, atomic theory, structure of atoms, molecules and chemical bonding, chemical formulas, equations, stoichiometry; water, solutions, concentration, acids, bases, pH and buffers; gases; reaction kinetics and equilibrium, and radioactivity. Three hours lecture, one hour discussion, one hour prelab lecture, and three hours lab. Kyte, Staff. 4 cr, 1st sem. (NS) (lab)

Syllabus
CH 171 Fall09 Syllabus
CH 171 Fall09 Lab Syllabus

+CAS CH 172: Principles of Organic and Biochemistry

Prereq: CAS CH 171 or CH 101, 102. Organic chemistry: structure, stereochemistry, and reactions of carbon compounds; emphasis on compounds of biochemical interest: polysaccharides, lipids, nucleic acids, and proteins.  Biochemistry: structure and function of molecules of biological importance; metabolism of carbohydrates, lipids, and amino acids.  Three hours lecture, one hour discussion, one hour prelab lecture, and three hours lab. 4 cr, 2nd sem. (NS) (lab) CAS CH 171 combined with CAS CH 172 are intended as a terminal sequence.

CAS CH 174: Principles of Organic Chemistry

Prereq: CAS CH 171 or CH 101, 102. Structure, stereochemistry, functional groups, and reactions of carbon-containing compounds; spectroscopic techniques; emphasis on compounds and molecules of biochemical interest.  Three hours lecture, one hour discussion, one hour prelab lecture, and three hours lab. 4cr, 2nd sem.

CAS CH 181, CAS CH 182: Intensive General and Quantitative Analytical Chemistry

For seven-year medical students only. Lectures shared with CH 111, 112. See description for CH 111, 112. Three hours lecture, one hour discussion, four hours lab. 4 cr each, 1st & 2nd sem.

CAS CH 191, CAS CH 192: Undergraduate Research in Chemistry I

Prereq: freshman standing; consent of instructor. Experimental or theoretical investigation of problems including the use of the literature. Attendance at weekly research seminars and the writing of a report at the end of each semester required. Application must be made through the Department of Chemistry office during the first two weeks of the semester. Variable cr, 1st & 2nd sem.

CAS CH 201: Quantitative Analytical Chemistry Laboratory

Prereq: CAS CH 102. Applications of quantitative analysis. Equivalent to the laboratory part of CAS CH 112. One hour lecture, four hours lab. 2 cr, 2nd sem.

CAS CH 203, CAS CH 204: Organic Chemistry

First semester prereq: CAS CH 102, CH 110, or 112. Second semester prereq: CAS CH 203. Fundamentals of contemporary organic chemistry, including electronic structure, stereochemistry, and reactions of important functional groups. Laboratory includes extraction, distillation, and chromatography. Three hours lecture, one hour discussion, one hour prelab lecture, three-and-a-half hours lab on alternate weeks. 4 cr each, CH 203 1st sem; CH 204 2nd sem.

CAS CH 211, CAS CH 212: Intensive Organic Chemistry

First semester prereq: CAS CH 102, CH 110, or CH 112. Second semester prereq: CAS CH 211. Recommended for Chemistry concentrators. Organic compounds and their reactions; functional groups, stereochemistry, synthesis, reaction mechanisms, and laboratory methods including qualitative organic analysis. Industrial applications and relevance to biological systems. Three hours lecture, one hour discussion, one hour prelab lecture, four hours lab. 4 cr each, 1st & 2nd sem.

CAS CH 214: Organic Chemistry with Qualitative Analysis

Prereq: CAS CH 203. Lecture and discussion shared with CAS CH 204. Three hours lecture, one hour discussion weekly, one hour prelab lecture, four hours lab. 4 cr, 2nd sem.

CAS CH 220: Organic Chemistry Laboratory with Qualitative Analysis,

Prereq: CAS CH 204. Laboratory methods in organic chemistry including multistep synthesis, organic qualitative analysis, and instrumental analysis. Equivalent to the laboratory part of CAS CH 212 or CH 214. One hour lecture, four hours lab. 2 cr, 2nd sem.

