Russ Huber

Background

Dr. Huber completed his undergraduate studies at the University of California Santa Cruz and earned a PhD degree in Biophysics at the University of California San Francisco. He earned his MD from the Harvard-MIT Health Science and Technology program. He completed residency training in Anatomic Pathology and fellowship training in Neuropathology at the University of Washington. Dr. Huber is an Assistant Professor of Neurology at Boston University and is the director of the PTSD Brain Bank at the Jamaica Plain Veterans Administration. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy and Framingham Heart Study.

Research Interests

Dr. Huber’s research interests center on the relationship between neurotrauma and neurodegenerative diseases, with a primary focus on the blood-brain barrier and neuroinflammation. Much of his current work centers on astrocytic injury in repetitive neurotrauma and the accumulation of tau pathology. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, Framingham Heart Study, as well as the PTSD brain bank.

Awards and Memberships

Dr. Huber is a member of the Society for Neuroscience, the College of American Pathologists, the American Society of Clinical Pathologists, and the International Society for Biological and Environmental Repositories.

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Recent Publications

Click here for a full list of publications

Cherry, J.D., Tripodis, Y., Alvarez, V.E., Huber, B., Kiernan, P.T., Daneshvar, D.H., Mez, J., Montenigro, P.H., Solomon, T.M., Alosco, M.L. & Stern, R.A., 2016. Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy. Acta Neuropathologica Communications, 4(1), p.112.

Huber, B.R., Meabon, J.S., Hoffer, Z.S., Zhang, J., Hoekstra, J.G., Pagulayan, K.F., McMillan, P.J., Mayer, C.L., Banks, W.A., Kraemer, B.C., Raskind, M.A., McGavern, D.B., Peskind, E.R. & Cook. D. G. Blast exposure causes dynamic microglial/macrophage responses and microdomains of brain microvessel dysfunction. Neuroscience, 2016:319, 206-220

McKee, A.C., Alosco, M.L. & Huber, B.R., 2016. Repetitive head impacts and chronic traumatic encephalopathy. Neurosurgery clinics of North America, 27(4), pp.529-535.

Huber, B.R., Alosco, M.L., Stein, T.D. & McKee, A.C., 2016. Potential long-term consequences of concussive and subconcussive injury. Physical medicine and rehabilitation clinics of North America, 27(2), pp.503-511.

Meabon, J.S., Huber, B.R., Cross, D.J., Richards, T.L., Minoshima, S., Pagulayan, K.F., Li, G., Meeker, K.D., Kraemer, B.C., Petrie, E.C., Raskind, M.A., Peskind, E.R. & Cook, D.G. Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Sci. Transl. Med, 2016:8(321), pp.321ra6-321ra6.

Peskind, E.R., Petrie, E.C., Li, G., Cross, D., Yarnykh, V., Richards, T., Minoshima, S., Mayer, C., Pagulayan, K., Huber, B.R. and Meabon, J., Raskind, M.R., Zhang, J. & Cook, D.G. Neuroimaging and cerebrospinal fluid biomarkers in iraq and afghanistan veterans: Effects of deployment and blast concussion mild traumatic brain injury. Alzheimers Dement, 2015:11(7), p.P513.

Meabon, J.S., deLaat R., Ieguchi K., Serbzhinsky D., Hudson, M. P., Huber, B. R., Wiley, J. C. & Bothwell, M. Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling, Mol. Cell Neurosci. 2016:70 1–10

Huber, B. R., Meabon, J. S., Martin, T. J., Mourad, P. D., Bennett, R., Kraemer, B. C., Cernak, I., Petrie, E. C., Emery, M. J., Swenson, E. R., Mayer, C., Mehic, E., Peskind, E. R. & Cook, D. G. Blast exposure causes early and persistent aberrant phospho- and cleaved-tau expression in a murine model of mild blast-induced traumatic brain injury. J Alzheimers Dis. 2013:37(2) 309-323.

Mayer, C. L., Huber, B. R. & Peskind, E. Traumatic brain injury, neuroinflammation and post traumatic headaches. Headache 2013:53(9), 1523-1530.