Age under 65 and History of a Psychiatric or Opioid Use Disorder Are Associated with a Current Prescription Opioid Use Disorder
Prescription opioid abuse is rising in the US, but the prevalence and risk factors among patients treated for chronic nonmalignant pain are uncertain. Researchers conducted telephone interviews diagnostic for an opioid use disorder (OUD) in a random sample of 702 patients from northeastern and central Pennsylvania who had received 4 or more opioid prescriptions for nonmalignant pain in the prior year.
- Thirty-six percent of patients met DSM-IV criteria for lifetime opioid dependence, and 26% met criteria for current dependence.
- Current dependence was associated with age <65 (odds ratio [OR], 1.85), high lifetime score on the Severity of Dependence Scale adapted for opioids (OR, 1.85), major depression (OR, 1.29), psychotropic medication use (OR, 1.73), and history of opioid abuse (OR, 3.81).
- The area-under-the-receiver-operating-characteristic curve of 0.77 meant that the model was 77% accurate in separating this sample of outpatient opioid users into groups with and without opioid dependence.