CAS CH 232: Inorganic Chemistry

Prereq: CAS CH 102, CH 110, or CH 112; coreq: CAS CH 204, CH 212, or CH 214. The relation of atomic and molecular structure to chemical properties. Bronsted and Lewis acid/base behavior; redox reactions; bonding and reactions of main group elements; d-metal complexes, including bonding, spectra, and reaction mechanisms; and organometallic chemistry. Three hours lecture, one hour discussion, four hours lab. 4 cr, 2nd sem.

CAS CH 273: Principles of Biochemistry

Prereq: CAS CH 174. Biomolecules in aqueous systems. Composition, structure, and function of proteins, nucleic acids, and polysaccharides. Information transfer from DNA to RNA and proteins. Bioenergetic principles in glycolysis, oxidative energy metabolism, and selected biosynthetic paths. Applications to medicine, nutrition, and biotechnology. Three hours lecture, one hour discussion. 4 cr, 1st sem. This course is not recommended for students who have taken 1 year of General Chemistry and 1 year of Organic Chemistry. See CAS CH 421.

CAS CH 291, CAS CH 292: Undergraduate Research in Chemistry II

Prereq: sophomore standing and consent of instructor. See CAS CH 191, 192 for description. Variable cr, 1st & 2nd sem.

CAS CH 301: Chemical Synthesis and Analysis

Prereq: CAS CH 212, CH 214 or CH 220. Combined lecture/ laboratory course that introduces fundamental methods of synthesis and analysis current in chemical research. Applications include topics in organocatalysis, asymmetric synthesis and organometallic chemistry, and spectroscopy. Eight hours lab plus three hours lecture. 4 cr, 1st sem.

CAS CH 351: Physical Chemistry I

Prereq: CAS CH 102, CH 110, or CH 112 and CAS PY 212 and CAS MA 124; coreq: CAS MA 225. Quantum Theory, atomic and molecular structure, molecular spectroscopy, statistical mechanics, solid state chemistry. Three hours lecture, one hour discussion. 4 cr, 1st sem.

CAS CH 352: Physical Chemistry II

Prereq: CAS CH 102, CH 110, or CH 112; CAS PY 212 and CAS MA 124; coreq: CAS MA 225. Thermodynamics, equilibrium, chemical kinetics. Applications include electrochemistry, phase transitions, catalysis, aqueous solutions, and polymers. Three hours lecture, one hour discussion. 4 cr, 2nd sem.

CAS CH 354: Physical Chemistry Laboratory

Prereq: CAS CH 351; coreq: CAS CH 352. Experiments in thermodynamics, electrochemistry, chemical equilibrium, chemical kinetics, and spectroscopy. Applications and principles of electronics and instrumental design and applications of computers. Statistics and error analysis of laboratory data. Four hours lab plus prelab lecture. 4 cr, 2nd sem.

CAS CH 391, CAS CH 392: Undergraduate Research in Chemistry III

Prereq: junior standing and consent of instructor. See CAS CH 191, 192 for description. Variable cr, 1st & 2nd sem.

CAS CH 401, CAS CH 402: Senior Independent Work

Prereq: approval of the Honors Committee. Experimental or theoretical investigation of problems including search and use of literature. Weekly research seminars, periodic written reports, and oral exam and thesis at the end of the second semester. Applications for independent work for distinction must be made through the CAS Academic Advising office. 4 cr each, 1st & 2nd sem. An oral presentation at the Undergraduate Research Symposium in the end of the spring semester is required to successfully complete this course.

CAS CH 421: Biochemistry I

Prereq: CAS CH 204, CH 212, or CH 214. Introductory biochemistry. Protein structure and folding, enzyme mechanisms, kinetics, and allostery; nucleic acid structure; lipids and membrane structure; bioenergetics; vitamins and coenzymes; introduction to intermediary metabolism. Three hours lecture, one hour discussion, four hours lab. 4 cr, 1st sem.

CAS CH 422: Biochemistry II

Prereq: CAS CH 421 or equivalent. Polysaccarides, energy storage and recognition; intermediary metabolism; lipid and isoprene metabolism; nitrogen metabolism; nucleotide metabolism, macromolecular biosynthesis with emphasis on specificity and fidelity in the mechanisms of RNA, DNA, and protein synthesis. Three hours lecture, one hour discussion, four hours lab. 4 cr, 2nd sem.

