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Alpaslan Dedeoglu, MD, PhDAssistant Professor of Neurology Phone: 857-364-6783Fax: 857-364-4540 Email: dedeoglu@bu.edu Location: Boston VA Medical Center BackgroundDr. Alpaslan Dedeoglu received his MD from the Istanbul University School of Medicine and completed a pharmacology program at the Marmara University in 1992. During and after his pharmacology program he worked at the University of Arizona, Ohio State University, and Massachusetts General Hospital; he then joined Boston University in 2000. Dr. Dedeoglu's major research interests are neuroanatomy, neuropathology, and the neurochemistry of animal models of neurodegenerative disorders. His labs are located at the Bedford VAMC. Dr. Dedeoglu is the PI of several ongoing projects that are funded by the NIH, VA, and private foundations. Research InterestsDr. Dedeoglu's research interests include the following: neuroanatomy, immunocytochemistry, histochemistry of the brain, neuropathological and neurochemical basis of neurological disorders, and animal models of neurological diseases. He also works with therapeutic trials in rodent models of neurodegenerative disorders. ADC RoleDr. Dedeoglu is the Co-Director of the Translational Animal Core together with Dr. Lee Goldstein. Awards/MembershipsDr. Dedeoglu has received various awards: Sandoz Pharmacology Science Award (1989), Eczacibasi Scientific Research and Medicine Encouragement Award (1992), Alzheimer’s Disease Core Center pilot award (2001-2002). “Therapeutic Strategies in a Mouse Model of AD” Principal Investigator, Alzheimer’s Association New Investigator Award (2002-2004)” Anti-inflammatory Therapy in a Mouse Model of AD“ Principal Investigator, Merit Award (2004-2011) “Therapeutic Strategies in a Transgenic Model of AD”, Principal Investigator, R21 NIA (2005-2007), Integrated Neuroimaging and Pathology of Alzheimer Mice”, Principal Investigator, Merit Award (2005-2008) “Integrated neuroimaging and neuropathological study of exercise in ALS” Dr. Dedeoglu is a member of the Boston Society of Neurology and Psychiatry and the Society for Neuroscience. Recent PublicationsPeer-reviewed publications of Dr. Dedeoglu’s work include the following (selected from a list of 40): Dedeoglu A, Choi JK, Cormier K, Kowall NW, Jenkins BG. Magnetic resonance spectroscopic analysis of Alzheimer disease mouse brain that express mutant human APP shows altered neurochemical profile. Brain Research, 2004; 1012: 60-65. [PDF] Jenkins BG, Andreassen OA, Dedeoglu A, Leavitt B, Hayden M, Borchelt D, Ross CA, Detloff P, Ferrante RJ, Beal MF. Effects of CAG repeat length on cerebral metabolism in transgenic mouse models of Huntington’s disease. Journal of Neurochemistry, 2005; 95(2):553-562. [PDF] Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Experimental Gerontology, 2004; 39:1641-1649. [PDF] Choi J-K, Dedeoglu A, Jenkins BG. Application of MR spectroscopy to mouse models of neurodegeneration. NMR in Biomedicine, 2007; (20):1–22. [PDF] |
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