Andrew Budson, MD

Professor of Neurology, Director, AD & CTE Center Education Core, Associate Director, ADC Research

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Dr. Andrew E. Budson received his B.A. in Chemistry and Philosophy from Haverford College (1988) and his M.D. from Harvard Medical School (1993). He served as an intern in Internal Medicine at Brigham and Women’s Hospital (1993-94).  He was resident and Chief Resident in Neurology at the Harvard-Longwood Program (1994-97). He was a clinical Fellow in Behavioral Neurology at Brigham and Women’s Hospital (1997-99) and a research Fellow in Psychology at Harvard University (1997-2000).  He began as the Clinical Director of the Geriatric Research Education Clinical Center (GRECC) at the Bedford VA Hospital in 2004 and later served as overall Bedford GRECC Director (2008-2010).  After serving a year as Bedford’s Acting Chief of Staff (2009-2010) he moved to the VA Boston Healthcare System as Deputy Chief of Staff in 2010.  In 2012 he became the Associate Chief of Staff for Education. He is Professor of Neurology at Boston University School of Medicine, Associate Director for Research at the Boston University Alzheimer’s Disease Center, Lecturer in Neurology at Harvard Medical School, and Consultant Neurologist at the Division of Cognitive and Behavioral Neurology, Department of Neurology, at Brigham and Women’s Hospital.  Dr. Budson has had continual NIH research funding since 1998, receiving a National Research Service Award and a Career Development Award in addition to a Research Project (R01) grant.  He continues to see patients while teaching fellows, residents, and medical students in his memory disorders clinic at VA Boston.  He is board certified in Neurology.

Dr. Budson’s curriculum vitae

Research Interests

Dr. Budson’s research interests include understanding memory in patients with Alzheimer’s disease and other brain disorders.  His recent work in patients with Alzheimer’s disease has focused on reducing false memories and using strategies, pictures, and music to enhance memory. More about his research can be found in his laboratory, the Center for Translational Cognitive Neuroscience.

ADC Role

Dr. Budson is the Associate Director for Research at the BU ADC and the Director of the Education Core.

Awards/Memberships

Dr. Budson was chosen to give the first Annual Laird Cermak Memorial Lecture, and has been invited to speak around the world, including at the Institute of Cognitive Neuroscience, Queen Square, London.

Recent Publications

For full list of publications click here.

