Three Steps to a Better World: A Living Patch

One percent of newborns are born with congenital heart defects, whose repair usually requires [...]multiple surgeries. That’s because the synthetic materials used in the repair of the defects fail as a result of calcification, infection, or thrombosis, and are not capable of growing with the child. Andrew Schiff (ENG’12), a Lutchen Fellow, would like to make a better patch, one made of Mesenchymal Stem Cells MSCs (MSCs) and Human Umbilical Vein Endothelial Cells (HUVECs) taken from the child. A living patch made from the child’s cells would minimize the risk of infection and would grow with the child’s body. This lab has been able to succesfully pattern our MSCs in an aligned fashion, using the Microcontact Printing Technique. -undergraduate-summer-research/

Tags: engineering, biomedical, heart disease, stem cells

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