Tagged: Plectosphaeroic Acid A

NIH Funds Alkaloid Synthesis Research

February 1st, 2011 in Faculty, Front Page, Grants, NIH, Stephenson, Corey

Prof Corey Stephenson

Professor Corey Stephenson

Professor Corey Stephenson and his group have received a 5-year, $1.7 million  award from the National Institutes of Health (NIGMS) to develop novel catalytic approaches to the synthesis of alkaloid natural products. These visible light-mediated methods provide innovative avenues toward challenging molecular architectures with broad biological activity.

The Stephenson Group focuses on performing syntheses in an environmentally conscious way. By using visible light, they prepare waste-free, non-toxic “reagent” complex natural products.  Since most organic molecules do not  absorb visible light, they can use photosensitive catalysts (widely studied for their photophysical properties) to carry out transformations under mild conditions in the presence of otherwise reactive functional groups. These new chemical reactions will enable the synthesis of biologically active natural products implicated in cancer, infection, and cardiovascular disease.

Professor Corey Stephenson. Alkaloid Synthesis Using Visible Light

Alkaloid Synthesis Using Visible Light

Professor Stephenson. Alkaloid Synthesis Compound

Plectosphaeroic Acid A

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