The President’s Malaria Initiative (PMI) is an interagency initiative led by USAID and implemented together with CDC. It is overseen by a U.S. Global Malaria Coordinator and an Interagency Steering Group made up of representatives from USAID, CDC/HHS, the Department of State, the Department of Defense, the National Security Council, and the Office of Management and Budget. The goal of PMI is to reduce malaria-related deaths by 50% in 15 countries that have a high burden of malaria through proven curative and preventive interventions, including insecticidetreated nets (ITNs), indoor residual spraying (IRS), intermittent preventive treatment for pregnant women (IPTp), and artemisinin-based combination therapies (ACTs). In late May 2011, PMI commissioned an external evaluation team to review the first five years (FY06-FY10) of PMI’s activities. Over the course of seven months, the evaluation team reviewed extensive documentation; interviewed key personnel in Washington, Atlanta, and Geneva; conducted five country site visits (Angola, Malawi, Rwanda, Senegal, and Zambia); and conducted e-mail and telephone interviews with malaria program personnel from the other 10 PMI focus countries.