The grandfather and granddaughterHealth Outreach Program for the Elderly (HOPE) Study

The Health Outreach Program for the Elderly (HOPE) study, funded by the National Institute on Aging (NIA), is a long-term study of memory and aging. This study is designed to help us improve our understanding of how memory and other thinking abilities change in people as they age, evaluating persons with and without memory problems throughout their lives. The HOPE study also serves as a registry of research participants to help other researchers who are studying normal aging and Alzheimer’s disease. The results of the study provide valuable information that will assist researchers who are working toward finding causes and treatments for Alzheimer’s disease and related memory impairment.

You may be eligible to participate if you:

  • Are 65 years of age or older without memory concerns or
  • Are 50 years or older with memory concerns
  • Have a caregiver or study partner who can accompany you to your annual study visit

Since little is known about Alzheimer’s disease in African American families, a priority of this project is to enroll African Americans. This research will help ensure African Americans benefit from new developments in diagnosis and treatment.

What happens during the study?

Participants will be asked questions about family and medical history, and will undergo some tests of memory and concentration. A physical and neurological exam will be performed as well. Participants will be asked to return yearly for a follow up visit. A caregiver or study partner, someone who knows the participant well, will be asked to accompany the participant at each yearly visit.

Brain Tissue Donation: Participants in the HOPE study are asked to consider donating brain tissue after death. Research using brain tissue helps scientists discover treatments for Alzheimer’s disease and other memory-related disorders. The results of the brain examination will be made available to your family.

Where is this study taking place?

Boston University Medical Center
Boston University Neurology Associates (Weymouth)

Meet the team

What if I am an investigator interested in accessing the HOPE registry for research participants?

Please refer to the Information for Investigators page.

More information

Please call (617) 358-5382 or email for more information and to participate.