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Special Studies


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Diet Validation Study (1998 - 2000). In the late 1990's, 400 BWHS participants took part in a diet validation study. They reported what they had eaten several times over the course of a year, and they also kept food diaries for a week. Dr. Shiriki Kumanyika, a member of the BWHS Advisory Board and the BWHS expert on diet, conducted the study to find out how well the diet questions on the 1995 BWHS health questionnaire reflect what participants really ate. The results of this study showed that dietary information provided by BWHS participants is reliable enough to be highly useful in studies of diet and disease (see Publication List, articles #6, 22 and 34 for full reference). The study is a step toward the goal of finding out if certain foods cause or prevent particular illnesses.
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Physical Activity Validation Study (2001 - 2002). A total of 115 BWHS participants participated in a physical activity validation study. Dr. Lucile Adams-Campbell invited participants who were within traveling distance of Howard University to come in for various measurements (for example, blood pressure, height, weight) and to wear a device called an accelerometer for a week. The accelerometer, which looks like a wristwatch and is worn on a belt, measures how much movement occurs. We compared how well the BWHS survey questions on physical activity correlated with the accelerometer measures. We found the survey information to be sufficiently accurate for assessing how physical activity influences various illnesses.
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Cheek Cell Study (2004 - 2009). Cells obtained by swishing the mouth with mouthwash contain genetic material. Recent scientific findings suggest that certain genes may play a role in how the body handles carcinogens. For example, people with one form of a particular gene might clear the body of carcinogens from cigarettes much faster than people with other forms of the gene. The BWHS will assess genes of this type. The ultimate goal is to be able to identify what makes some women more susceptible to particular illnesses. Between 2003 and 2007, we invited BWHS participants to provide cheek cell samples by means of mouthwash. Results from the genetic tests that will be performed in this study are generally not suitable for use as clinical tests for medical care. Instead, they provide important population information when combined with tests from many other women. Therefore, individual results will not be provided to participants.
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Physical environment study (2005-2010). Exercise decreases the occurrence of many illnesses, such as diabetes and heart disease, and helps with weight control. It is possible that failure to exercise is a response to surroundings that make it difficult to be active. BWHS investigators are focusing on three cities, Los Angeles, New York, and Chicago, for which they will be able to obtain detailed information on the physical surroundings of the BWHS participants who live in those cities. Experts in family planning will provide data on sidewalks, traffic, parks, and other features of the environment. BWHS investigators will then study how these factors are related to BWHS participants’ levels of exercise and weight change. The results from the study should provide compelling evidence for the need for better city and transportation planning. |
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Blood Collection Feasibility Study (2006). Very little is known about how substances found in blood, such as markers of inflammation, affect disease risk in black women. The BWHS hopes to study these factors. As a first step the BWHS invited some participants to provide blood samples by going to nearby blood collection centers run by Quest Diagnostics, a nationwide company used by many doctors for routine lab work. Participants were reimbursed for their time and effort. This study demonstrated that it is feasible to collect blood samples from BWHS particpants. BWHS investigators are trying to obtain support from The National Institutes of Health to collect blood samples from all particpants who are willing to give one.
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