David Tate, PhD
Phone: 617.525.6282
Fax: 617.414.1197
Email: dtate1@partners.org
Location: Robinson-Suite 7800
Background
Dr. David Tate earned his bachelor's degree in psychology and anthropology and his doctoral degree in clinical psychology with a neuropsychology emphasis from Brigham Young University in Provo, Utah. Dr. Tate completed his predoctoral residency in neuropsychology within the Clinical Psychology Training Consortium at Brown Medical School. His post-doctoral training was at The Miriam Hospital in Providence, RI where he completed an NIH/NIDA T32 (DA-13911; Prevention, Diagnosis, and Treatment of HIV and Other Infectious Diseases Among Substance Abusers) fellowship studying the cognitive effects of HIV infection. Dr. Tate joined the faculty at Brown Medical School for one year where he was an Assistant Professor of Research in the Department of Psychiatry and Behavioral Medicine. Currently, Dr. Tate is a research associate of radiology at the Brigham and Women's Hospital and a lecturer at Harvard University Medical School. He has also recently joined the faculty at the Boston University School of Medicine as an adjunct faculty member in the Department of Neurology.
Research Interests
Dr. Tate's research interest has been focused on the interface of state of the art medical imaging (MRI) and behavior. Dr. Tate has participated in several large studies of different neurological diseases, injury, and developmental disorders including Alzheimer's disease, carbon monoxide poisoning, traumatic brain injury, Autism, HIV infection, cardiovascular disease, and post-traumatic stress disorder. Common to each of these studies was the use of structural and functional MRI methods to examine changes in the brain associated with these various neurological disorders and the association these changes have with cognitive performance, behavior, and/or mood. Currently, Dr. Tate has funding to examine three different patient populations using MRI and cognitive testing (HIV, normal aging controls, and mild cognitive impairment). Efforts in these studies are aimed at understanding the evolution and progression of structural imaging changes and how well these changes can be used to examine clinical outcomes in these different patient populations.
ADC Role
Dr. Tate role in the ADC is to provide mentoring in neuroimaging analysis to ADC trainees while supporting collaborative initiatives to examine the progression of common and unique neuroimaging abnormalities among aging patient populations.
Memberships
Dr. Tate is an active member of the International Neuropsychological Society (INS) and the International Society for Magnetic Resonance in Medicine (ISMRM).
Publications
Tate DF, Jefferson AL, Brickman AM, Hoth KF, Gunstad J, Bramley K, Paul RH, Poppas A, Cohen RA. Regional white matter signal abnormalities and cognitive correlates among geriatric patients with treated cardiovascular disease. Brain Imaging and Behavior. (In press) [PDF]
Tate DF, Bigler ED, McMahon W, & Lainhart, JE. (2007). Non-neural Contributions to Measures of Head Circumference in Autistic Children: Occipital-Frontal Circumference Measures and Brain Size Revisited. Neuropediatrics, 38(1): 18-24.
Haley AP, Sweet LH, Gunstad J,Forman DE, Poppas A, Paul RH, Tate DF, Cohen RA. (2007). Verbal working memory and atherosclerosis in patients with cardiovascular disease: an fMRI study. Journal of Neuroimaging, 17(3): 227-233. [PubMed]
Jefferson AL, Tate DF, Poppas A, Brickman AM, Paul RH, Gunstad J, Cohen RA. (2007). Lower cardiac output is associated with greater white matter hyperintensities in older adults with cardiovascular disease. Journal of the American Geriatrics Society, 55(7): 1044-1048. [PDF]
Paul RH, Laidlaw DH, Tate DF, Lee S, Hoth KF, Gunstad J, Zhang S, Lawrence J, Flanigan T. (2007). Neuropsychological and neuroimaging outcome of HIV-associated progressive multifocal leukoencephalopathy in the era of antiretroviral therapy. Journal of Integrative Neuroscience, 6(1): 191-203. [PubMed]
Hoth KF, Tate DF, Poppas A, Forman DE, Gunstad J, Moser DJ, Paul RH, Jefferson AL, Haley AP, Cohen RA. (2007). Endothelial function and white matter hyperintensities in older adults with cardiovascular disease. Stroke, 38(2): 308-312. [PDF]
Zimmerman ME, Brickman AM, Paul RA, Grieve SM, Tate DF, et al., (2006). The relationship between frontal gray matter volume and cognition varies across the healthy adult lifespan. American Journal of Geriatric Psychiatry, 14(10):823-833. [PubMed]
Gunstad J, Poppas A, Smeal, S, Paul R, Tate DF, Jefferson AJ, Forman D, Cohen R. (2006). Elevated BNP levels and reduced cognitive performance in older adults with cardiovascular disease. American Journal of Cardiology, 98(4): 538-540. [PDF]
Brickman AM, Zimmerman ME, Paul RH, Grieve SM, Tate DF, et al., (2006). Regional white matter and neuropsychological functioning across the adult lifespan. Biol Psychiatry, 60(5):444-453. [PDF]
Gunstad J, Cohen RA, Tate DF, Paul RA, Poppas A., Hoth K, MacGregor K, Jefferson AL. (2005). Blood Pressure Variability and White Matter Hyperintensities in Older Adults with Cardiovascular Disease. Blood Pressure, 14(6):353-358. [PubMed]
Paul RH, Gunstand J, Poppas A, Tate DF, Foreman D, Brickman AM, Jefferson AL, Hoth K, & Cohen RA. (2005). Neuroimaging and cardiac correlates of cognitive function among patients with cardiac disease. Cerebrovascular Diseases, 20(2): 129-133. [PubMed]
Paul RH, Haque O, Gunstad J, Tate DF, Grieve SM, Hoth K, Brickman AM, Cohen R, Lange K, Jefferson AL, MacGregor KL, & Gordon E (2005). Subcortical hyperintensities impact cognitive function among a select subset of healthy elderly. Archives of Clinical Neuropsychology, 2005 20(6):697-704. [PDF]
Paul R, Flanigan TP, Tashima K, Cohen R, Lawrence J, Alt E, Tate D, Ritchie C, Hinkin C (2005). Apathy correlates with cognitive function but not CD4 status in patients with human immunodeficiency virus. Journal of Neuropsychiatry and Clinical Neuroscience, 17(1):114-8. [PDF]
Hopkins RO, Tate DF, & Bigler ED. (2005). Anoxia versus traumatic brain injury: The amount of tissue loss not etiology, alters cognitive and emotional functioning. Neuropsychology, 19 (2), 233-242. [PubMed]
Rice SA, Bigler ED, Cleavinger HB, Tate DF, et al., (2005). Macrocephaly, corpus callosum morphology, and autism. Journal of Child Neurology. 20(1):34-41. [PubMed]
Tate D, Paul RH, Flanigan TP, Tashima K, Nash J, Adair C, Boland R, Cohen RA. (2003). The impact of apathy and depression on quality of life in patients infected with HIV. AIDS Patient Care STDS, 17(3): 115-120.
Bigler ED, Tate DF,…Welsh-Bohmer KA. (2002). Dementia, asymmetry of temporal lobe structures, and apolipoprotein E genotype: Relationships to cerebral atrophy and neuropsychological impairment. J International Neuropsychological Society, 8(7): 925-933. [PDF]
Bigler ED, Tate DF. (2001). Brain volume, intracranial volume, and dementia. Investigative Radiology, 36(9): 539-536.
Tate DF, Bigler ED. (2000). Fornix and hippocampal atrophy in traumatic brain injury. Learning and Memory, 7(6): 442-446.
View Dr. Tate's Biosketch
|
|