The course descriptions below are correct to the best of our knowledge as of May 2014. Instructors reserve the right to update and/or otherwise alter course descriptions as necessary after publication. The listing of a course description here does not guarantee a course’s being offered in a particular semester. The Course Rotation Guide lists the expected semester a course will be taught. Please refer to the published schedule of classes for confirmation a class is actually being taught and for specific course meeting dates and times. In addition to the courses listed in the bulletin and courses approved after June 1, 2014, SPH, SPH degree candidates may register for a directed (independent) study with a full-time SPH faculty member. For more information, speak with your faculty advisor or a staff member in the SPH Registrar’s Office.

Analysis of Correlated Data

SPH BS 857 (4 credits)

The purpose of this advanced seminar is to present some of the modern methods for analyzing tricorrelated observations. Such data may arise in longitudinal studies where repeated observations are collected on study subjects or in studies in which there is a natural clustering of observations, such as a multi-center study of observations clustered within families. Students start with a review of methods for repeated measures analysis of variance and proceed to more complicated study designs. The course presents both likelihood-based methods and quasi-likelihood methods. Marginal, random effects and transition models are discussed. Students apply these methods in homework assignments and a project.

2015SPRGSPHBS857 A1, Jan 15th to May 7th 2015
Days Start End Type Bldg Room
R 2:00 pm 4:45 pm

Statistical Genetics I

SPH BS 858 (4 credits)

This course covers a variety of statistical applications to human genetic data, including collection and data management of genetic and family history information, and statistical techniques used to identify genes contributing to disease and quantitative traits in humans. Specific topics include basic population genetics, linkage analysis and genetic association analyses with related and unrelated individuals.

2014FALLSPHBS858 A1, Sep 4th to Dec 18th 2014
Days Start End Type Bldg Room
R 2:00 pm 4:45 pm CT 460A

Applied Genetic Analysis

SPH BS 859 (4 credits)

Statistical tools such as linkage and association analysis are used to unravel the genetic component of complex disease. Investigators interested in the genetic analysis of complex traits need a basic understanding of the strengths and weaknesses of these methodologies. This course will provide the student with practical, applied experience in performing linkage and association analyses, including genome-wide analyses. Special emphasis is placed on understanding assumptions and issues related to statistical methodologies for genetic analysis to identify genes influencing complex traits. Students will use specialized genetics software for homework assignments.

2015SPRGSPHBS859 A1, Jan 20th to Apr 30th 2015
Days Start End Type Bldg Room

Statistical Genetics II

SPH BS 860 (4 credits)

This course covers current topics in statistical genetics, with emphasis on how statistical techniques can be used with various types of genetics data for mapping genes responsible/contributing to complex human diseases. Topics such as genetics map functions, gene mapping in experimental organisms, advanced linkage analysis methods, statistical approaches for the analysis of genome-wide high density SNP scans in unrelated and family samples will be discussed.

Applied Statistics in Clinical Trials II

SPH BS 861 (4 credits)

This course covers a variety of biostatistical topics in clinical trials, including presentation of statistical results to regulatory agencies for product approval, analysis of safety data, intent-to-treat analyses and handling of missing data, interim analyses and adaptive designs, and analyses of multiple endpoints. Upon completion of the course, students will be able to make and defend decisions for many study designs and for issues faced when analyzing efficacy and safety data from clinical trials. Students will also be able to present, in a written format following standard guidelines accepted by the clinical trials' community, results of such efficacy and safety analyses to the medical reviewers and statistical reviewers of regulatory agencies.

2014FALLSPHBS861 A1, Sep 3rd to Dec 17th 2014
Days Start End Type Bldg Room
W 6:00 pm 8:45 pm L 201

Continuing Study in Biostatistics

SPH BS 980 (0 credits)

Doctoral students in Biostatistics register each summer and fall for Continuing Study in Biostatistics until they have graduated from their doctoral program. Students will participate in a dissertation workshop and other activities while they are preparing their dissertation. Students are charged for 2 credits equivalent of tuition, for student medical insurance, and all relevant fees. They are certified full time. Students must be registered for this course at GRS.

2014FALLSPHBS980 A1, Sep 2nd to Dec 19th 2014
Days Start End Type Bldg Room
2015SPRGSPHBS980 A1, Jan 8th to May 5th 2015
Days Start End Type Bldg Room

Physiologic Principles for Public Health

SPH EH 710 (4 credits)

This course provides students with a detailed working knowledge of the normal mechanisms of human body function. Physiological mechanisms are studied from the molecular level to the level of organ systems, and emphasis is placed on understanding how body processes are regulated and integrated so as to achieve homeostasis characteristic of a ?normal? healthy individual. Students will become acquainted with both the gross and histological anatomy of major organs. For each system covered, a case study of a disease of significant public health interest is used to reinforce basic physiological principles, and to acquaint students with physiological measurements commonly used in clinical settings. This course is recommended for all students who need a substantive understanding of human physiology for subsequent coursework. This course will be of special value to students whom expect their career?s to involve close interaction with health care providers.

2014FALLSPHEH710 A1, Sep 3rd to Dec 17th 2014
Days Start End Type Bldg Room
MW 10:00 am 11:45 am L 213

Molecular Biology and Public Health

SPH EH 713 (4 credits)

The last 10 years has seen an explosion in the discipline of molecular biology that has important implications for our current and future approach to public health. Therefore, an understanding of the principal concepts of this field is critical to the modern public health practitioner. The goal of this course is to equip students with the ability to understand the potential applications of genetic engineering to their health specialties. In particular, the course introduces the student to the basic concepts of cellular biology and molecular genetics and investigates the use of a number of powerful molecular techniques including, but not limited to, gene cloning, genetic engineering of animals and plants, identification of molecular bio-markers of susceptibility, and mining of the human genome database. The implications of these advances vis-a-vis right to privacy, discrimination, and other ethical issues are also addressed. While a background in biology is helpful, this course is negotiable by any student showing a high level of enthusiasm for scientific discovery.