  1. Solomon TM, Leech J, deBros GB, Murphy CA, Budson AE, Vassey EA, Solomon PR. A randomized, double-blind, placebo controlled, parallel group, efficacy study of alpha BRAIN® administered orally. Hum Psychopharmacol. 2016 Mar; 31(2):135-43. PMID: 26876224.
    View in: PubMed
  2. Whiteman AS, Young DE, Budson AE, Stern CE, Schon K. Entorhinal volume, aerobic fitness, and recognition memory in healthy young adults: A voxel-based morphometry study. Neuroimage. 2016 Feb 1; 126:229-38. PMID: 26631814.
    View in: PubMed
  3. Cecchi M, Moore DK, Sadowsky CH, Solomon PR, Doraiswamy PM, Smith CD, Jicha GA, Budson AE, Arnold SE, Fadem KC. A clinical trial to validate event-related potential markers of Alzheimer’s disease in outpatient settings. Alzheimers Dement (Amst). 2015 Dec; 1(4):387-94. PMID: 27239520.
    View in: PubMed
  4. Quiroz YT, Willment KC, Castrillon G, Muniz M, Lopera F, Budson A, Stern CE. Successful Scene Encoding in Presymptomatic Early-Onset Alzheimer’s Disease. J Alzheimers Dis. 2015 Aug 11; 47(4):955-64. PMID: 26401774.
    View in: PubMed
  5. O’Connor MK, Deason RG, Reynolds E, Tat MJ, Flannery S, Solomon PR, Vassey EA, Budson AE. The imagination inflation effect in healthy older adults and patients with mild Alzheimer’s disease. Neuropsychology. 2015 Jul; 29(4):550-60. PMID: 25893972.
    View in: PubMed
  6. Hirst W, Phelps EA, Meksin R, Vaidya CJ, Johnson MK, Mitchell KJ, Buckner RL, Budson AE, Gabrieli JD, Lustig C, Mather M, Ochsner KN, Schacter D, Simons JS, Lyle KB, Cuc AF, Olsson A. A ten-year follow-up of a study of memory for the attack of September 11, 2001: Flashbulb memories and memories for flashbulb events. J Exp Psychol Gen. 2015 Jun; 144(3):604-23. PMID: 25751741.
    View in: PubMed
  7. Rosa NM, Deason RG, Budson AE, Gutchess AH. Self-referencing and false memory in mild cognitive impairment due to Alzheimer’s disease. Neuropsychology. 2015 Sep; 29(5):799-805. PMID: 25689510.
    View in: PubMed
  8. Sun X, Salat D, Upchurch K, Deason R, Kowall N, Budson A. Destruction of white matter integrity in patients with mild cognitive impairment and Alzheimer disease. J Investig Med. 2014 Oct; 62(7):927-33. PMID: 25046178.
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  9. Montenigro PH, Baugh CM, Daneshvar DH, Mez J, Budson AE, Au R, Katz DI, Cantu RC, Stern RA. Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome. Alzheimers Res Ther. 2014; 6(5):68. PMID: 25580160.
    View in: PubMed
  10. Rosa NM, Deason RG, Budson AE, Gutchess AH. Source Memory for Self and Other in Patients With Mild Cognitive Impairment due to Alzheimer’s Disease. J Gerontol B Psychol Sci Soc Sci. 2016 Jan; 71(1):59-65. PMID: 24904049.
    View in: PubMed
  11. Solomon TM, deBros GB, Budson AE, Mirkovic N, Murphy CA, Solomon PR. Correlational analysis of 5 commonly used measures of cognitive functioning and mental status: an update. Am J Alzheimers Dis Other Demen. 2014 Dec; 29(8):718-22. PMID: 24829061.
    View in: PubMed
  12. Waring JD, Seiger AN, Solomon PR, Budson AE, Kensinger EA. Memory for the 2008 presidential election in healthy ageing and mild cognitive impairment. Cogn Emot. 2014; 28(8):1407-21. PMID: 24533684.
    View in: PubMed
  13. Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC. Clinical presentation of chronic traumatic encephalopathy. Neurology. 2013 Sep 24; 81(13):1122-9. PMID: 23966253.
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  14. Qiu WQ, Mwamburi M, Besser LM, Zhu H, Li H, Wallack M, Phillips L, Qiao L, Budson AE, Stern R, Kowall N. Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer’s disease in the absence of apolipoprotein E4 allele. J Alzheimers Dis. 2013; 37(2):421-8. PMID: 23948883.
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  15. McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, Abraham CR, Ikezu T, Reichard RR, Wolozin BL, Budson AE, Goldstein LE, Kowall NW, Cantu RC. The spectrum of disease in chronic traumatic encephalopathy. Brain. 2013 Jan; 136(Pt 1):43-64. PMID: 23208308.
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  16. Budson AE, Solomon PR. New criteria for Alzheimer disease and mild cognitive impairment: implications for the practicing clinician. Neurologist. 2012 Nov; 18(6):356-63. PMID: 23114667.
    View in: PubMed
  17. Simmons-Stern NR, Deason RG, Brandler BJ, Frustace BS, O’Connor MK, Ally BA, Budson AE. Music-based memory enhancement in Alzheimer’s disease: promise and limitations. Neuropsychologia. 2012 Dec; 50(14):3295-303. PMID: 23000133.
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  18. Embree LM, Budson AE, Ally BA. Memorial familiarity remains intact for pictures but not for words in patients with amnestic mild cognitive impairment. Neuropsychologia. 2012 Jul; 50(9):2333-40. PMID: 22705441.
