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- Hurricane Sandy Relief: Cash & Clothing Drive8:00 am
- Thai Iced Tea Sale10:00 am
- Stephen A. Frank: Exploring My Kodachrome Dreams-Photographs from the West, Southwest, & Maine 2010-201211:00 am
- Challah for Hunger11:00 am
- Don't Just Do Something -- Sit There!12:00 pm
- Marsh Chapel: Common Ground Communion12:20 pm
- "Jouissance vous donneray: French poetry and music (1200-1650)"12:30 pm
- BU's Road to Washington: An Election Year Series 12:30 pm
- BUCH Fellows' Seminar: Pat Hills12:30 pm
- BU Law Review Book Symposium - On Constitutional Obligation and Disobedience12:50 pm
- Note Taking2:00 pm
- Sesame Street: Revolution in Educational Television (COM Research Colloquium Series) 3:30 pm
- Second Sex/Third Body: Beauvoir, Cixous4:00 pm
- SAR Information Session4:00 pm
- Obama's Foreign Policy: A European View - A talk by Zaki Laïdi4:00 pm
- Bud Mishra - Courant Institute of Mathematical Sciences, NYU4:00 pm
- Anthropology Dissertation Defense of Arianna Huhn4:00 pm
- Resume Writing Express4:00 pm
- Inga Muscio and "The Invisible War"4:30 pm
- Cover Letter Writing Express4:30 pm
- Decision Making5:00 pm
- 2nd Annual Peter Berger Lecture in the Comparative Study of Religion5:00 pm
- Atom Group5:00 pm
- SAMBA5:30 pm
- Opening Reception: Stephen A. Frank5:30 pm
- SojournBU Bay State Cadre6:00 pm
- Bicentennial Petra: Celebration and Trepidation at a Wonder of the World6:00 pm
- Cinematheque: An Evening with Benoit Jacquot6:00 pm
- Friends Speaker Series - Nelson DeMille6:00 pm
- International Christian Fellowship6:00 pm
- Tora Dojo6:30 pm
- The Effect of Gamma Rays on Man-in-the-Moon Marigolds7:30 pm
- The Sussman Variations7:30 pm
- All Shook Up8:00 pm
- The Dear Abbeys and Tufts Beelzebubs: Men Being Manly8:00 pm
Bud Mishra - Courant Institute of Mathematical Sciences, NYU
Title: Towards Cancer Hybrid Automata. Abstract: Recently, we introduced Cancer Hallmark Automata, a formalism to model the progression of cancers through discrete phenotypes (so-called “hallmarks”). The classification of various cancers using stages and hallmarks has become common in the biology literature, but primarily as an organizing principle, and not as an executable formalism. The precise computational model developed here aims to exploit this untapped potential, namely, through automatic verification of progression models (e.g., consistency, causal connections, etc.), classification of unreachable or unstable states (e.g., “anti-hallmarks”) and computer-generated (individualized or universal) therapy plans. This talk builds on a phenomenological approach, and as such does not need to model the biochemistry underlying the progression. Rather, it abstractly models transition timings between hallmarks as well as the effects of drugs and clinical tests, and thus allows formalization of temporal statements about the progression as well as notions of timed therapies. The model proposed here is ultimately based on hybrid automata (with multiple clocks), for which relevant verification and planning algorithms exist in the literature. "Towards Cancer Hybrid Automata," (with L. Olde Loohuis and A. Witzel), First International Workshop on Hybrid Systems and Biology: HSB 2012, Newcastle upon Tyne, UK, September 3, 2012.
When | 4:00 pm to 5:00 pm on Thursday, November 8, 2012 |
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Location | MCS 148 |