Lab Profiles

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Current Members

Irving J Bigio
IrvingIrving J. Bigio received his Ph.D. in Physics from the University of Michigan in 1974. From then until 2000 he was a scientific staff member at Los Alamos National Laboratory (New Mexico), including service as Leader of the Laser Science and Applications Program (1988-1994). He has been a Fulbright Senior Scholar at the Weizmann Institute of Science, in Israel, a Visiting Professor at the University of Copenhagen, Denmark and a Guest Fellow of Pembroke College at the University of Oxford, England. Dr. Bigio holds a number of patents for biomedical optics instrumentation, and has received three R&D-100 Awards for the development of biomedical optical devices. Since February 2001 he has been at Boston University, where he is Professor in the Departments of Biomedical Engineering, Electrical & Computer Engineering, and Physics. Dr. Bigio serves on several government advisory panels and on external advisory boards for companies and academic institutions. He is a Fellow of the Optical Society of America, the American Institute of Medical and Biological Engineering and the SPIE, and is a member of the American Physical Society. In addition to other research programs in biomedical optics, Dr. Bigio is currently leading a multi-institutional program under the NIH/NCI Network for Translational Research in Optical Imaging, comprising several medical research centers in the US and Europe. He is also the head of the Quantitative Biology and Physiology program, funded by the NIH, at Boston University.
Ousama A’Amar
Ousama Ousama M. A’Amar, obtained his BS in Electronics Engineering in 1989 and received his MS (1993) and Ph.D. (1997) in automatic control and digital signal processing from the National Polytechnic Institute of Lorraine (INPL), France. His MS and Ph.D. research focused on optical biomedical signals; namely autofluorescence and induced-fluorescence for cancer diagnosis and treatment. In 1996, he received the European Diploma in Medical Lasers from the University Nancy I, France and won the Young Researcher Prize of the French Society of Medical Lasers (SFLM). He worked as: Assistant Professor at the department of Biomedical Engineering, Al-Ahliyya Amman University, Jordan (1998/1999-2002/2003 – 2005/2006); Postdoctoral Research Associate at the Bioscience Division of Los Alamos National Laboratory, NM (1999-2001). Since 2001, he has been working as Senior Research Associate at the Biomedical Engineering Department in Boston University, MA. In the Biomedical Optics Lab, he leads research activities on optical spectroscopy and biomicroscopy for cancer diagnostics including prototyping of clinical devices and serving as liaison for research collaborations with clinical sites at Boston University Medical Center and other clinical research centers in the Boston area.
Bobby Liu
Bobby LiuWei-Han Bobby Liu received B.S. degrees from MIT in Chemistry and Chemical Engineering in 2007, and his M.S. in Chemical Engineering from Stanford University in 2009. He joined the Biomedical Optics Lab in 2010, and is currently pursuing his Ph.D. in Biomedical Engineering. His research involves apoptosis detection in mammalian cell cultures via elastic scattering spectroscopy, developing upon Christine Mulvey’s previous research in this lab.
Ali Badreddine
aliAli Badreddine graduated from Vanderbilt University in 2009 with a degree in Biomedical Engineering. He has created movies of averaged and live action potential propagation in crustacean nerves using a crossed polarization setup to monitor and track electric field-induced changes in birefringence (FICB) along the length of the nerve. He is currently working on detecting FICB in mammalian brain slices with an aim to develop this technology for studying neuronal diseases. His research is a progression of previous work done in this lab by Kurt Schoener, who developed a method of using spot illumination to detect AP-related activity in lobster walking leg nerves.
Joseph Angelo
joeangeloJoseph earned a B.S. degree in physics from Drexel University in 2010 with research experience in astrobiology at NASA’s Goddard Space Flight Center and a publication in theoretical chemistry under Dr Karl Sohlberg. After a year of service as an AmeriCorps member, he came to Boston University as an NSF GRFP Fellow and joined the Biomedical Optics Lab with Dr Irving Bigio at BU and the Biomedical Optics and Engineering Lab with Dr Sylvain Gioux at Beth Israel Deaconess Medical Center in 2012. His current work focuses on novel wide-field diffused imaging techniques aimed at image-guided surgery.


Recent Alumni

Durba Chaudhuri
durbachaudhuriDurba came to the USA with a M.Sc in Nanotechnology from University College London, U.K and a B.E in Electronics and Telecommunication from the University of Pune, India. She gained diversified research experience on solar cells, nano antenna materials, microbial load reduction in bio fertilizers, etc., working at the London Center for Nanotechnology, U.K;, the Indian Institute of Technology, India, and the Indian Council of Agriculture Research, India. She joined the Biomedical Optics lab in 2011, and obtained her MS on pharmacokinetic modeling of dyes across the blood brain barrier in 2013.
Carlos Segura
carlosseguraCarlos Segura, originally from Juarez, Mexico, received his BS in Mechatronics Engineering in 2009 from his hometown campus of the Monterrey Institute of Technology (ITESM). Before joining the Biomedical Optics lab in 2012, he acquired experience in manufacturing and R&D industries, focused mostly on instrumentation, tool and fixture design. He obtained his MS in 2014 on developing a brain-implantable probe with optical and electrical capabilities that can be used to characterize the tissue/electrode interface via optical spectroscopy.
Katherine Calabro
kcalabro Originally from Rochester NY, Katherine graduated from Penn State with a BS and a MS in Engineering Science in 2005 and 2006, respectively. When she started at BU in the Fall of 2006, she brought with her a background in Theoretical Electromagnetics and Modeling. In the Biomedical Optics lab, she worked on the development and improvement of mathematical tools such as the Monte Carlo Method to model photon transport in tissue. She completed this work and obtained her Ph.D. in 2012, and now works for Synopsys here in MA developing optical modeling tools.
Aysegul Ergin
Aysegul_Pic Aysegul Ergin, originally from Istanbul, Turkey, received her BS degree in Electronics Engineering from Istanbul University and her MS degree in Biomedical Engineering from Bogazici University in Istanbul , Turkey. She received her Ph.D. in Biomedical Engineering from the New Jersey Institute of Technology (NJIT) in 2008. Her PhD research was focused on the development of a laser glucometer, a compact and portable Raman spectroscopy system to detect and quantify glucose concentration in the aqueous humor of the eye to help diabetics. She joined the Biomedical Optics Lab in 2008 as a postdoctoral research associate to work on optical pharmacokinetics, drug extravasation and optical detection of blood-brain barrier disruption in vivo. She completed this work in 2012.
Christine Mulvey
Photo - MulveyChristine received an S.B. degree in Engineering Sciences from Harvard University in 2004. Her research with the Biomedical Optics Lab involved the application of elastic scattering spectroscopy to the detection of apoptosis, a type of cell death important in the treatment of cancer using chemotherapy. She obtained her Ph.D. in 2011, after which she accepted a post-doc position at Duke University.
Kurt J. Schoener
Kurt-MiamiKurt Schoener received a B.S. in Electrical Computer Engineering and a B.A. in International Affairs in 2002 from Lafayette College in Easton, PA.  He completed his Ph.D. in the spring of 2010 with the Biomedical Optics Lab.  His doctoral work focused on determining the physiological origins of the intrinsic action potential-modulated birefringence in axons.  He showed that the transient electric field of the propagating action potential is responsible for the observed behavior, which he named field-induced changes in birefringence, or FICB.