James Galagan, Ph.D.

photo of Dr. James Galagan

Associate Chair for Graduate Studies, Biomedical Engineering
Associate Professor, Biomedical Engineering and Microbiology
Associate Director, Systems Biology, National Emerging Infectious Diseases Laboratory
Associate Director, Microbial Genome Analysis, Broad Institute

Ph.D., Computational Neuroscience, MIT
B.S., Computer and Electrical Engineering, UC Davis

Phone: 617-358-0695
Email: jgalag@bu.edu
Office: LSEB #1002

Research Interests

Systems Biology, Infectious Diseases, Tuberculosis, Computational Biology, Genomics and Microbiology.

Current Research

Dr. Galagan’s research is focused on Systems Biology of microbial organisms, specficially Mycobacterium tuberculosis – the causative agent of tuberculosis – and the fungus Neurospora crassa.  The Galagan Lab is an interdisciplinary group that combines computational biology, genomics, and experimental lab work.  Specific interests and projects include:

  • Using a genomics, computational modeling, and experimental systems-identification techniques to reconstruct the gene regulatory network of M. tuberculosis.
  • Developing and experimentally validating computational models of microbial metabolism for M. tuberculosis and N. crassa.
  • Using high-throughput sequencing and comparative sequence analysis to study the functional evolution of M. tuberculosis.
  • Developing computational methods for genomic data analysis (including gene prediction, gene expression analysis, and polymorphism discovery)
  • Developing experimental methods for microbial systems identification and analysis, drawing on electrical and mechanical systems identification methods.


A complete list of publications listed chronologically by year.

A complete list of publications by number of citations.