Rat

Rat

CARE AND FEEDING

Cage Dimensions*
# of Adults # of Young Length Width Height
Breeding/Lactation 1 female 8 30 cm 20 cm 20 cm
Growing 10-15 60 cm 50 cm 25 cm
Experimental Varies according to experiment Variable
Feeding Recommendations
Daily Feed Usage Fisher
Ad libitum
Larger Strains ** Water Requirement Begin Dry Food Consumption
Adult Male 12-15 gm 20-35 gm Ad libitum 12 days
Adult Female 12-15 gm 15-25 gm
Preg. & Lactating 30-40 gm 30-55 gm
Females 12-15 gm 15-30 gm
Growing Male 12-15 gm 14-22 gm
Growing Females
Environmental Data
Temp. Humidity Light Litter Material
21-27 °C 45-55% 12 hrs/day Shavings, beet pulp, corn cob,
or commercial bedding

BIOLOGICAL VALUES

Blood Chemical Composition values are for plasma, except where noted
Water Calcium Sodium Chloride Phosphorus Potassium
92-94 gm/100ml 6.2 mEq/L 144 mEq/L 110 mEq/L 5.9 mg/100ml 5.9 mEq/L
Magnesium Cholesterol Glucose Serum Protein Albumin Globulin
2.3 mg/100ml 28-76 mg/100ml 56-76 mg/100ml (whole blood) 6.3 gm/100ml 3.4-4.3 gm/100ml 1.8-2.5 gm/100ml
Oxygen Consumption and Body Temperature
Observed
Weight
Temp-
erature
O2 Con-
sumption
Breathing Rate Heart Beat Adult
Heart Beat Newborn
250 gm 38.2 °C 0.88 mlO2/gm/hr 94/minute
(75-115)
382/minute
(261-600)
161/minute
(81-241)
Hematological Values
Whole Blood Vol. (T-1824 dye) Clotting Time RBC Life Span RBC Diameter RBC Rate of
Sedimentation
58 ml/kg 20 sec. 45-68 days 6.8 microns 0.7-1.8 mm/hr
Blood pH RBC Hematocrit Platelets Hb
7.35 7.2-9.6 106/mm³ 46 ml/100ml 706-796 10³/mm³ 14.8 gm/100ml
Total and Differential White Blood Cell Counts
Leucocytes Neutros Eosinos Basos Lymphos Monos
14.0 10³/mm³ 3.1 10³/mm³ 0.3 10³/mm³ 0.10 10³/mm³ 10.2 10³/mm³ 0.30 10³/mm³

LIFE CYCLE INFORMATION

Weight
Adult Male
Weight
Adult Female
Weight
at Birth
Breeding
Age
Male Breeding Age Estrus
Cycle
300-400 gm 250-300 gm 5-6 gm 100 days
300 gm
100 days
200 gm
5 days
Gestation Weaning Age Litter Size Rebreed After
Parturition
Breeding Life Male Breeding Life Female
20-22 days
21 days avg,
21 days
40-50 gm
8-12 Immediately 1 Year 1 Year
Mating Data: Pair or colony: 1 male, 10 females
* Refer to the “Guide for the Care and use of Laboratory Animals” — NIH Publication No. 85-23, Revised 1985.
Prepared by the Institute of Laboratory Animal Resources, National Research Council, 2101 Constitution Avenue, N.W., Washington, DC 20418
** Depends on Strain of rats. Some Investigators restrict the feed of rats derived from Sprague Dawley, Inc. Levels of 21-22 gr/day for male rats and 16-17 gr/day for female rats are levels of feed restrictions frequently used.

From LabDiets.com