BU AD & CTE Current News
The cutting-edge work of our center and researchers receives attention from both regional and national media. Check out our latest headlines and keep up to date with notable Alzheimer’s news from around the globe!
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BU ADC News
2018 Alzheimer’s Association Spring Research Forum
The 2018 Alzheimer’s Association was held on April 4th, 2018. The discussion of past, present and future research on Alzheimer’s Disease was discussed. Our very own, Dr. Andrew Budson, spoke about strategies we can do to keep our memory and thinking strong.
Mr. Gussis has been poked and prodded, tested on treadmills and with memory quizzes, served fatty meals followed by blood tests. His memory, cognition, and emotional regulation have been measured and his brain waves monitored. And he went through it all for science.
“There is a lot of hope in this field now, and that’s because of people like Mr. Gussis who are willing to come and participate in studies.” – Eric Steinberg, project manager for the Health Outreach Program for the Elderly (HOPE) study, conducted by the BU Alzheimer’s Disease Center.
Memory lapses: MED prof’s book tells when to worry, when not to
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Dr. Andrew Budson, director of the Alzheimer’s Disease Center Education Core and associate chief of staff for education at the Veterans Affairs Boston Healthcare System, wants to help people worry less about their memories—and understand more about what’s happening inside their brains and what they can do about it. His book is intended to help lay readers recognize signs of memory problems that are more than just part of normal aging. He describes the markers of mild cognitive impairment, dementia, Alzheimer’s, and other neurodegenerative diseases and emphasizes the importance of getting tested as early as possible if these markers are present.
BU ADC Investigator, Dr. Karin Schon was Awarded an Alzheimer’s Association Grant on December 20th, 2017
This funding will enable Dr. Schon to examine whether chronic stress due to daily and lifetime experiences of discrimination related to racial minority status — racism — negatively affects brain function in two subgroups of Black seniors that differ in their exposure to racism.
BU ADC Investigator, Dr. Michael Alosco was Awarded an Alzheimer’s Association Grant on October 24th, 2017
Dr. Michael Alosco, PhD, a BU ADC Investigator, along with Dr. Lin Alexander, PhD, who is the head investigator at the primary study site at Brigham and Woman Hospital, received a new Alzheimer’s Association Grant. Their study will use enhanced arterial spin labeling (eASL) and magnetic resonance (MR) two-dimensional J-resolved spectroscopy (2D-JPRESS) to test whether individuals at high risk for chronic traumatic encephalopathy (CTE) exhibit patterns of cerebral blood flow (CBF) and glutamate (Glu) metabolism that are distinct from aging and Alzheimer’s disease (AD) dementia. This study will further examine whether CBF and Glu may be involved in the pathogenesis of CTE through testing their correlations with PET p-tau and clinical function.
BU ADC staff, faculty, and their families came together and supported the 2017 Alzheimer’s Association Walk on September 24th, 2017
BU Alzheimer’s Disease Center Wins $5.4 Million NIH Grant
Will fund research on early diagnostics, genetic risk factors, interventions
The National Institute on Aging, part of the National Institutes of Health (NIH), has awarded Boston University’s Alzheimer’s Disease Center a three-year, $5.4 million grant to continue its research into interventions that will reduce the human and economic costs of Alzheimer’s disease and its related conditions, which includes chronic traumatic encephalopathy.
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Photo Credit: Andrew Budson directs the Alzheimer’s Disease Center’s National Institutes of Health–funded efforts to educate clinicians and the public in better understanding the disease and related disorders as well as to encourage people to participate in research. Photo by Cydney Scott
Drug Shows Promise for Treating, Detecting Alzheimer’s
“A single injection of pramlintide into our patients was well tolerated and reduced the amyloid burden as well as lowered the concentrations of amyloid-β peptides, a major component of AD in the brain,” explained corresponding author Wendy Qiu, MD, PhD, associate professor of psychiatry and pharmacology and experimental therapeutics at Boston University School of Medicine.
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Study identifies 2 new genes responsible for Alzheimer’s disease among African-Americans
(Boston)–Researchers have identified two new genetic risk factors for Alzheimer’s disease (AD) among African Americans.
