Severity of Alcohol Problems Predicts Recurrence and Persistence of Alcohol Dependence
This prospective cohort study in the Netherlands enrolled patients with remitted alcohol dependence (AD) (n=253) and current AD (n=135) and followed them for 2 years to identify independent risk factors for AD recurrence and persistence.
- Alcohol dependence recurred in 15% of those with remitted AD and persisted in 41% of those with current AD.
- Past-year total score on the Alcohol Use Disorders Identification Test (AUDIT) at baseline was predictive of AD recurrence and persistence (odds ratio per 5-point increase, 3.6 and 2.1, respectively).
- More severe depressive and anxiety symptoms predicted recurrent AD; however, the great majority of patients reported these symptoms.
- Male gender and high educational attainment predicted persistence of AD.