This advanced-level course builds on the content of EH705. The course uses a case study approach to teach the molecular mechanisms by which compounds exert their toxicity in addition to dose-response analyses that are applicable to regulatory toxicology. Experimental methods and toxicological data that are generated are presented and discussed for each of the case studies. The most recent literature is consulted to support the most up-to-date analyses of toxic mechanisms. Major topics include cellular mechanisms of action of toxicants as they relate to endocrine/reproductive toxicology, neurotoxicology, and immunotoxicology, and the use of these data in regulatory toxicology. Up and coming areas (e.g. microbiome) and contentious chemicals (e.g. glyphosate and PFAS) are included each year.

Note that this information may change at any time. Please visit the Student Link for the most up-to-date course information.