Tagged: Bjoern Reinhard
The NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBETS) has funded Bjoern Reinhard and his Co-Investigator, Professor Luca Dal Negro (Electrical & Computer Engineering,) to combine the advantageous photonic and plasmonic properties of nanostructured surfaces to develop a multiparametric responder that improves sensitivity and selectivity of conventional biosensing platforms through combined analysis of elastic and inelastic light-scattering processes. The award, “Multiparametric Optical Sensing of Microbes on Plasmonic Nanostructures,” is for $300K over three years.
Recently reported in PNAS, Bjoern Reinhard and his collaborator at the BU Medical School, Dr. Suryaram Gummuluru, have confirmed a unique HIV-1 DC attachment mechanism using lipoparticles with defined surface composition. The mechanism is dependent on a host-cell–derived ligand, GM3, and is a unique example of pathogen mimicry of host-cell recognition pathways that drive virus capture and dissemination in vivo. These insights provide the basis for the development of artificial virus nanoparticles with host-derived surface groups that inhibit the HIV-1 trans-dissemination pathway through dendritic cells. The virus parasite uses these dendritic cells to facilitate its dissemination, while avoiding recognition.
The article by Bjoern Reinhard, “Molding the flow of light on the nanoscale: from vortex nanogears to phase-operated plasmonic machinery” (Nanoscale, 2012, 4, 76-90; DOI: 10.1039/C1NR11406A), was amongst the top ten accessed articles from the online version of Nanoscale in February 2012. Launched in 2009, Nanoscale is a new peer reviewed journal publishing experimental and theoretical work across the breadth of nanoscience and nanotechnology.
The Reinhard Group research focuses on new optical materials and their application to interrogate fundamental life processes. They explore the interface between nanotechnology and biological systems. For an overview of current research projects, please visit their group’s website.
Research Media.EU disseminates information about advances in innovation to the wider scientific, technology, and research communities. Among its focus areas is Nanotechnology and US Research.
Recently, they interviewed Professor Bjoern Reinhard about his work on Epidermal Growth Factor Receptors (EGFRs), which are important cancer biomarkers, and which Research Media has identified as an important innovation in nanotechnology.
In addition to obtaining Professor Reinhard’s insights, the article described in detail the impact of this work and profiled the Reinhard Laboratory. To download a PDF of the interview/profile, click here.