Robert Stern, PhD

Professor of Neurology, Neurosurgery, and Anatomy &  Neurobiology
Director, Alzheimer’s Disease Center Clinical Core
Director of Clinical Research, Chronic Traumatic Encephalopathy Center

View Dr. Robert A. Stern’s Lab Website

Hear Dr. Stern discuss his paper in Neurology on WBUR’s Radio Boston

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View Dr. Robert A. Stern’s Biographical Summary
View Dr. Robert A. Stern’s Curriculum Vitae

 

 

Dr. Robert Stern is Professor of Neurology, Neurosurgery, and Anatomy and Neurobiology at Boston University School of Medicine, where he is also Director of the Clinical Core of the BU Alzheimer’s Disease Center (one of only 27 centers funded by the National Institutes of Health, NIH), and Director of Clinical Research for the BU Chronic Traumatic Encephalopathy (CTE) Center.  A major focus of his research involves the long-term effects of repetitive brain trauma in athletes, including the neurodegenerative disease, CTE.  He has funding from NIH and the Department of Defense for his work on developing methods of detecting and diagnosing CTE during life, as well as examining potential genetic and other risk factors for this disease.  His other major areas of funded research include the assessment and treatment of Alzheimer’s disease, the cognitive effects of chemotherapy in the elderly, thyroid-brain relationships, and driving and dementia.  Dr. Stern has also published on various aspects of cognitive assessment and is the senior author of many widely used neuropsychological tests, including the Neuropsychological Assessment Battery (NAB).  Dr. Stern has received several NIH and other national grants, has published over 250 journal articles, chapters, and abstracts, and is a Fellow of both the American Neuropsychiatric Association and the National Academy of Neuropsychology.  He is on several editorial boards and is on the Medical and Scientific Advisory Boards of the MA/NH Chapter of the Alzheimer’s Association and Concussion Legacy Foundation, and is also a member of the Mackey-White Traumatic Brain Injury Committee of the NFL Players Association. Dr. Stern has testified before the US Senate Special Committee on Aging. He appears frequently in national and international print and broadcast media for his work on CTE and AD.  He also appears in the feature length documentaries, “League of Denial” (PBS Frontline, 2013), “Head Games” (2012), and “I Remember Better When I Paint” (2009).

Background 

Dr. Stern received his undergraduate degree from Wesleyan University and his Masters and Ph.D. degrees in Clinical Psychology from the University of Rhode Island. He completed his neuropsychology internship training at the Boston VA Medical Center, under the supervision of Dr. Edith Kaplan, and his postdoctoral fellowship training in both neuropsychology and psychoneuroendocrinology at the University of North Carolina (UNC) School of Medicine. He was on the faculty at UNC from 1990-1993, where he was Associate Director of the NIMH-funded Mental Health Clinical Research Center and Director of the Neurobehavioral Assessment Core. He then joined the faculty at Brown Medical School, where he was Associate Professor of Psychiatry and Neurology, as well as Director of Neuropsychology and the Memory and Cognitive Assessment Program at Rhode Island Hospital. He was also directed the Brown Clinical Neuropsychology Internship Training Program.  In 2004, Dr. Stern joined the Boston University School of Medicine’s Department of Neurology as an Associate Professor. He was promoted to Professor of Neurology and Neurosurgery in 2011  and was then appointed to professor of Neurology, Nuerosurgery, and Neurobiology, in 2014 . Dr. Stern and his wife, Susan Ryerson, live in Needham, MA and have four children.

Recent Publications

Click here for full list of publications.

