Generalized Anxiety Treatment Evaluation (GATE)

We are currently conducting a free research study comparing the effectiveness of yoga, cognitive-behavioral therapy (a form of talk therapy), and stress education in the treatment of generalized anxiety disorder (GAD).
This study involves having a formal psychiatric interview, filling out questionnaires, ECGs, saliva samples, a urine test for drugs of abuse, and study visits over 12 weeks. Each study visit will take a few hours. 
Qualified participants will be compensated for time and travel. 

Generalized Anxiety: A Treatment Evaluation (GATE) Study
 
Do you worry a lot?

​Are you anxious?

Do you feel nervous most of the time?

​Do you have physical symptoms like muscle tension, difficulty sleeping, or poor concentration?

​If you answered YES to these questions and are over 18 years old, you may be eligible to receive treatment for Generalized Anxiety Disorder at no cost as part of a research study funded by the National Institute of Health at Boston University.

​Contact us:

Call: (617) 358-2249
Email: gatestudy@bu.edu

 
What is Generalized Anxiety Disorder (GAD)?

Generalized anxiety disorder (GAD) is characterized by difficulty controlling worry and distressing levels of anxiety about a number of different areas in a person’s life.  People with GAD might worry excessively about accomplishing day-to-day tasks, their performance in school or work, the health and safety of family members or their selves, or many other arenas of their lives. The core feature of GAD is that the level of worry and anxiety is greater than the situation warrants, and that the worry and anxiety is very difficult to control.  The severity and difficulty controlling this worry tends to cause great interference in a person’s daily life, their relationships, and their ability to functioning.    

Individuals suffering from GAD often worry about a number of areas of their life, such as their relationships or schoolwork even when those things are going quite well because they are also concerned about something going wrong in the future.  As a result, they may have difficulty concentrating because their minds are continually jumping to something they are worried about. Oftentimes, these symptoms of anxiety and worry will be accompanied by periods of irritability, tension, restlessness, difficulty sleeping, feeling easily fatigued and other physical symptoms. 

​About 3% of the adult population in the United States suffers from GAD, and many of those people also suffer from depression or other anxiety disorders.  Symptoms of generalized anxiety may wax and wane throughout a person’s life, but rarely disappear completely without proper treatment.
 

About the Study

We are currently conducting a research study that provides treatment for generalized anxiety disorder (GAD) to eligible participants at no cost.  The goal of the study is compare the effectiveness of three psychological treatments for GAD:

​ – Cognitive-Behavioral Therapy (CBT)

– Yoga Therapy

– Stress Education Therapy



What Does the Study Involve?

This study involves: ·A formal psychiatric interview ·Weekly group treatment sessions for 12 weeks ·Periodic interview and questionnaire assessments to track progress ·Several electrocardiograms and saliva samples

​Each study visit will take a few hours, and will take place in our clinic at Boston University. Participants will receive financial compensation for these visits. Treatment will be free of charge and be delivered by qualified instructors.  

Who is the Study For?

This is a study for adults in the Boston area who are suffering from Generalized Anxiety Disorder (GAD), which is a condition characterized by severe and uncontrollable worry and anxiety about a number of different areas of a person’s life.  Click here to read more about GAD.  

If you have had extensive experience with CBT or yoga in the past 3 years you may not be eligible.  If you are unsure if this applies to you, please call and ask.

Who We Are

This study is being conducted at the Psychotherapy and Emotion Research Laboratory of the Center for Anxiety and Related Disorders at Boston University.  The research is led by Stefan Hofmann, Ph.D.    

​This study is funded by the National Center for Complementary and Alternative Medicine (NCCAM), a branch of the National Institute of Health (NIH).   
 

What will the treatments look like? 

Each of the three treatments is conducted by qualified trainers in groups of 4-6 people with two instructors per group.  Eligible participants will be assigned randomly to either one of these therapies. All treatments consist of 12 weekly sessions (two hours each), as well as assigned activities in between sessions that offer the opportunity to solidify the knowledge learned in session on your own time.  The groups will meet at the Center for Anxiety and Related Disorders at a time that is convenient for everybody.
 
Frequently Asked Questions

When are the treatment sessions and how much time will they take? The assignment to the therapies will be random. The time of the groups will be determined based on the availability of the participants in the group and the instructors.  You will be expected to attend treatment sessions each week for 12 weeks, and the sessions are 2 hours long.  There will also be periodic evaluations of progress and other study procedures which could require additional visits.    
Where do the study visits occur? All study visits occur at Boston University’s Center for Anxiety and Related Disorder at 648 Beacon St, Boston, MA.  We are located right next to the Kenmore T stop for easy access by public transportation. 
Will I be compensated for my participation? Eligible participants may receive up to $140 for participating in a variety of study visits. The therapies will be free of charge.  This study is not suited for people who are primarily interested in compensation.  This study is for people who have difficulties with worry and anxiety and are interested in getting treatment for those problems.    
Is this individual or group treatment? All treatment is done in a group format.  Each group will consist of 4-6 adult participants who are going through similar difficulties with generalized anxiety and managing worry.  You will receive periodic evaluations throughout the study that will be conducted individually with one of the study clinicians.  
Will I be able to choose which treatment I receive? No, you will be randomly assigned to one of the three treatments.  Each of the three treatments have been shown in previous research to help some people, however, and you will receive regular evaluations of your progress regardless of your treatment condition.  
How do I know if I am eligible for the study? The best way to find out whether this study is a good fit for you is to call us at 617-358-2249.  We will ask you some preliminary questions about your symptoms of anxiety and worry, and may schedule a more in-depth assessment at our clinic if it seems like the study may be a good fit.  However, if you already have extensive experience with either of these treatments in the last three years you may not be eligible. If you are unsure about what this means for you, please call us.  

The GATE Study

Phone: (617) 358-2249

Email: gate@bu.edu

 

http://www.gatestudy.org/home.html