Rhoda Au, PhD

Professor, Department of Neurology

Dr. RhRhoda_Auoda Au completed her undergraduate degree at Pomona College in California . She earned her PhD from the University of California, Riverside, as well as an MBA from Boston University in 1995. She joined the Boston University School of Medicine’s Department of Neurology in 1986 as a Research Instructor, and she is currently a Professor in the Department of Neurology.

Research Interests

Dr. Au’s research interests are focused on aging and dementia, and include relating cardiovascular risk factors, brain MRI measures, and neuropathology to cognitive performance.  She is also interested in merging research and technology as the path toward innovative science.

ADC Role

At present, Dr. Au is Director of Neuropsychology for the Framingham Heart Study (FHS) and serves to facilitate the collaboration between FHS and the BU ADC.

Memberships

Dr. Au is a member of the International Neuropsychological Society.

Recent Publications

Click here for full list of publications.

  1. Therkelsen KE, Preis SR, Beiser A, DeCarli C, Seshadri S, Wolf P, Au R, Fox CS. Neck Circumference, Brain Imaging Measures, and Neuropsychological Testing Measures. J Stroke Cerebrovasc Dis. 2016 Jul; 25(7):1570-81. PMID: 27056441.
    View in: PubMed
  2. Lebowitz BK, Weinstein C, Beiser A, Seshadri S, Wolf PA, Auerbach S, Au R. Lifelong Reading Disorder and Mild Cognitive Impairment: Implications for Diagnosis. J Alzheimers Dis. 2015 Nov 25; 50(1):41-5. PMID: 26639959.
    View in: PubMed
  3. Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, Wolf PA, Seshadri S, Petersen RC. Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging. Neurology. 2015 Nov 10; 85(19):1712-21. PMID: 26453643.
    View in: PubMed
  4. Ahmed S, Brennan L, Eppig J, Price CC, Lamar M, Delano-Wood L, Bangen KJ, Edmonds EC, Clark L, Nation DA, Jak A, Au R, Swenson R, Bondi MW, Libon DJ. Visuoconstructional Impairment in Subtypes of Mild Cognitive Impairment. Appl Neuropsychol Adult. 2016 Jan-Feb; 23(1):43-52. PMID: 26397732.
    View in: PubMed
  5. Qiu WQ, Zhu H, Dean M, Liu Z, Vu L, Fan G, Li H, Mwamburi M, Steffens DC, Au R. Amyloid-associated depression and ApoE4 allele: longitudinal follow-up for the development of Alzheimer’s disease. Int J Geriatr Psychiatry. 2016 Mar; 31(3):316-22. PMID: 26250797.
    View in: PubMed
  6. Nishtala A, Himali JJ, Beiser A, Murabito JM, Seshadri S, Wolf PA, Au R. Midlife Hypertension Risk and Cognition in the Non-Demented Oldest Old: Framingham Heart Study. J Alzheimers Dis. 2015 Jul 9; 47(1):197-204. PMID: 26402768.
    View in: PubMed
  7. Weinstein G, Maillard P, Himali JJ, Beiser AS, Au R, Wolf PA, Seshadri S, DeCarli C. Glucose indices are associated with cognitive and structural brain measures in young adults. Neurology. 2015 Jun 9; 84(23):2329-37. PMID: 25948725.
    View in: PubMed
  8. Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke. 2015 May; 46(5):1161-6. PMID: 25908455.
    View in: PubMed
  9. Gupta A, Preis SR, Beiser A, Devine S, Hankee L, Seshadri S, Wolf PA, Au R. Mid-life Cardiovascular Risk Impacts Memory Function: The Framingham Offspring Study. Alzheimer Dis Assoc Disord. 2015 Apr-Jun; 29(2):117-23. PMID: 25187219.
    View in: PubMed
  10. Libon DJ, Preis SR, Beiser AS, Devine S, Seshadri S, Wolf PA, DeCarli C, Au R. Verbal memory and brain aging: an exploratory analysis of the role of error responses in the Framingham Study. Am J Alzheimers Dis Other Demen. 2015 Sep; 30(6):622-8. PMID: 25788434.
