Peer Reviewed Publications:


P Diep, S Pannem, J Sweer, J Lo, M Snyder, G Stueber, Y Zhao, S Tabassum, R Istfan, J Wu, S Erramilli, Darren Roblyer, “Three-dimensional printed optical phantoms with customized absorption and scattering properties.“ Biomedical Optics Express, 2015 Oct; 6(11)

Y Zhao, Darren Roblyer, “Spatial mapping of fluorophore quantum yield in diffusive media.” Journal of Biomedical Optics, 2015 Aug; 20(8) 086013.


J Jung, R Istfan, Darren Roblyer, “Note: A simple broad bandwidth undersampling frequency-domain digital diffuse optical spectroscopy system.” Review of Scientific Instruments, 2014 July; 85

R.P. Singh-Moon, Darren Roblyer, I.J. Bigio, S.Joshia, “Spatial mapping of drug delivery to brain tissue using hyperspectral spatial frequency domain imaging.” Journal of Biomedical Optics, 2014 Aug; 19(9)


Darren Roblyer, T O’Sullivan, R.V. Warren, BJ Tromberg, “Feasibility of direct digital sampling for disuse optical frequency domain spectroscopy in tissue.” Meas. Sci. Techn., 2013 March; 24(4) pdf

T O’Sullivan, A Leproux, J Chen, S Bahri, A Matlock, Darren Roblyer ,CE. McLaren, W Chen, A Cerussi, M Su, BJ Tromberg, “Optical imaging correlates with magnetic resonance imaging breast density and reveals composition changes during neoadjuvant chemotherapy.” Breast Cancer Research, 2013 Feb; 15


Darren Roblyer*, Ueda S*, Cerussi A, Durkin A, Leproux A, Santoro Y, Xu S, O’Sullivan T, Hsiang D, Mehta R, Butler J, Tromberg BJ. “Baseline tumor oxygen saturation correlates with a pathologic complete response in breast cancer patients undergoing neoadjuvant chemotherapy” Cancer Research. , 2012 July; *shared first authorship pdf

A. Cerussi ,R. Warren, B. Hill, Darren Roblyer, A. Leproux, A.F. Durkin, T.D. O’Sullivan, S. Keene, H.Haghany, T.Quang, W.M. Mantulin, and B.J. Tromberg, “Tissue phantoms in multicenter clinical trials for diffuse optical technologies”, Biomedical Optics Express, 2012 April; 3(5)


Darren Roblyer*, S. Ueda*, A. Cerussi, Tanamai W., A. Durkin, R. Metha, D. Hsiang, J. Butler, C.E. McLaren, W. Chen, B. Tromberg. “In Vivo Optical Imaging of Breast Cancer Oxyhemoglobin Flare Correlates with Neoadjuvant Chemotherapy Response One Day after Starting Treatment” Proceedings of the National Academy of Sciences, United States of America. 108 (35). (2011 Aug) *shared first authorship pdf

T. Muldoon, Darren Roblyer, M.D. Williams, V.M. Stepanek, R. Richards-Kortum, A.M. Gillenwater. “Nonivasive imaging of oral neoplasia with a high-resolution fiber-optics microendoscope” Head and Neck. (16). (2011 Mar) pdf


Darren Roblyer, C. Kurachi , V. Stepanek , R. Schwarz, M. Williams , A. El-Naggar , J. Jack Lee , A. Gillenwater, R. Richards-Kortum. “Comparison of Multispectral Widefield Optical Imaging Modalities to Maximize Image Contrast for Objective Discrimination of Oral Neoplasia” Journal of Biomedical Optics. 15 (6). (2010 Nov-Dec) pdf

T. Muldoon , N.Thekkek , Darren Roblyer, D. Maru , N. Harpaz , J. Potack , S. Anandasabapathy , R. Richards-Kortum, “Evaluation of Quantitative Image Analysis Criteria for the High-Resolution Micro-Endoscopic Detection of Neoplasia in Barrett’s Esophagus”, Journal of Biomedical Optics, 2010 Mar-Apr;15(2).

Mohammed Rahman, N. Ingole, Darren Roblyer, V. Stepanek, R. Richards-Kortum, A.Gillenwater, S. Shastri, and P. Chaturvedi, “Evaluation of A Low-Cost, Portable Imaging System for Early Detection of Oral Cancer“, Head and Neck Oncology, 2010 Feb;2(10).


Darren Roblyer , C. Kurachi , V. Stepanek , M. Williams , A. El-Naggar , J. Jack Lee , A. Gillenwater, R. Richards-Kortum. “Objective Detection and Delineation of Oral Neoplasia Using Autofluorescence Imaging” Journal of Cancer Prevention Research. 2 (5): 423-31. (2009 May) pdf


Darren Roblyer, Sokolov KV, El-Naggar A, Williams M , Kurachi C , Gillenwater A, Rebecca Richards-Kortum. “A Multispectral Optical Imaging Device for In Vivo Detection of Oral Neoplasia”Journal of Biomedical Optics. 13 (2). (2008 Mar-Apr) pdf

Javier, David*; Nitin, Nitin*; Darren Roblyer; Richards-Kortum, Rebecca, “Metal based nanorods as molecular specific contras agents for reflectance imaging in 3D tissues”, Nanophotonics. 2008 April;2


Darren Roblyer, Park SY, Richards-Kortum R, Adewole I, Follen M, “Objective Screening for Cervical Cancer in Developing Nations: Lessons from Nigeria”, Gynecologic Oncology. 2007 Oct;107(1 Suppl 1)

Nitin Nitin , David Javier , Darren Roblyer, Rebecca Richards-Kortum, “Widefield and High Resolution Reflectance Imaging of Gold and Silver Nanospheres”, Journal of Biomedical Optics. 2007 Sep-Oct;12(5)

Book Chapters:

Darren Roblyer, R. Schwarz, R. Richards-Kortum, “Fluorescence Spectroscopy”,  Handbook of Biomedical Optics, D. Boas, C. Pitris, N. Ramanujam (Editors), Taylor and Francis, 2011.

Darren Roblyer, A Cerussi, B.J.Tromberg, “Diffuse Optical Spectroscopic Imaging of Breast Cancer”,McGraw-Hill Series in Biophotonics,  James Tunnel (Editor), McGraw-Hill, 2011.

Conference Articles:

J. Jung, R. Istfan, Darren Roblyer, “Effect of modulation frequency bandwidth on measurement accuracy and precision for digital Diffuse Optical Spectroscopy (DOS).” Proc. of SPIE 8936, Design and Quality for Biomedical Technologies VII, March 2014

Darren Roblyer , C. Kurachi , A. Gillenwater, R. Richards-Kortum, “In Vivo Fluorescence Hyperspectral Imaging of Oral Neoplasia” , Proc. SPIE 7169, Advanced Biomedical and Clinical Diagnostic Systems VII, February 2009