BU ADC Happenings
The Boston University Alzheimer’s Disease Center (BU ADC) welcomes new staff members: Nicole Cantwell, research assistant to Dr. Angela Jefferson and PAIRS Program Coordinator; Patrick Curtis, administrative assistant to Drs. Robert Green and Robert Stern; Fareesa Islam, administrative assistant to Dr. Angela Jefferson; Patricia Johnson, psychometrician on the ELAN and ADAPT studies; Denise Lautenbach, MS, Genetic Counselor and REVEAL Project Manager; Theresa McGowan, psychometrician on the ELAN study; and Silvia Serrano, MPH, BU ADC Outreach & Recruitment Coordinator. We also extend a warm welcome to our new student trainees: Michael Dombek, a senior at Boston University, and Bhaavika Patel, a junior at Boston University, who are both working with Dr. Jefferson; and Brittany Masatsugu, a Boston University graduate student who is working as a HOPE psychometrician.
Dr. Alpaslan Dedeoglu, Director of the Translational Neurotherapeutics Laboratory and BU ADC Translational Core Associate Director, recently received an R01 grant from the National Institute on Aging. Dr. Dedeoglu’s project, “Cyclohexanehexol Therapy in Transgenic Models of Alzheimer’s disease (AD),” assesses transgenic mouse brains and the correlation between amyloid-beta and neurofibrillary tangles with magnetic resonance imaging, magnetic resonance spectroscopy, and cognitive function. Dr. Dedeoglu is also investigating the effect of non-steroidal antiinflammatory drugs and inositols that may alter amyloid-beta aggregation. The BU ADC would like to congratulate Dr. Gwendalyn King, a biochemistry postdoctoral fellow with Dr. Carmela Abraham, who was awarded a prestigious K99 award from the National Institute on Aging for research on the anti-aging/protective gene Klotho. Dr. Abraham’s group found that Klotho levels are decreased in the aged brain and more so in models of AD. Dr. King’s award will allow her to continue studies to determine why Klotho is decreased with age and how its production is regulated in the brain. In parallel studies, Dr. King has identified potential novel drugs to elevate the Klotho protein. Experiments in animals will establish whether increasing this molecule is protective against neurodegenerative diseases, such as AD.
Many thanks and best wishes to the BU ADC staff who have recently left to pursue new directions: Susan Hiraki, MS, who left the REVEAL Study in May to pursue a master’s degree in public health in New York; and Stephanie Sikora, who left the BU ADC in September to relocate to Arizona. Thank you and best wishes to our recent student trainees: Monique Pimontel, who completed her master’s degree at Boston University and has since moved to New York to pursue a psychometrician position; and Morgan McGillicuddy, who has left to pursue her PhD in clinical psychology at the University of Maine.
Greater Boston Memory Walk
The Memory Walk is the Alzheimer’s Association’s largest fundraising event. Walks take place annually in more than 600 communities nationwide. On Sunday, September 27th, the faculty, staff, participants and friends of the Boston University Alzheimer’s Disease Center (BU ADC) participated in the Greater Boston Memory Walk in Cambridge, MA. This year, the BU ADC team welcomed staff and friends of one of our continuing care retirement community affiliates, Senior Living Residences, and together we raised over $11,000 for the Alzheimer’s Association!