• Kat J. McAlpine

    Editor, The Brink Twitter Profile

    Kat J McAlpine

    Kat J. McAlpine is editor of The Brink, Boston University’s news site for scientific breakthroughs and pioneering research. Kat has been telling science stories for over a decade, and prior to joining BU’s editorial staff, publicized research at Boston Children’s Hospital, Harvard University’s Wyss Institute for Biologically Inspired Engineering, and the University of Connecticut’s School of Engineering. Profile

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There are 3 comments on Why Some People’s CTE Symptoms Are More Severe Than Others

  1. My son has CTE like symptoms. How do differentiate between CTE related depression and depression not related? He played three sports, including football. Is genetic testing available as described above and how would I contact someone to see how we could have this done? Please respond as soon as you can. I am so appreciative for this research work being done.

    1. I’m so sorry to hear about your son’s depression. Currently CTE can only be definitively diagnosed after death. A major area of our research is the development of criteria to diagnose CTE in life. These criteria may include a lab test or brain image. Unfortunately, diagnostic criteria, brain imaging and blood tests (including genetic tests) are still being investigated and are not yet ready for clinical use. If your son were to be tested for the genetic variation studied in the paper, we would not know how to interpret the results. Having the genetic variant may alter risk of CTE slightly, but other factors such as amount of contact sport play, which symptoms are present, what a brain image looks like, etc. may be much more important. Unfortunately, we just don’t know yet. We would recommend talking to your son’s doctor about your concerns. Regardless of the cause of the depression, there are good symptomatic treatments.

  2. My mom ALS (amyotrophic lateral sclerosis) symptoms started out with a “foot drop” on her left foot. From there her left leg lost all muscle tone and all the entire left leg muscles was almost gone. Also her fingers and thumbs “contract” at times. Left arm is losing muscle tone too,she have been suffering from amyotrophic laterals sclerosis (ALS) disease for the last seven years and had constant pain which really get us worried, especially in her knees, the only treatment for this ALS (amyotrophic lateral sclerosis) is natural organic treatments honestly ,totalcureherbsfoundation .c om has the perfect herbal remedy to all the Motor Neuron Disease including ALS.

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