    View in: PubMed
  11. Jefferson AL, Beiser AS, Himali JJ, Seshadri S, O’Donnell CJ, Manning WJ, Wolf PA, Au R, Benjamin EJ. Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study. Circulation. 2015 Apr 14; 131(15):1333-9. PMID: 25700178.
    View in: PubMed
  12. Miller IN, Himali JJ, Beiser AS, Murabito JM, Seshadri S, Wolf PA, Au R. Normative Data for the Cognitively Intact Oldest-Old: The Framingham Heart Study. Exp Aging Res. 2015; 41(4):386-409. PMID: 26214098.
    View in: PubMed
  13. Jefferson AL, Beiser AS, Seshadri S, Wolf PA, Au R. APOE and mild cognitive impairment: the Framingham Heart Study. Age Ageing. 2015 Mar; 44(2):307-11. PMID: 25497326.
    View in: PubMed
  14. Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SL, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, Eiriksdottir G, Assareh AA, Kochan NA, Widen E, Palotie A, Hsieh YC, Eriksson JG, Vogler C, van Swieten JC, Shulman JM, Beiser A, Rotter J, Schmidt CO, Hoffmann W, Nöthen MM, Ferrucci L, Attia J, Uitterlinden AG, Amouyel P, Dartigues JF, Amieva H, Räikkönen K, Garcia M, Wolf PA, Hofman A, Longstreth WT, Psaty BM, Boerwinkle E, DeJager PL, Sachdev PS, Schmidt R, Breteler MM, Teumer A, Lopez OL, Cichon S, Chasman DI, Grodstein F, Müller-Myhsok B, Tzourio C, Papassotiropoulos A, Bennett DA, Ikram MA, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63. PMID: 25648963.
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  15. Yun CH, Kim H, Lee SK, Suh S, Lee SH, Park SH, Thomas RJ, Au R, Shin C. Daytime sleepiness associated with poor sustained attention in middle and late adulthood. Sleep Med. 2015 Jan; 16(1):143-51. PMID: 25534582.
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  16. 2014 Report on the Milestones for the US National Plan to Address Alzheimer’s Disease. Alzheimers Dement. 2014 Oct; 10(5 Suppl):S430-52. PMID: 25341459.
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  17. Montenigro PH, Baugh CM, Daneshvar DH, Mez J, Budson AE, Au R, Katz DI, Cantu RC, Stern RA. Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome. Alzheimers Res Ther. 2014; 6(5):68. PMID: 25580160.
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  18. Chouraki V, Beiser A, Younkin L, Preis SR, Weinstein G, Hansson O, Skoog I, Lambert JC, Au R, Launer L, Wolf PA, Younkin S, Seshadri S. Plasma amyloid-ß and risk of Alzheimer’s disease in the Framingham Heart Study. Alzheimers Dement. 2015 Mar; 11(3):249-57.e1. PMID: 25217292.
    View in: PubMed
  19. Kaur B, Himali JJ, Seshadri S, Beiser AS, Au R, McKee AC, Auerbach S, Wolf PA, DeCarli CS. Association between neuropathology and brain volume in the Framingham Heart Study. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):219-25. PMID: 24614264.
    View in: PubMed
  20. Edmonds EC, Delano-Wood L, Clark LR, Jak AJ, Nation DA, McDonald CR, Libon DJ, Au R, Galasko D, Salmon DP, Bondi MW. Susceptibility of the conventional criteria for mild cognitive impairment to false-positive diagnostic errors. Alzheimers Dement. 2015 Apr; 11(4):415-24. PMID: 24857234.
    View in: PubMed
  21. Weinstein G, Preis SR, Beiser AS, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Seshadri S. Cognitive performance after stroke–the Framingham Heart Study. Int J Stroke. 2014 Oct; 9 Suppl A100:48-54. PMID: 25352473.
