Project BoBo

Project BoBo (Boston-Bologna) was born in June 2003, from a newly established collaboration between the Brain and Vision Research Laboratory (Boston University-BME, Neuroscience, and Neurology), University of Bologna (Facolta di Scienze Motorie and Istituto di Fisiologia Umana e Generale), and Ospedale S. Orsola-Malpighi. Continuation of Project BoBo is made possible by a research grant from the Fondazione Carisbo, Bologna.

What is BoBo? Using psychophysics and analytical tools of behavioral and neuroimaging data analysis. We study visual motion perception in stroke patients. Our interests are to determine: (1) how visual motion deficits impact our motor performance, in particular navigation; (2) how visual motion deficits cluster; and (3) how visual motion performance relates to the site and the side of the patient's lesion.

One of the exciting outcomes of BoBo is a symposium to be held December 12-15, 2003 in Bologna, and two tutorials: one on fMRI methods and the other on computational neurophysiology. Please look soon for more exciting outcomes, such as scientific papers coauthored by the members of BoBo research group.

Prof. Lucia M. Vaina, M.D., Ph.D. Project BoBo Co-director
Lucia "commuted" between Bologna and Boston (Boston being her main base). Creator of Project BoBo, she enjoys clinical neuroscience work as much in Bologna as in Boston. Between 2003-2005 she has fostered rewarding collaborations with Bologna's Department of Human and General Physiology, Medical School, Faculty of Motor Sciences, and Ospedale S. Orsola-Malpighi. All this was possible thanks to an award from the Ministero dell'Università e della Ricerca Scientifica e Tecnologica Italiano (MURST) under the program Rientro dei Cervelli, that she held between 2003-2005. Now these collaborations successfully continue thanks to a grant from the Fondazione Carisbo-Bologna, between 2005-2007. Through "skype" Lucia directs the development of new experiments at Bologna, and in Boston she tests them and together with the Brain and Vision Research Laboratory she studies selective deficits on these tests in stroke patients.
Prof. Salvatore Squatrito, M.D. Project BoBo Co-director
Who made it all possible! Salvatore has done elegant physiological studies on the parietal visual system of our "cousin" the macaque monkey, but now he has moved to the motor system and motor sciences. He is the President of la Facoltà di Scienze Motorie. The plan is to sue the tests developed under BoBo to study learning of normal subjects, and compare performance of normal subjects with that of sports trained subjects on tests such as detection of time-to-collision and visual-motor tasks.
Gabriella Pandiani, M.D.
The pilar of neuropsychological assessment of stroke patients in the Padiglione Albertoni-Reparto Alleanti of rehabilitation. Gabriella's enthusiasm for the project is contagious, and her expertise much needed.
Maria Grazia Maioli
Who makes sure all details that matter are taken care of and that BoBo rolls happily forward. Without her it would be hard to keep the dynamism of the group.
  Prof. Renato Campanini, Ph.D.
Professor of Physics at the University of Bologna and working on imaging. He is the one who keeps a formal eye on Danilo's progress and makes sure he does not fall asleep in the magnet or modeling cortical connectivity (known to happen).
Danilo Dongiovanni, Ph.D.
Postdoctoral Research Associate, Brain and Vision Research Laboratory, Boston University and Department of Physics, University of Bologna, Italy. Modelling functional brain connectivity using fMRI data.
Leonardo Sassi, M.S.
Senior Programmer who develops virtual reality experiments in spatial navigation and spatial cognition.

Scott Beardsley, Ph.D.
Finn Calabro
Elif Sikoglu
Sergei Soloviev, M.S.
Robert Pitts, Ph.D.

Members of the Brain and Vision Research Laboratory in the Department of Biomedical Engineering and Program in Neuroscience at Boston University. Without them Project BoBo would just have been an optical and cognitive illusion.

Anna Minguzzi, Ph.D.
Oscillating between motion-emotions, motion-learning and music.
Andrea Ballabeni, Ph.D.
A rare bird! Neural modeler at heart and physiologist by trade. He'll soon hit the real world of employment.


FUNCTIONAL PLASTICITY AND CORTICAL REORGANIZATION IN THE HUMAN VISUAL AND MOTOR SYSTEMS

Bologna--December 12-15, 2003

Organizers: Lucia M. Vaina
Salvatore Squatrito
Carlo Franzini
Location: Aula della Scuola Superiore di Studi Umanistici
Via Marsala, 26
Bologna
Registration: 25 euro for each symposium (main symposium & mini-symposium).
50 euro for each dinner.
Payment should be made at the beginning of the main symposium.
Hotel: INFORMATION SOON

Scientific and Social Program

SYMPOSIUM

DECEMBER 12

2:00pm Opening
3:00pm-4:30pm Jon Kaas (USA)
Plasticity of sensory and motor systems after injury in mature and developing primates.
4:30-5:00pm Tea and coffee break
5:00-6:30pm Charles Gilbert (USA)
Neural mechanisms of perceptual learning.
7:00pm Cocktails & Dinner

DECEMBER 13
VISION

9:00-10:00am Barbara Dosher (USA)
Mechanisms and limits of perceptual learning.
10:00-11:00am Merav Ahissar (Israel)
Perceptual learning as a means for both modifying and exploring the relations between cortical processing and perception.
12:00pm Lunch
3:00-4:00pm Lucia M. Vaina (USA & Italy)
Mapping plasticity in the normal and damaged human visual system.
4:00-5:00pm Yves Rossetti (France)
The effect of visuo-motor plasticity on other brain functions: prism adaptation and unilateral neglect.
6:00-6:45pm Thomas F. Münte
The musician's brain as a model of neuroplasticity.
7:00-8:45pm Piano Concerto--Cristobal Curio (Germany)
(free and open to all participants and guests)

