Research on Intensive Treatment for Panic Disorder in Adolescents

Researchers at the Center for Anxiety and Related Disorders at Boston University are conducting a study to evaluate the effect of 3 single doses of medication (d-cycloserine) on the effectiveness of an 8-day intensive cognitive-behavioral therapy for panic disorder in adolescents. This therapy relies on exposure (regular and stepwise practice with sensations or events that a person finds frightening) to help treat people with panic disorder.

Study participants will receive research treatment. The participants will be randomly assigned to receive either (a) 3 doses of d-cycloserine in conjunction with therapy of (b) 3 doses of placebo (sugar pill) in conjunction with therapy. The treatment will teach evidence-based strategies to adolescents and parents to overcome the symptoms of panic.

All research treatment and assessments are offered at no cost to eligible families.

Who may be eligible?

Adolescents (12-17 years of age) who meet criteria for panic disorder with or without agoraphobia (characterized by recurring panic attacks, concerns about having more panic attacks, and/or considerable behavioral changes) may be eligible for the treatment study.

Who do I contact for more information?

For more information, please call (617) 353-9610 and ask to speak with Dr. Ovsanna Leyfer. You can also email our registered nurse, Bonnie Brown at A member of our clinical staff will be happy to speak with you about our program and answer any questions you may have.