Alcohol Use and Death from Pancreatic Cancer
Prior research on the association between alcohol use and pancreatic cancer has been confounded by smoking and limited by underpowered studies. In this study, researchers prospectively followed a cohort of 1,030,467 adults aged 30 years or older from 1982–2006. Quantity and frequency of current alcohol use were assessed at baseline. There were 6847 deaths from pancreatic cancer in the cohort over the study period. Multivariable models were used to adjust for demographics and other pancreatic cancer risk factors.
- Compared with nondrinkers, the risk for pancreatic cancer death was higher among participants who drank 3 drinks per day (relative risk [RR], 1.31) and ≥4 drinks per day (RR, 1.14).
- Compared with nondrinkers, the risk for pancreatic cancer death was higher among both never smokers (RR, 1.36) and ever smokers (RR 1.16) who drank ≥3 drinks per day.
- Increased risk at ≥3 drinks per day was primarily seen with liquor use and not with beer or wine use.
- Risk estimates were similar for men and women.