Curriculum Vitae

  1. Chapman KR, Bing-Canar H, Alosco ML, Steinberg EG, Martin B, Chaisson C, Kowall N, Tripodis Y, Stern RA. Mini Mental State Examination and Logical Memory scores for entry into Alzheimer’s disease trials. Alzheimers Res Ther. 2016; 8(1):9. PMID: 26899835.
    View in: PubMed
  2. Stern RA, Tripodis Y, Baugh CM, Fritts NG, Martin BM, Chaisson C, Cantu RC, Joyce JA, Shah S, Ikezu T, Zhang J, Gercel-Taylor C, Taylor DD. Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy. J Alzheimers Dis. 2016 Feb 10; 51(4):1099-109. PMID: 26890775.
    View in: PubMed
  3. Koerte IK, Hufschmidt J, Muehlmann M, Tripodis Y, Stamm JM, Pasternak O, Giwerc MY, Coleman MJ, Baugh CM, Fritts NG, Heinen F, Lin A, Stern RA, Shenton ME. Cavum Septi Pellucidi in Symptomatic Former Professional Football Players. J Neurotrauma. 2016 Feb 15; 33(4):346-53. PMID: 26414478.
    View in: PubMed
  4. Mez J, Solomon TM, Daneshvar DH, Murphy L, Kiernan PT, Montenigro PH, Kriegel J, Abdolmohammadi B, Fry B, Babcock KJ, Adams JW, Bourlas AP, Papadopoulos Z, McHale L, Ardaugh BM, Martin BR, Dixon D, Nowinski CJ, Chaisson C, Alvarez VE, Tripodis Y, Stein TD, Goldstein LE, Katz DI, Kowall NW, Cantu RC, Stern RA, McKee AC. Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study. Alzheimers Res Ther. 2015; 7(1):62. PMID: 26455775.
    View in: PubMed
  5. Stern RA, Hennessey JV. Screening for Thyroid Dysfunction. Ann Intern Med. 2015 Oct 6; 163(7):564. PMID: 26436624.
    View in: PubMed
  6. Stamm JM, Koerte IK, Muehlmann M, Pasternak O, Bourlas AP, Baugh CM, Giwerc MY, Zhu A, Coleman MJ, Bouix S, Fritts NG, Martin BM, Chaisson C, McClean MD, Lin AP, Cantu RC, Tripodis Y, Stern RA, Shenton ME. Age at First Exposure to Football Is Associated with Altered Corpus Callosum White Matter Microstructure in Former Professional Football Players. J Neurotrauma. 2015 Nov 15; 32(22):1768-76. PMID: 26200068.
    View in: PubMed
  7. Maroon JC, Bailes J, Collins M, Lovell M, Mathyssek C. Age of first exposure to football and later-life cognitive impairment in former NFL players. Neurology. 2015 Sep 15; 85(11):1007. PMID: 26370191.
    View in: PubMed
  8. Stern RA, Stamm JM. Author Response. Neurology. 2015 Sep 15; 85(11):1008-10. PMID: 26623466.
    View in: PubMed
  9. Koerte IK, Mayinger M, Muehlmann M, Kaufmann D, Lin AP, Steffinger D, Fisch B, Rauchmann BS, Immler S, Karch S, Heinen FR, Ertl-Wagner B, Reiser M, Stern RA, Zafonte R, Shenton ME. Cortical thinning in former professional soccer players. Brain Imaging Behav. 2015 Aug 19. PMID: 26286826.
    View in: PubMed
  10. Koerte IK, Lin AP, Muehlmann M, Merugumala S, Liao H, Starr T, Kaufmann D, Mayinger M, Steffinger D, Fisch B, Karch S, Heinen F, Ertl-Wagner B, Reiser M, Stern RA, Zafonte R, Shenton ME. Altered Neurochemistry in Former Professional Soccer Players without a History of Concussion. J Neurotrauma. 2015 Sep 1; 32(17):1287-93. PMID: 25843317.
    View in: PubMed
  11. Stein TD, Montenigro PH, Alvarez VE, Xia W, Crary JF, Tripodis Y, Daneshvar DH, Mez J, Solomon T, Meng G, Kubilus CA, Cormier KA, Meng S, Babcock K, Kiernan P, Murphy L, Nowinski CJ, Martin B, Dixon D, Stern RA, Cantu RC, Kowall NW, McKee AC. Beta-amyloid deposition in chronic traumatic encephalopathy. Acta Neuropathol. 2015 Jul; 130(1):21-34. PMID: 25943889.
    View in: PubMed
  12. Koerte IK, Lin AP, Willems A, Muehlmann M, Hufschmidt J, Coleman MJ, Green I, Liao H, Tate DF, Wilde EA, Pasternak O, Bouix S, Rathi Y, Bigler ED, Stern RA, Shenton ME. A review of neuroimaging findings in repetitive brain trauma. Brain Pathol. 2015 May; 25(3):318-49. PMID: 25904047.
    View in: PubMed
  13. Feke GT, Hyman BT, Stern RA, Pasquale LR. Retinal blood flow in mild cognitive impairment and Alzheimer’s disease. Alzheimers Dement (Amst). 2015 Jun; 1(2):144-51. PMID: 27239502.
    View in: PubMed
  14. Lin AP, Ramadan S, Stern RA, Box HC, Nowinski CJ, Ross BD, Mountford CE. Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy. Alzheimers Res Ther. 2015; 7(1):13. PMID: 25780390.
    View in: PubMed
  15. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. PMID: 25531812.
    View in: PubMed
  16. Stamm JM, Bourlas AP, Baugh CM, Fritts NG, Daneshvar DH, Martin BM, McClean MD, Tripodis Y, Stern RA. Age of first exposure to football and later-life cognitive impairment in former NFL players. Neurology. 2015 Mar 17; 84(11):1114-20. PMID: 25632088.
    View in: PubMed