The findings, which appear online in the journal Alzheimer’s and Dementia, may lead to the development of new therapies specifically targeting those genes.
“There are currently no medications for AD that slow or stop the progression of the disease. Genes that increase risk for AD are potential targets for new disease-modifying AD drug therapies. Our study identifies two potentially “drugable” targets,” explains corresponding author Jesse Mez, MD, MS, assistant professor of neurology at BUSM and associate director of the Boston University Alzheimer’s Disease & CTE Center Clinical Core.
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Dr. Andrew Budson is currently the Associate Chief of Staff for Education at VA Boston Healthcare System and Associate Director of the Education Core and Associate Director for the Boston University Alzheimer’s Disease Center. He is also the principal investigator of the Center for Translational Cognitive Neuroscience at VA Boston, where his research seeks to understand false memories in Alzheimer’s disease, and different non-invasive methods that could improve memory in patients with Alzheimer’s disease.
Dr. Katherine Turk is Awarded an Alzheimer’s Association Clinical Fellowship Award
Dr. Katherine Turk, an instructor in Neurology at BUSM and physician scientist pursuing fellowship training at VA Boston has been awarded the Alzheimer’s Association Clinical Fellowship Award for her project in the lab of Dr. Andrew Budson, using event related potentials to diagnose Alzheimer’s disease in the clinic. The funding of $150,000 over three years allows extension of the project to include Amyloid PET scans for participants as well as quantitative MRI techniques. Ultimately the project will compare diagnosis of Alzheimer’s disease using event related potential techniques to Amyloid PET techniques as a gold standard.
Dr. Tsuney Ikezu Receives an Award from the Alzheimer’s Association for his Research
Tsuneya Ikezu, MD, PhD, professor of pharmacology & experimental therapeutics and neurology at Boston University School of Medicine (BUSM), recently received the Alzheimer’s Association’s Inge Grundke-Iqbal Award for Alzheimer’s Research. The award was presented at the Alzheimer’s Association International Conference® 2016 in Toronto.
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$1.49 Million NIH Grant to fun Start up that develops therapeutics to protect against Alzheimer’s Disease
“She came home from her lab one day and said she wanted to start a company to develop novel therapeutics to protect against Alzheimer’s disease.”
Click here to learn more about their journey.
Click on the image above to learn more about BU ADC research
“I think the goal of medicine is to reduce the pain of mankind. I strongly believe that,” says Dr. Qiu, BU ADC faculty member.
Alzheimer’s ravages the minds of over 40 million victims worldwide. Join scientists as they untangle the cause of this tragic illness, and go behind the scenes of major drug trials to discover the therapies that may slow and even prevent the disease.
PBS Nova “Can Alzheimer’s Be Stopped?” Premieres Wednesday, April 13, 2016 at 9pm ET/8C on PBS.
Want to make a difference in the fight against Alzheimer? To see if you qualify contact Boston University Alzheimer’s Disease Center, 617-414-1077. Now is the time!
Click here to learn more about the A4 Study.
Gift Recognizes Family’s Struggle with Alzheimer’s
“We all wanted to honor my father, but we also wanted to do something for BU, since he had so loved it.”
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Dr. Sudha Seshadri, an investigator at Boston University Alzheimer’s Disease Center and Framingham Heart Study, along with colleagues published a paper in The New England Journal of Medicine. The paper is titled, Incidence of Dementia over Three Decades in the Framingham Heart Study.
January 14th, 2016
Venue: VA Boston Healthcare System
Dr. Jesse Mez, Associate Director of the Clinical Core at Boston University Alzheimer’s Disease Center was presented with a check from the Alzheimer’s Association to support his research in genetics.
Professor of Neurology & Pathology, Director, Neuropathology Core
Awarded the Boston University School of Medicine Jack Spivack Excellence in Neurosciences Award of 2016.
$ 16 Million Dollar Grant Awarded to Dr. Robert Stern
Boston University Alzheimer’s Disease Center (BU ADC)/Chronic Traumatic Encephalopathy (CTE) Program is excited to announce that Dr. Robert Stern, professor of neurology, neurosurgery, and anatomy and neurobiology at BU School of Medicine (MED), and clinical core director for the BU ADC/CTE Program has been awarded a $16 million dollar grant from the National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) to develop methods for diagnosing CTE during life.
