TitleRates and cost of hospitalisation before and after initiation of antiretroviral therapy in urban and rural settings in South Africa
AuthorsBrennan AT, Meyer-Rath G, Fox MP, Modisenyane T, Tshabangu N, Mohapi L, Rosen S, Martinson N
PublicationJ Acquir Immune Defic Syndr. 2013 Mar; 62(3):322-328.
AbstractAbstract Few studies have compared hospitalisations before and after antiretroviral therapy (ART) initiation in the same patients. We analysed the cost of hospitalisations among 3,906 adult patients in two South African hospitals, 30% of whom initiated ART. Hospitalisations were 50% and 40% more frequent and 1.5 and 2.6 times more costly at a CD4 cell count <100 cells/mm3 when compared to 200–350 cells/mm3 in the pre-ART and ART period, respectively. Mean inpatient cost per patient year was USD 117 (95% confidence interval, CI, 85–158) for patients on ART and USD 72 (95% CI, 56–89) for pre-ART patients. Raising ART eligibility thresholds could avoid the high cost of hospitalisation before and immediately after ART initiation