  17. Montenigro PH, Corp DT, Stein TD, Cantu RC, Stern RA. Chronic traumatic encephalopathy: historical origins and current perspective. Annu Rev Clin Psychol. 2015; 11:309-30. PMID: 25581233.
    View in: PubMed
  18. Riley DO, Robbins CA, Cantu RC, Stern RA. Chronic traumatic encephalopathy: contributions from the Boston University Center for the Study of Traumatic Encephalopathy. Brain Inj. 2015; 29(2):154-63. PMID: 25587744.
    View in: PubMed
  19. Baugh CM, Kiernan PT, Kroshus E, Daneshvar DH, Montenigro PH, McKee AC, Stern RA. Frequency of head-impact-related outcomes by position in NCAA division I collegiate football players. J Neurotrauma. 2015 Mar 1; 32(5):314-26. PMID: 25155288.
    View in: PubMed
  20. Montenigro PH, Stern RA. Author response. Neurology. 2014 Nov 18; 83(21):1992-3. PMID: 25562087.
    View in: PubMed
  21. Andrikopoulos J. Clinical presentation of chronic traumatic encephalopathy. Neurology. 2014 Nov 18; 83(21):1991-2. PMID: 25404647.
    View in: PubMed
  22. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. PMID: 25199842.
    View in: PubMed
  23. Montenigro PH, Baugh CM, Daneshvar DH, Mez J, Budson AE, Au R, Katz DI, Cantu RC, Stern RA. Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome. Alzheimers Res Ther. 2014; 6(5):68. PMID: 25580160.
    View in: PubMed
  24. Baugh CM, Robbins CA, Stern RA, McKee AC. Current understanding of chronic traumatic encephalopathy. Curr Treat Options Neurol. 2014 Sep; 16(9):306. PMID: 25023937.
    View in: PubMed
  25. Mandelblatt JS, Stern RA, Luta G, McGuckin M, Clapp JD, Hurria A, Jacobsen PB, Faul LA, Isaacs C, Denduluri N, Gavett B, Traina TA, Johnson P, Silliman RA, Turner RS, Howard D, Van Meter JW, Saykin A, Ahles T. Cognitive impairment in older patients with breast cancer before systemic therapy: is there an interaction between cancer and comorbidity? J Clin Oncol. 2014 Jun 20; 32(18):1909-18. PMID: 24841981.
    View in: PubMed
  26. Robbins CA, Daneshvar DH, Picano JD, Gavett BE, Baugh CM, Riley DO, Nowinski CJ, McKee AC, Cantu RC, Stern RA. Self-reported concussion history: impact of providing a definition of concussion. Open Access J Sports Med. 2014; 5:99-103. PMID: 24891816.
    View in: PubMed
  27. Zhu H, Wang X, Wallack M, Li H, Carreras I, Dedeoglu A, Hur JY, Zheng H, Li H, Fine R, Mwamburi M, Sun X, Kowall N, Stern RA, Qiu WQ. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease. Mol Psychiatry. 2015 Feb; 20(2):252-62. PMID: 24614496.
    View in: PubMed
  28. Baugh CM, Kroshus E, Daneshvar DH, Stern RA. Perceived coach support and concussion symptom-reporting: differences between freshmen and non-freshmen college football players. J Law Med Ethics. 2014; 42(3):314-22. PMID: 25264089.
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  29. Qiu WQ, Au R, Zhu H, Wallack M, Liebson E, Li H, Rosenzweig J, Mwamburi M, Stern RA. Positive association between plasma amylin and cognition in a homebound elderly population. J Alzheimers Dis. 2014; 42(2):555-63. PMID: 24898659.
    View in: PubMed
  30. Rathi Y, Ning L, Michailovich O, Liao H, Gagoski B, Grant PE, Shenton ME, Stern R, Westin CF, Lin A. Maximum entropy estimation of glutamate and glutamine in MR spectroscopic imaging. Med Image Comput Comput Assist Interv. 2014; 17(Pt 2):749-56. PMID: 25485447.
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  31. Mandelblatt JS, Hurria A, McDonald BC, Saykin AJ, Stern RA, VanMeter JW, McGuckin M, Traina T, Denduluri N, Turner S, Howard D, Jacobsen PB, Ahles T. Cognitive effects of cancer and its treatments at the intersection of aging: what do we know; what do we need to know? Semin Oncol. 2013 Dec; 40(6):709-25. PMID: 24331192.
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  32. Mez J, Stern RA, McKee AC. Chronic traumatic encephalopathy: where are we and where are we going? Curr Neurol Neurosci Rep. 2013 Dec; 13(12):407. PMID: 24136455.
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  33. Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC. Clinical presentation of chronic traumatic encephalopathy. Neurology. 2013 Sep 24; 81(13):1122-9. PMID: 23966253.
    View in: PubMed
  34. Seichepine DR, Stamm JM, Daneshvar DH, Riley DO, Baugh CM, Gavett BE, Tripodis Y, Martin B, Chaisson C, McKee AC, Cantu RC, Nowinski CJ, Stern RA. Profile of self-reported problems with executive functioning in college and professional football players. J Neurotrauma. 2013 Jul 15; 30(14):1299-304. PMID: 23421745.
    View in: PubMed

Curriculum Vitae