Sean J. Elliott

Associate Professor, Department of Chemistry

Associate Professor, Molecular, Cellular Biology and Biochemistry Program

Bioinorganic Chemistry and Metallobiochemistry

• Voltammetric studies of Metalloproteins
• Enzymes involved in nitrogen, sulfur, and selenium metabolism
• Development of proteomic tools for the better understanding of metalliobiochemistry

Office: LSEB 707
Phone: 617-358-2816
Fax: 617-353-6466
E-mail: elliott@bu.edu

Office hours: By appointment

• B.A. in Chemistry (summa cum laude) and English, Amherst College, 1994
• Ph.D. in Bioinorganic Chemistry, Caltech, 2000

• Gitner Award for Distinguished Teaching, Boston University, 2007
• National Science Foundation CAREER Award, 2005
• EMBO Postdoctoral Long-term Postdoctoral Fellow at the University of Oxford, 2000-2001

• National Science Foundation
• National Institutes of Health
• The Medical Foundation

• Boston University Program in Bioinformatics

• CH 633 - Physical Methods in Inorganic and Bioinorganic Chemistry
• CH 634 - Special Topics in Inorganic Chemistry: Metallobiochemistry
• CH 109/110 - General and Quantitative Analytical Chemistry

My laboratory investigates the interplay between biological systems and redox-active species (e.g., metal ions, organic radicals, disulfide bonds, reactive oxygen species). Our emphasis is on the kinetic and thermodynamic basis for catalytic redox chemistry, as well as the molecular impact of metal ions and reactive oxygen species upon cells. Two core methodologies are being implemented and applied to a range of of biological problems: (1) protein film voltammetry (PFV), a direct electrochemical method, is used to study previously inaccessible catalytic systems; and (2) proteomic techniques are used to assess the impact of redox-active species (such as transition metals and reactive oxygen species) within living systems to investigate metal-ion import, packaging, and co-factor synthesis.

Elliott Group Homepage