CAS CH 445: Transition Metal Chemistry

Not offered 2009/2010

CAS CH 458: Chemical Kinetics and Dynamics

Not offered 2009/2010

CAS CH 491, CAS CH 492: Undergraduate Research in Chemistry IV

Prereq: senior standing and consent of instructor. See CAS CH 191, 192 for description. Variable cr, 1st & 2nd sem. An oral presentation at the Undergraduate Research Symposium at the end of the spring semester is required to complete this course.

CAS CH 525: Physical Biochemistry

Pre- or coreq: CAS BI/CH 421; CAS MA 121 or MA 123; CAS PY 106 or PY 212. Cannot be taken for credit as an advanced course for chemistry majors or in addition to CAS CH 351, 352. Introduction to physical chemical principles with particular application to topics in biochemistry, solution and solid phase chemistry of biomolecules as studied by equilibrium, hydrodynamics, and spectroscopic/quantum mechanical methods. Three hours lecture, one hour discussion. 4 cr, 2nd sem.

CAS CH 527, 528 Biochemistry Laboratory I, II

Prereq: CAS CH 204 or CH 212 or CH 214. Coreq: GMS BI 555, 556. For students enrolled concurrently in GMS BI 555, 556. First semester emphasizes the purification and characterization of proteins and DNA. Second semester emphasizes protein, carbohydrate, and lipid chemistry. Development and use of modern instrumentation and techniques. Same as CAS BI 527, 528 and the laboratory portion of CAS CH/BI 421, 422. Four hours lab, one hour discussion. 2 cr each, 1st & 2nd sem.

Graduate Courses

A wide variety of graduate courses are offered, including basic courses and advanced courses (which are italicized below):

GRS CH 525 – Physical Biochemistry

Prereq: CAS BI/CH 422, MA 121 or MA 123, PY 106 or PY 212. Introduction to physical chemical principles, with particular application to topics in biochemistry, solution and solid phase chemistry of biomolecules as studied by equilibrium, hydrodynamic, and spectroscopic/quantum mechanical methods. Three hours lecture, one hour discussion. 4 cr, 2nd sem. Does not qualify for credit in graduate degree programs in Chemistry.

GRS CH 541 – Natural Products Chemistry

Prereq: CAS CH 212 and consent of instructor. Chemical and biosynthetic pathways leading to important natural products derived from fatty acids, terpenes, amino acids, poluketides, shikimic acid, and other biosynthetic intermediates. Three hours lecture. 4 cr, 1st sem. Not offered 2010/2011.

GRS CH 551 – Chemical Dynamics

Prereq: CAS CH 352 or equivalent. Reaction kinetics and mechanisms. Experimental methods including fast techniques. Theories of reaction dynamics. Mechanisms of electron transfer, energy transfer, catalysis, enzyme reactions. Photochemistry, photophysics, radiation chemistry, free radical reactions. Three hours lecture. 4 cr, either sem. Not offered 2010/2011.

GRS CH 552 – Electrochemistry

Prereq: MA 226, CH 352, or equivalent. Electrochemistry applied to heterogeneous and homogeneous processes, with emphasis on cyclic voltammetry and AC polarography. Use of the Laplace transforms and infinite difference methods. Students explore the kinetics and thermodynamics of fast reactions by computer simulation of electrochemical data. Three hours lecture. 4 cr, either sem. Not offered 2010/2011.

GRS CH 533/534 – Molecular Structure Determination

Prereq: CAS CH 352 or equivalent. Principles of x-ray crystallography. Vectors, reciprocal space, and symmetry elements. Fourier and Patterson functions; statistical methods and inequalities as applied to x-ray crystallography. Refinement procedures. Electron and neutron diffraction. Three hours lecture. 4 cr each, 1st & 2nd sem. Not offered 2010/2011.

GRS CH 612 – Separation Methods in Chemistry and Biochemistry

Prereq: CAS CH 301 or consent of instructor. Methods of chemical separation in chemistry and biochemistry, including gas, high performance liquid, thin layer, ion exchange, size exclusion (gel filtration), affinity chromatography, and electrophoresis. Theory of chromatography, instrumentation, and experimental considerations. Preparative and countercurrent techniques. Three hours lecture. 4 cr, 1st sem. Not offered 2010/2011.

