Actively Recruiting Studies and Clinical Trials

 

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Our Center supports a wide variety of Alzheimer’s disease-related research. If you are interested in participating in one of our studies, please call 617-414-1077 or email joinADC@bu.edu for more information.

 

Detection and diagnosis

Health Outreach Program for the Elderly (HOPE)

The HOPE study is the BU ADC main registry of participants. People who join HOPE attend a yearly visit in which their memory and thinking abilities are evaluated. They also participate in other BU ADC affiliated studies.

Eligibility: Healthy adults, MCI, AD

Research Study of Former Contact Sport Athletes

This study is attempting to determine which factors increase a person’s risk of developing CTE and learning how to diagnose it in living patients

Eligibility: Former contact sport athletes

Amylin, Amyloid-beta Peptide, and Alzheimer’s disease

The goal of this study is to develop a blood test that can be used to diagnose and possibly treat patients with MCI or dementia due to Alzheimer’s disease.

Eligibility: Healthy Adults, MCI, AD

 

Clinical Trials

The A4 Study

This clinical trial is examining the effects of Solanezumab in patients with memory complaints, but who have not been diagnosed with MCI or AD.

Eligibility: Pre-clinical memory complaints

BAN2401 for early Dementia and Mild Cognitive Impairment

This clinical trial is examining the effects of BAN2401 in patients with MCI and very early AD.

Eligibility: MCI, AD

The NOBLE Study

This clinical trial is examining the effects of an oral medication on those with mild to moderate AD currently on Aricept (Donepezil)

Eligibility: Moderate AD

 

Improving Thinking and Memory

The Memory Benefits of Sleep in Healthy Young, Elderly, and Mild AD Subjects

The goal of this study is to analyze the effects of sleep on memory processing.

Eligibility: Healthy Adults

Effects of Parkinson’s Disease on Perception and Gait

This study looks at neurological changes associated with Parkinson’s and the relationships between basic vision, visuospatial abilities and daily function.

Eligibility: Healthy Adults

Memory in Alzheimer’s Disease and Mild Cognitive Impairment

This research study seeks to understand why patients with Alzheimer’s disease frequently remember things that did not happen.

Eligibility: Healthy Adults, MCI, AD

Cardiovascular Integrity Risk for Cognitive Decline in Aging (CIRCA)

CIRCA is examining how brain structures relate to cognitive changes and how risk factors for cerebrovascular disease may affect individuals with and without MCI.

Eligibility: Healthy Adults, MCI

 

Caregiving

Alzheimer’s Association Dementia Care Coordination Project

This study will evaluate approaches to care coordination and education for those with AD or other dementias.

Eligibility: All forms of dementia (i.e. AD, PD, FTD, etc.), MCI

Emotional Perception, Neuropsychiatric Symptoms and Caregiver Experience in AD

Researchers are examining how changes in emotional perception in people with dementia due to Alzheimer’s disease impact the experience of their caregivers.

Eligibility: Healthy Adults, AD

Health Pathways (Caregivers)

The Health Pathways study looks at how caring for a person with dementia affects physical and emotional health.

Eligibility: Healthy Adults

 

Other Studies

Mitochondrial Abnormalities and Repair in Psychiatric Illness

This study aims to learn about the structure and function of cells and mitochondria of people with brain illness.

Eligibility: Healthy Adults, AD

Aerobic Exercise, Neurotrophins, and fMRI

This study is investigating the effects of exercise and cardiovascular fitness on cognitive processes, brain function, and levels of certain proteins in the blood.

Eligibility: Are between 18-35 or 55-85 years old

Are a healthy, sedentary adult

 

For More Information on Alzheimer’s Disease and Research

Alzheimer’s Association National Chapter
Alzheimer’s Association MA/NH Chapter
National Institute on Aging’s Alzheimer’s Disease Education and Referral Center
Boston Medical Center Memory Disorder’s Clinic
AlzForum
Clinical Trials.gov
Alzheimers.net