Michael W. Otto, Ph.D. - Director, Translational Research
Professor of Psychology
Dr. Otto is Professor of Psychology at Boston University and Director of the Translational Research Program at the Center for Anxiety and Related Disorders. Dr. Otto specializes in the cognitive-behavioral treatment (CBT) of anxiety, mood, and substance use disorders. An enduring theme across these disorders is the role of exposure-based emotional tolerance/acceptance strategies in improving mental health. Dr. Otto has current and past federal funding from NIMH and NIDA, and his research focuses on difficult-to-treat populations, including the application of cognitive-behavioral strategies to patients who have failed to respond to previous interventions, as well as developing novel strategies for bipolar disorder and substance use disorders. Current research includes investigations of potential moderators of CBT efficacy, including several translational-research agendas ranging from studies of de novo fear conditioning to the application of putative memory enhancers (e.g., d-cycloserine) to facilitate exposure-based treatments. Dr. Otto also focuses on health behaviors ranging from medication adherence to engagement in exercise. Dr. Otto has published over 270 articles, chapters, and books spanning his research interests, and was recently identified as a “top producer” in the clinical empirical literature. For clinical training, he has numerous treatment manuals published in the Treatments That Work series for Oxford University Press. Dr. Otto is past President of the Association for Behavioral and Cognitive Therapies (formerly AABT), a fellow of the American Psychological Association, and a member of the Scientific Advisory Board for the Anxiety Disorders Association of America. Dr. Otto is a regular provider of continuing education and continuing medical education workshops across the United States.
Selected Journal Publications
Calkins, A. W., Otto, M. W., Cohen, L. S., Soares, C. N., Vitonis, A. F., Hearon, B. A., & Harlow, B. L. (in press). Psychosocial predictors of the onset of anxiety disorders in women: Results from a prospective 3-year longitudinal study. Journal of Anxiety Disorders.
Dhonnchadha, B. Á. N. , Szalay, J. J., Achat-Mendes, C., Platt, D. M., Otto, M.W. Spealman R. D., & Kantak K. M. (in press). D-cycloserine delays reacquisition of cocaine self-administration by augmenting extinction learning. Neuropsychopharmacology.
Otto, M. W., McHugh, R. K., & Kantak, K. M. (in press). Combined pharmacotherapy and cognitive-behavioral therapy for anxiety disorders: Medication effects, glucocorticoids, and attenuated outcomes. Clinical Psychology: Science and Practice.
Otto, M. W., Tolin, D. F., Simon, N. M., Pearlson, G. D., Basden, S., Meunier, S. A., Hofmann, S. G., Eisenmenger, K., Krystal, J. H., & Pollack, M. H. (in press). The efficacy of D-cycloserine for enhancing response to cognitive-behavior therapy for panic disorder. Biological Psychiatry.
Powers, M. B., Smits, J. A., Otto, M. W., Sanders, C., & Emmelkamp, P. M. (2009). Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: A randomized placebo controlled trial of yohimbine augmentation. Journal of Anxiety Disorders, 23, 350-356.
Safren, S. A., O’Cleirigh, C., Tan, J. Y., Raminani, S. R., Reilly, L. C., Otto, M. W., Mayer, K. H. (2009). A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychology, 28, 1-10.
Selected Recent Books
Otto, M. W. & Pollack, M. H. (2009). Stopping anxiety medication (Therapist guide,. 2nd Edition). New York: Oxford University Press.
Otto, M. W., Reilly-Harrington, N. A., Kogan, J. N., Henin, A., Knauz, R. O., & Sachs, G. S. (2009). Managing bipolar disorder: A cognitive-behavioral approach. (Workbook). New York: Oxford University Press.
Otto, M. W. & Smits, J. A. J. (2009). Exercise for mood and anxiety disorders (Workbook). New York: Oxford University Press.
Otto, M. W. & Hofmann, S. G. (Eds). (in press). Avoiding Treatment Failures in the Anxiety Disorders. New York: Springer.