GRS CH 621 – Biochemistry I

Prereq: CAS CH 204, CH 212, or equivalent; graduate status. Introductory biochemistry. Protein structure and folding enzyme mechanisms, kinetics, and allostery; nucleic acid structure; lipids and membrane structure; bioenergetics; vitamins and coenzymes; introduction to intermediary metabolism. Three hours lecture, 4 hours laboratory, 2 hours discussion. Same as GRS BI 621. Lecture and laboratory meet with CAS BI/CH 421. Liu, Tolan. 4 cr, 1st sem.

GRS CH 622 – Biochemistry II

Prereq: GRS CH 621 or equivalent. Polysaccharides, energy storage and recognition; intermediary metabolism; lipid and isoprene metabolism; nitrogen metabolism; nucleotide metabolism; macromolecular biosynthesis with emphasis on metabolism; nucleotide metabolism; macromolecular biosynthesis with emphasis on specificity and fidelity in the mechanisms of RNA, DNA, and proteins synthesis. Three hours lecture, 4 hours laboratory, 2 hours discussion. Same as GRS BI 622. Lecture and laboratory meet with CAS BI/CH 422. Kornberg. 4 cr, 2nd sem.

GRS CH 625 – Enzymology

Prereq: CAS CH421 or equivalent. Covers enzyme structure-function relationships. A tool-box of methods is presented, including kinetics (steady state and pre-steady state methods), isotope effects, stereo-chemical methods, site-directed mutagenisis, methods to replace natural with unnatural amino acids, mechanism based inhibitors. Three hours lecture. Liu. 4 cr, 2nd sem.

GRS CH 626 – Epigenetics

Surveys Protein post-translational modifications and DNA/RNA processing, including mechanistic enzymology of protein and DNA modifications, signal transduction induced by the modifications, and related practical applications. Liu. 4 cr. Not offered 2010/2011.

GRS CH 631 – Electronic Structure and Bonding

Prereq: CAS CH 232, or equivalent, and consent of instructor. Chemistry of selected main group elements; aspects of coordination chemistry, including stereochemistry, stability of complexes, bonding, electronic spectra, magnetic properties, kinetics and mechanisms of substitution, rearrangement and redox reactions; chemistry of selected transition elements. Three hours lecture. Doerrer. 4 cr, 1st sem. M/W/F 8am – 9am.

GRS CH 632 – Inorganic Reaction Mechanisms

The mechanistic study of ligand substitution and electron transfer processes in coordination compounds is discussed in the context of basic molecular orbital theory. The connections between small molecule inorganic and biological macromolecular, metal-catalyzed processes are presented. Not offered 2010/2011.

GRS CH 633 – Physical Methods for Inorganic and Bioinorganic Chemistry

The basis for this course is a discussion of the physical techniques for the assessment of structural, magnetic and redox-active properties of transitional metal complexes. Techniques discussed include: x-ray crystallography, x-ray absorption, vibrational, NMR, EPR and Mossbauer spectroscopies, and electrochemistry. Not offered 2010/2011.

GRS CH 634 – Metallobiochemistry

Prereq: CAS CH 232 & CAS CH 421 or equivalent, or consent of instructor. The roles of transition metals in biology are assessed by review of the structural, spectroscopic, and genetic aspects of metallobiochemistry. Metal import and trafficking; cofactor biogenesis; biocatalytic transformations in biochemistry; reactive oxygen species; the inorganic basis of life. Three hours lecture. Elliott. 4 cr, 1st sem. W/F 2pm – 3:30pm.

GRS CH 641 – Physical Organic Chemistry

Prereq: CAS CH 352; coreq: GRS CH 651, or consent of instructor. Physical fundamentals of organic chemistry; thermodynamics, kinetics, molecular orbital theory, theory of concerted reactions; isotope effects, aromaticity, linear free energy relationships, acidity functions, photo- and free-radical chemistry. Three hours lecture. Jasti. 4 cr, 1st sem. T/TH 11am – 12:30pm.

