TitlePoorer ART Outcomes with Increasing Age at a Large Public Sector HIV Clinic in Johannesburg, South Africa
AuthorsMhairi Maskew, MBBCh Alana T. Brennan, MPH A. Patrick MacPhail, PhD, FCP, FRCP Ian M. Sanne, MBBCh, FCP and Matthew P. Fox, MPH, DrPH
PublicationJournal of the International Association of Physicians in AIDS Care. 2012 Feb; 11(57):57-65.


As the current HIV-positive population ages, the absolute number of patients >50 years on treatment is increasing.


We analyze the differences in treatment outcomes by age category (18-29, 30-39, 40-49, 50-59, and 60) among 9139 HIV-positive adults initiating ART in South Africa.


Although older patients are at higher risk of mortality and have poorer immunological responses than their younger counterparts, they are more likely to adhere to care and treatment in the first 24 months on ART.