Location:  Aula Absidale di S. Lucia
Via de' Chiari 25/a
Bologna
Program:
* F. Mendelssohn Bartholdy
- A selection of "Songs without words"
* Bach / Busoni
- Choral Preludes
INTERMISSION
* F. Schubert
- A selection of Moments Musicaux / Impromptus
- Grande Sonata D960

9:00pm Dinner

DECEMBER 14
HISTORIC BOLOGNA/FREE DAY
(OPEN TO ALL PARTICIPANTS AND GUESTS)

10:00-1:00pm Palazzo Poggi--Guided tour (small fee)
RESERVATION NEEDED
http://urp.comune.bologna.it/IAT/IAT.nsf/0/4b785717cffe470fc1256bc300393937
or http://www2.unibo.it/avl/storia/storia.htm
Lunch-Individual
3:00pm Historic Bologna--Art and science in the Bologna churches
Enrico Morini and Sandro Turrini (University of Bologna)
(churches, architecture, history, art, the meridian of S. Petronio and so much more from two experts!!!!!!!)

We met in Piazza Maggiore near the main portal (1426-1438) of the Basilica of St. Petronio, in order to visit the Church and its Meridian Line. The Meridian Line, working in extension from the Summer Solstice to Winter Solstice, was traced on the floor of the left nave in 1655 by Giandomenico Cassini, the celebrated Italian astronomer. From the measure of the semidiameter of the solar image on the Meridian Line, Cassini, for the first time in the history of astronomy, succeeded in obtaining experimental confirmation of the eccentricity of the earth's orbit.

On Clavature street, a side street leading off from Portico del Pavaglione, we visited Santa Maria della Vita Church, designed in 1289 as a Hospital to care for the disabled, and subsequently (in 1600) transformed into a Church. We admired the Compianto sul Cristo morto, earthenware masterpiece of Nicolò dell'Arca.

We reached the splendid "Basilica di Santo Stefano" formed by seven Churches different in style and shape. This group of Churches is thought to be the most ancient Christian monument in Bologna, and St. Petronius himself, bishop (431-450) and protector of the town, is indicated as having designed the Basilica. The project was called "Santa Hierusalem", from the Latin, because of similarities to the Churches of the Holy Sepulchre in Jerusalem. In the so-called "Rotonda del Santo Sepolcro" we could see the reproduction of the Holy Sepulchre of Christ. Not far from Piazza Santo Stefano, we visited San Giovanni in Monte Church, another foundation of St. Petronius (5th century), built upon a hill reminding the mount of the Ascension of Christ. The Church underwent restorations in the 13th and the 15th centuries.

DECEMBER 15
THE MOTOR SYSTEM

9:00-10:00am Francesco Lacquantiti (Italy)
Visually guided interceptions. Learning to time or timing to learn?
10:00-11:00am Randolph Nudo (USA)
Role of neuroplasticity in motor recovery after stroke.
11:00-11:30am Tea and coffee break
11:30-12:30pm Julien Doyon (Canada)
Contributions of the cortico-striatal and cortico-cerebellar systems to motor learning examined through brain imaging and lesion studies.
12:30-1:30pm Paolo Maria Rossini (Italy)
Brain plasticity of the sensorimotor hand function: from experimental models to clinical applications.
Lunch-Individual
3:00-5:30pm Guided visit to the Department of Anatomy and Anatomy Museums and
Collections MUSEO delle CERE ANATOMICHE Luigi Cattaneo,
Via Irnerio, 48
http://www2.unibo.it/avl/storia/storia.htm
6:00-8:00pm INFORMAL DISCUSSION CONCLUDING THE SYMPOSIUM AND COCKTAILS

Some of the points discussed:

  • Successes thus far in these research areas.
  • What are the main problems in the sensory and motor systems that can be addressed effectively with the existing techniques?
  • Where is the field going?
  • Clinical applications.


Useful information for accompanying persons not directly interested in the symposium can be found at:
http://www.guidedarte.com/html/itinerari_tematici_english.html


Tutorials

DECEMBER 16
TUTORIAL and MINI-SYMPOSIUM: COMPUTATIONAL NEUROPHYSIOLOGY OF VISION

Organizers: Lucia M. Vaina (USA & Italy)
Salvatore Squatrito (Italy)
Claudio Galletti (Italy)

TUTORIAL: COMPUTATIONAL NEUROPHYSIOLOGY

9:00-1:00pm Scott Beardsley (USA)
Computational neurophysiology of vision--coding and decoding in the visual system.
Lunch-Individual

MINI-SYMPOSIUM: SAMPLING COMPUTATIONAL VISION

3:00-4:30pm Key Note Speaker:
Klaus-Peter Hoffmann (Germany)
Cortical and subcortical structures in vision.
4:30-5:00pm Coffee break
5:00-5:45pm Peter Földiák (UK) and Sergei Soloviev (USA)
Temporal coherence for the unsupervised learning of coordinate transformations.
5:45-6:30pm Martin Giese (Germany)
Learning representations of biological movements in brains and machines.
6:30-7:15pm Scott Beardsley (USA)
Symmetric complex motion perception in a biased neural representation.
7:30-8:00pm Computational storming


Project BoBo web page hosted by the Brain and Vision Research Laboratory (www.bu.edu/bravi).