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  19. Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC. Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Sci Transl Med. 2012 May 16; 4(134):134ra60. PMID: 22593173.
    View in: PubMed
  20. Hussey EP, Smolinsky JG, Piryatinsky I, Budson AE, Ally BA. Using mental imagery to improve memory in patients with Alzheimer disease: trouble generating or remembering the mind’s eye? Alzheimer Dis Assoc Disord. 2012 Apr-Jun; 26(2):124-34. PMID: 21946012.
    View in: PubMed
  21. Budson AE, Solomon PR. New diagnostic criteria for Alzheimer’s disease and mild cognitive impairment for the practical neurologist. Pract Neurol. 2012 Apr; 12(2):88-96. PMID: 22450454.
    View in: PubMed
  22. Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10):3985-90. PMID: 22343285.
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  23. Koikkalainen J, Pölönen H, Mattila J, van Gils M, Soininen H, Lötjönen J. Improved classification of Alzheimer’s disease data via removal of nuisance variability. PLoS One. 2012; 7(2):e31112. PMID: 22348041.
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  24. Deason RG, Hussey EP, Budson AE, Ally BA. Gist-based conceptual processing of pictures remains intact in patients with amnestic mild cognitive impairment. Neuropsychology. 2012 Mar; 26(2):202-8. PMID: 22229341.
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  25. Deason RG, Hussey EP, Ally BA, Budson AE. Changes in response bias with different study-test delays: evidence from young adults, older adults, and patients with Alzheimer’s disease. Neuropsychology. 2012 Jan; 26(1):119-26. PMID: 22409339.
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  26. Chu C, Hsu AL, Chou KH, Bandettini P, Lin C. Does feature selection improve classification accuracy? Impact of sample size and feature selection on classification using anatomical magnetic resonance images. Neuroimage. 2012 Mar; 60(1):59-70. PMID: 22166797.
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  27. Quiroz YT, Lopera F, Budson AE. Charting the path for early diagnosis and prevention of Alzheimer’s disease. Expert Rev Neurother. 2011 Dec; 11(12):1665-7. PMID: 22091590.
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  28. Wolz R, Julkunen V, Koikkalainen J, Niskanen E, Zhang DP, Rueckert D, Soininen H, Lötjönen J. Multi-method analysis of MRI images in early diagnostics of Alzheimer’s disease. PLoS One. 2011; 6(10):e25446. PMID: 22022397.
    View in: PubMed
  29. Mattila J, Koikkalainen J, Virkki A, van Gils M, Lötjönen J. Design and application of a generic clinical decision support system for multiscale data. IEEE Trans Biomed Eng. 2012 Jan; 59(1):234-40. PMID: 21990325.
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  30. Rasmussen JM, Lakatos A, van Erp TG, Kruggel F, Keator DB, Fallon JT, Macciardi F, Potkin SG. Empirical derivation of the reference region for computing diagnostic sensitive ¹8fluorodeoxyglucose ratios in Alzheimer’s disease based on the ADNI sample. Biochim Biophys Acta. 2012 Mar; 1822(3):457-66. PMID: 21958592.
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  31. Quiroz YT, Ally BA, Celone K, McKeever J, Ruiz-Rizzo AL, Lopera F, Stern CE, Budson AE. Event-related potential markers of brain changes in preclinical familial Alzheimer disease. Neurology. 2011 Aug 2; 77(5):469-75. PMID: 21775732.
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  32. Werheid K, McDonald RS, Simmons-Stern N, Ally BA, Budson AE. Familiar smiling faces in Alzheimer’s disease: understanding the positivity-related recognition bias. Neuropsychologia. 2011 Aug; 49(10):2935-40. PMID: 21736891.
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  33. Dodson CS, Spaniol M, O’Connor MK, Deason RG, Ally BA, Budson AE. Alzheimer’s disease and memory-monitoring impairment: Alzheimer’s patients show a monitoring deficit that is greater than their accuracy deficit. Neuropsychologia. 2011 Jul; 49(9):2609-18. PMID: 21620877.
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  34. Rosenbloom MH, Brown J, Berlowitz DR, Budson AE. Safety and tolerability of galantamine SA in dementia patients transitioned from donepezil. Consult Pharm. 2011 Feb; 26(2):108-10. PMID: 21310708.
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  35. Quiroz YT, Budson AE, Celone K, Ruiz A, Newmark R, Castrillón G, Lopera F, Stern CE. Hippocampal hyperactivation in presymptomatic familial Alzheimer’s disease. Ann Neurol. 2010 Dec; 68(6):865-75. PMID: 21194156.
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  36. McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, Budson AE. TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2010 Sep; 69(9):918-29. PMID: 20720505.
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  37. Wolk DA, Budson AE. Memory systems. Continuum (Minneap Minn). 2010 Aug; 16(4 Behavioral Neurology):15-28. PMID: 22810510.
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