Research Seminar “ Physical activity and the prevention of knee pain and functional limitation in knee OA.” - Dan White

12:00 pm on Wednesday, May 22, 2013
1:00 pm on Wednesday, May 22, 2013
Talbot 519
The focus of the seminar is to review the rationale and specific aims for Dan’s upcoming K-23 submission. The overall objective outlined in his proposal is to investigate whether regular levels of daily walking mitigates incident functional limitation in people with knee osteoarthritis. Dan plans to evaluate daily walking and functional limitation outcomes in the context of a large randomized clinical trial of adults at high risk of with symptomatic knee osteoarthritis. He will utilize data from accelerometer-measured steps over 7 days to characterize walking activity. Next he will utilize pain data collected before and after the accelerometer was worn to evaluate short-term increases in knee pain. Lastly, he will evaluate lean mass utilizing cross-sectional images of the upper leg from MRI and muscle strength from isokinetic and power measures from existing and prospectively collected data.