GRS CH 642 – Organic Reaction Mechanisms

Prereq: CAS CH 212, or consent of instructor. Fundamentals of organic reaction mechanisms; techniques used to study reaction mechanisms; reactive intermediates: carbonium ions, radicals, carbenes, nitrenes; acid/base catalysis, reactions for the carbonyl group, cycloaddition, nucleophilic displacement reactions, and redox chemistry. Four hours lecture. Stephenson. 4 cr, 1st sem. M/W 9am – 11am.

GRS CH 643 – Synthetic Methods in Organic Chemistry

Prereq: GRS CH 641 and CH 642. Organic synthetic strategies for total synthesis. Various approaches for organic molecules whose synthesis constitutes major contributions to organic chemistry. Three hours lecture. Panek. 4 cr, 2nd sem.

GRS CH 644 – Medicinal Chemistry

Prereq: CAS CH 212 or equivalent and consent of instructor. Medicinal chemistry; synthetic organic chemistry and pharmacology as applied to development, testing, and production of medically useful agents. Lectures and discussions by research chemists affiliated with leading pharmaceutical companies. A research paper is required. Three hours lecture. 4 cr, 2nd sem. Not offered 2010/2011.

GRS CH 645 – Transition Metal Chemistry

Introduction to the concepts of transition metal-mediated reactions and mechanisms, including electronic structure and properties, reaction mechanisms, kinetics, organometallic compounds, catalytic reactions, and aspects of asymmetric catalysis. Three hours lecture. 4 cr, 1st sem. Not offered 2010/2011.

GRS CH 651/652 – Molecular Quantum Mechanics

Prereq: CAS CH 351, CH 352, or equivalent. Suggested coreq: GRS CH 654. Introduction to quantum theory, atomic and molecular structure, spectroscopy. The chemical bond; Born-Oppenheimer approximation; electronic, vibrational, and rotational motion in molecules. NMR, ESR, microwave, IR, raman, visible, UV spectroscopy, computational ab initio methods for analyzing molecular structure and spectroscopy. Three hours lecture, two hours discussion. Wang, Ziegler. 4 cr, 1st & 2nd sem.

GRS CH 653 – Molecular Spectroscopy

Prereq: GRS CH 652 or equivalent. Theory of electromagnetic radiation-matter interactions; linear and nonlinear molecular spectroscopy, time and frequency domain spectroscopic techniques; molecular responses and dielectric relaxation processes; theory of NMR, ESR, microwave, IR, Raman, visible, and UV spectroscopies; computational methods. 4 cr, either sem. Not offered 2010/2011.

GRS CH 654 – Math Methods of Chemical Physics

Prereq: consent of instructor. Vector calculus with applications; Fourier series and Fourier integral with applications, and function of a complex variable with applications; also Green’s function methods, theory of linear vector spaces, and solutions of eigen function problems. Same as CAS PY 355, with extra discussion. 4 cr, either sem. Not offered 2010/2011.

GRS CH 655 – Statistical Mechanics I

Prereq: CAS CH 352 or equivalent. Fundamental principles; phase transitions; classical applications; time-dependent phenomena; scattering, spectroscopy, and time-correlation functions. Introduction to numerical methods of differentiation, integration, linear algebra, and solution of differential equations. Computational methods for Molecular Dynamics and Monte Carlo simulation of many-body systems. Three hours lecture. Reinhard. 4 cr, 1st sem. T/TH 9:30am – 11am.

GRS CH 656 – Statistical Mechanics II

Prereq: GRS CH 655 or equivalent. Selected advanced topics may include theories of liquids, free energy perturbation theory, phase transitions, Ising model, Zimm-Bragg model of coil-to-helix transition; irreversible thermodynamics, scattering, linear response theory, time correlation functions, transport, models of diffusion, chemical reaction rate theory, and spectroscopy. Ziegler. 4 cr, 2nd sem.

GRS CH 658 – Chemical Kinetics and Dynamics

Chemical kinetics and reaction dynamics. Rate theory. Theoretical models of reaction dynamics: transition state theory, collision theory, statistical methods. Transport theory. Modern experimental approaches. Photochemical and photophysical dynamics, energy transfer, condensed phase and atmospheric reaction processes. Straub. 4 cr, 2nd sem.

GRS CH 699 – Teaching College Chemistry

The goals, contents, and methods of instruction in chemistry. General teaching-learning issues. Required of all teaching fellows. Instructors vary. 2 cr, 1st and 2nd sem.