    View in: PubMed
  22. Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, Roubenoff R, Pikula A, Au R, Braverman LE, Wolf PA, Vasan RS, Seshadri S. Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy. Neurology. 2014 May 6; 82(18):1613-9. PMID: 24706014.
    View in: PubMed
  23. Chêne G, Beiser A, Au R, Preis SR, Wolf PA, Dufouil C, Seshadri S. Gender and incidence of dementia in the Framingham Heart Study from mid-adult life. Alzheimers Dement. 2015 Mar; 11(3):310-20. PMID: 24418058.
    View in: PubMed
  24. Qiu WQ, Au R, Zhu H, Wallack M, Liebson E, Li H, Rosenzweig J, Mwamburi M, Stern RA. Positive association between plasma amylin and cognition in a homebound elderly population. J Alzheimers Dis. 2014; 42(2):555-63. PMID: 24898659.
    View in: PubMed
  25. Libon DJ, Drabick DA, Giovannetti T, Price CC, Bondi MW, Eppig J, Devlin K, Nieves C, Lamar M, Delano-Wood L, Nation DA, Brennan L, Au R, Swenson R. Neuropsychological syndromes associated with Alzheimer’s/vascular dementia: a latent class analysis. J Alzheimers Dis. 2014; 42(3):999-1014. PMID: 25024329.
    View in: PubMed
  26. Bondi MW, Edmonds EC, Jak AJ, Clark LR, Delano-Wood L, McDonald CR, Nation DA, Libon DJ, Au R, Galasko D, Salmon DP. Neuropsychological criteria for mild cognitive impairment improves diagnostic precision, biomarker associations, and progression rates. J Alzheimers Dis. 2014; 42(1):275-89. PMID: 24844687.
    View in: PubMed
  27. Weinstein G, Beiser AS, Choi SH, Preis SR, Chen TC, Vorgas D, Au R, Pikula A, Wolf PA, DeStefano AL, Vasan RS, Seshadri S. Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. JAMA Neurol. 2014 Jan; 71(1):55-61. PMID: 24276217.
    View in: PubMed
  28. Nishtala A, Preis SR, Beiser A, Devine S, Hankee L, Seshadri S, Wolf PA, Au R. Midlife cardiovascular risk impacts executive function: Framingham offspring study. Alzheimer Dis Assoc Disord. 2014 Jan-Mar; 28(1):16-22. PMID: 23995818.
    View in: PubMed
  29. Vu LN, Dean MJ, Mwamburi M, Au R, Qiu WQ. Executive function and mortality in homebound elderly adults. J Am Geriatr Soc. 2013 Dec; 61(12):2128-34. PMID: 24479144.
    View in: PubMed
  30. Murabito JM, Beiser AS, Decarli C, Seshadri S, Wolf PA, Au R. Parental longevity is associated with cognition and brain ageing in middle-aged offspring. Age Ageing. 2014 May; 43(3):358-63. PMID: 24212919.
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  31. Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Rockwood K, Xiao S, Li J, Li X, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Carrière I, Ancelin ML, Seshadri S, Au R, Beiser AS, Lam LC, Wong CH, Fung AW, Kim KW, Han JW, Kim TH, Petersen RC, Roberts RO, Mielke MM, Ganguli M, Dodge HH, Hughes T, Anstey KJ, Cherbuin N, Butterworth P, Ng TP, Gao Q, Reppermund S, Brodaty H, Meguro K, Schupf N, Manly J, Stern Y, Lobo A, Lopez-Anton R, Santabárbara J. COSMIC (Cohort Studies of Memory in an International Consortium): an international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups. BMC Neurol. 2013; 13:165. PMID: 24195705.
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  32. Ahl RE, Beiser A, Seshadri S, Auerbach S, Wolf PA, Au R. Defining MCI in the Framingham Heart Study Offspring: education versus WRAT-based norms. Alzheimer Dis Assoc Disord. 2013 Oct-Dec; 27(4):330-6. PMID: 23314066.
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