With BU Physics Professor Kirill Korolev, BU Biology Professor Daniel Segrè has been granted a $20,000 research award from the Hariri Institute. The funded project aims to develop a computational tool that can use microbial genomes to predict microbial interactions and ultimately ecosystem dynamics. Beyond prediction, this computational tool will be used to develop design principles for artificial communities and infer microbial interactions in medical and environmental microbiomes. The latter constitutes a major challenge faced by the microbiome research today as interactions are inferred from patterns of co-occurrence in cross-sectional data or temporal correlations in longitudinal data. The computational tool will constrain interaction types using genome-scale metabolic models and remove network motifs inconsistent with the need to co-localize in space. As a result, it will considerably improve the power of sequencing surveys to identify interactions. Congratulations to Professors Segrè and Korolev!

Posted 12 months ago on in Faculty News, News