GRS CH 721 – Protein Structure Determination

Prereq: GRS CH 621 or equivalent (or consent of instructor). Theoretical and practical concepts underlying the determination of macromolecular structure, including: crystallization, crystal diffraction, space-group determination, solution of the phase problem, fourier-transform methods, structure refinement, and analysis. Three hours lecture. Whitty. 4 cr, 2nd sem.

GRS CH 722 – Protein Chemistry

Prereq: GRS CH 621 or equivalent. Methods for determining the structure of noncrystalline proteins, including protein sequence analysis, chemical modification, NMR spectroscopy and site-specific mutagenesis; case studies of the structure and function of selected proteins. Three hours lecture. Allen. 4 cr, 1st sem. T/TH 11am – 12:30pm.

GRS CH 723 – Physical Chemistry of Biological Macromolecules

Prereq: CAS CH 352, GRS CH 651, CH 652, CH 621, or consent of instructor. Physical properties and structures of proteins and related biological macromolecules. Size and shape of macromolecules; denaturation and cohesive forces in proteins; protein folding methods for studying biological macromolecules in solution and in the crystalline state. Three hours lecture. Mohr. 4 cr, 2nd sem.

GRS CH 724 – Special Topics in Biochemistry: DNA Nanotechnology (Fall 2010)

Prereq: GRS CH 621. Structural biology of DNA. Synthetic DNA objects, DNA templated synthesis, DNAzymes. While biological function will be mentioned, the main focus is DNA in nanotechnology, not the involvement of DNA in cell and molecular biology. Three hours lecture. Tullius. 4 cr, 1st sem. T/TH 9:30am – 11am.

GRS CH 731 – Special Topics in Inorganic Chemistry

Prereq: GRS CH 631. Selected topics of current research interest in inorganic and bioinorganic chemistry. Caradonna, Elliott. 4 cr, 1st sem.

GRS CH 741 – Organic Spectroscopy and Structure Determination

Prereq: GRS CH 641, CH 651, or equivalent. Spectroscopic methods in organic structure determination, with main emphasis on nuclear magnetic resonance. Snyder. 4 cr, 2nd sem.

GRS CH 743 – Organometallic Chemistry

Prereq: GRS CH 631; recommended: CH 641, CH 642, and CH 643, or consent of instructor. Structure and bonding in transition metal organometallic compounds; descriptive chemistry of organometallic compounds; fundamental organometallic reaction mechanisms; important industrial catalytic processes; organometallic compounds in organic synthesis. 4 cr, either sem. Not offered 2010/2011.

GRS CH 744 – Chemical Biology

Prereq: GRS CH 621. Introduction to research at the interface of chemistry and biology. This course will explore how an understanding of the structure and reactivity of proteins and small molecules can be blended with the techniques of molecular biology to probe and manipulate biological systems in new and interesting ways. Reading, presenting, and evaluating current literature will be a significant component of the course. Three hours lecture. Perlstein. 4 cr, 1st sem. M/W 12:30pm – 2pm.

GRS CH 751 – Advanced Topics in Physical Chemistry

Prereq: GRS CH 652. Current topics of research in theoretical, computational, and experimental physical chemistry. The course content varies with instructor. 4 cr, either sem. Not offered 2010/2011.

GRS CH 752 – Advanced Topics in Chemical Physics

Prereq: GRS CH 652. Current topics of research in theoretical, computational, and experimental chemical physics. Content varies with the instructor but may include material from such areas as advanced methods in molecular spectroscopy and magnetic resonance, nonlinear laser-induced phenomena, and photoionization and electron-molecule scattering. 4 cr, either sem. Not offered 2010/2011.

GRS CH 801 – Graduate Research Methods and Scholarly Writing

Introduces beginning graduate students to the fundamental methods of research and scholarship necessary for a successful career as a graduate student, teacher and independent research scientist.

Directed Study or Research Courses

GRS CH 901, 902 PhD Research in Chemistry

Instructor and hours arranged. Variable cr, 1st & 2nd sem.

GRS CH 903, 904 MA Research in Chemistry

A written report at the end of each semester is required. Instructor and hours arranged. Variable cr, 1st & 2nd sem.