Stern describes the project as “the biggest study of CTE in living subjects to date, in terms of the scope of the science, the number of participants, the breadth and depth and size of the group of investigators, and the amount of the grant.”
And because CTE shares certain features of Alzheimer’s and other neurodegenerative diseases, says Stern, the study will benefit research beyond the field of CTE. “We expect what we learn from this project will have a tremendous impact on the understanding of those other diseases,” he notes.
Published Findings From Very First NINDS/NIBIB Consensus Hosted at Boston University Alzheimer’s Disease Center
December 15th, 2015
Dr. Ann McKee, Neuropathology Core Director and Associate Director of the Boston University Alzheimer’s Disease Center/ CTE Program along with colleagues published a paper introducing evidence from their first NINDS/NIBIB consensus meeting that defined neuropathological criteria for the diagnosis of chronic traumatic encephalopathy.
Study Helps Veternas Age
There is good news and bad news when it comes to aging wisely. First, the bad news: no magic pill portion can keep you physicaly and mentally robust into your golden years. The good news is Veterans have Dr. Maureen O’Connor on their side, helping them understand what normal aging is like providing tips to keep their brain health at any age
Groundbreaking documentary on Art and Alzheimer’s airs nationwide on public television in 2015
I Remember Better When I Paint shows how the creative arts can enhance the quality of life for people with Alzheimer’s. The program continues to broadcast on public television stations nationwide in 2015, in particular at the end of October and also in November which is National Alzheimer’s Awareness Month in the US.
Leading doctors and neurologists explain how parts of the brain can be spared and discuss the life-enriching benefits of these new approaches. Among these experts is, Dr. Robert Stern, Boston University Alzheimer’s Disease Center Clinical Core Director.
The Wingate Residences Announces Partnership with Boston University School of Medicine and Its Alzheimer’s Disease and CTE Center (BU ADC)
October 5, 2015, Needham, MA – The Wingate Residences, a leading senior living community located on the Wingate at Needham campus in Needham, Massachusetts, today announced its partnership with Boston University School of Medicine and their Alzheimer’s Disease and CTE Center (BU ADC). This partnership aligns with Wingate’s Memory Care 360˙ program mission to enhance the lives of seniors coping with Alzheimer’s and dementia-related diseases. Click Here to Learn More
Dr. Jesse Mez Receives an Alzheimer’s Association Grant Award
Dr. Jesse Mez, Associate Director of the Clinical Core at Boston University Alzheimer’s Disease Center was presented with an Alzheimer’s Association research grant last night at the Simons Symposium. This event was held by the Alzheimer’s Association and was open to the community.
Dudley Allen Sargent Lecture: Dr. Stern attracts 300
Dr. Stern was invited to give a lecture on CTE at Sargent College on October 1st. Appropriate for rehabilitation school setting, the presentation focused on the long term effects of repetitive head injuries. As a major public health concern for our country, the brain disease CTE can lead to many health concerns. The importance of protective one’s head is often underestimated, especially when it comes to America’s favor its past times. Dir. Stern’s goal was to raise awareness and provide updates on what his research is work towards.
A Light at the End of the Tunnel for Alzheimer’s? Dr. Stern says it may be coming
Excerpt: “Stern said that T-817MA could also go a step further and protect brain cells from destruction of Alzheimer’s disease, which leads to dementia. ‘The changes in the brain in Alzheimer’s disease start maybe 20 years before the first symptoms and then get worse and worse as the disease gets further along,” said Stern. “If this drug would work, it would slow that progression so the person would be able to maintain a much better quality of life without deteriorating.’ Stern said that would be a game changer for patients and their caregivers.”
Exercise and Social Networking: Two Strategies to Work Out your Brain
CBS Boston News
Excerpt: “Doing something surrounded by people, interacting with people. The research does suggest that that has some ability to keep the brain healthy as we get older. Anything is better than nothing. Anything is better than isolation.