2015SPRGSPHEH713 A1, Jan 13th to Apr 28th 2015
Days Start End Type Bldg Room
T 2:00 pm 4:45 pm

Foundations of Environmental Health

SPH EH 717 (3 credits)

EH717 is the introductory core course that focuses on assessment and control of a broad range of physical, chemical, and biological factors in the natural and built environment that affect the health of individuals and populations. EH717 addresses an array of environmental issues including emergency preparedness; food safety and regulation; electromagnetic radiation; energy utilization; solid, liquid, and hazardous materials management; the fate of chemicals in the environment; vector control; livestock production; air and water quality; occupational health and safety; the built environment; environmental justice; and other timely environmental issues of growing importance across the globe.

2014FALLSPHEH717 A1, Sep 8th to Dec 15th 2014
Days Start End Type Bldg Room
M 2:00 pm 4:30 pm L 112
2014FALLSPHEH717 B1, Sep 2nd to Dec 16th 2014
Days Start End Type Bldg Room
T 6:00 pm 8:30 pm L 110
2014FALLSPHEH717 C1, Sep 3rd to Dec 17th 2014
Days Start End Type Bldg Room
W 2:00 pm 4:30 pm L 112
2014FALLSPHEH717 D1, Sep 5th to Dec 19th 2014
Days Start End Type Bldg Room
F 10:00 am 12:30 pm 670 107/8
2015SPRGSPHEH717 A1, Jan 13th to May 5th 2015
Days Start End Type Bldg Room
T 10:00 am 12:30 pm
2015SPRGSPHEH717 B1, Jan 13th to May 5th 2015
Days Start End Type Bldg Room
T 6:00 pm 8:30 pm
2015SPRGSPHEH717 C1, Jan 16th to May 1st 2015
Days Start End Type Bldg Room
F 10:00 am 12:30 pm

Analytical Methods in Environmental Health

SPH EH 725 (2 credits)

Students in this course learn the skills, methods and critical thinking framework necessary for upper level environmental health courses and for success as public health professionals. Environmental Health is a field of public health in which environmental hazards and health risks to populations are identified, assessed and managed through a data-driven process. This course extends the depth of concepts taught in EH717 and should be taken concurrently for students entering in the fall semester. We take the opportunity to partner with communities to design and conduct a data collection and analysis effort that is suitable for rigorous analyses with the many tools commonly used in environmental health.

2014FALLSPHEH725 A1, Sep 8th to Dec 15th 2014
Days Start End Type Bldg Room
M 6:00 pm 7:30 pm L 203

The Environmental Determinants of Infectious Diseases

SPH EH 735 (2 credits)

The environment is a key determinant of infectious disease burden in a population. This course presents an overview of how existing and, in particular, changing global environmental factors can affect the transmission cycle of infectious pathogens in both developing and industrialized countries. It examines issues of water, sanitation and hygiene in resource-limited settings that contribute enormously to childhood death due to infectious diarrheal diseases, and to morbidity and mortality due to neglected tropical diseases (NTDs). It also explores how environmental alterations and natural disasters can result in ecological changes that impact on the maintenance and spread of infectious diseases in a community. Sustainable environmental intervention strategies to reduce the burden of infectious diseases will be considered for each of the major diseases covered in class. This course is appropriate for MPH students and undergraduates, especially those interested in biology, global health, and the environment.

2015SPRGSPHEH735 A1, Jan 14th to May 6th 2015
Days Start End Type Bldg Room
W 2:00 pm 4:00 pm

Wastewater and Health/Sustainable Sanitation

SPH EH 745 (2 credits)

This course provides students with an overview of the relationship between human health, ecological health, and sanitation. The different disposal and treatment methods for human excreta are described in their historical and political contexts. Related topics such as the land appliation of sewage sludge, the role of government agencies, nongovernmental organizations, and public health experts are presented as well as practical solutions toward sustainable sanitation. This course involves a group project and a paper.

2014FALLSPHEH745 A1, Oct 29th to Dec 17th 2014
Days Start End Type Bldg Room
W 10:00 am 1:00 pm L 211

Global Environmental Health

SPH EH 749 (4 credits)

Environmental issues and related health outcomes vary between developing and developed countries and among geographical regions and countries; however, just as economies have become interrelated globally so have environmental problems. This class introduces students to 1) frameworks for understanding global environmental health issues including sustainable development and the demographic/epidemiological/environmental transitions; 2)methods for characterizing global environmental burdens of disease, including linkages with surveillance systems and information gaps among countries; and 3) the role of international institutions and organizations. The course will use a series of examples and cases to illustrate the complexities of global environmental problems.

2015SPRGSPHEH749 A1, Jan 20th to Apr 30th 2015
Days Start End Type Bldg Room

Water Quality and Public Health

SPH EH 750 (2 credits)

This course is a lecture and methods course on water resources and public health. Water supply and water quality discussions provide an overview of the technical and scientific basis on which public health decisions are made regarding disease prevention and community health. The chemical, physical, and biological processes necessary for designing and managing municipal drinking water treatment plants are analyzed. Water quality topics include standards and regulations; non-point source runoff;point source discharge; and water quality analysis of drinking and surface waters. Students will sample, analyze and use water quality objectives for comparison. Social, political, and economic factors effecting water quality and treatment will be discussed. The course will conclude with historical and international perspectives on water resources and management.

2014FALLSPHEH750 A1, Sep 3rd to Oct 22nd 2014
Days Start End Type Bldg Room
W 10:00 am 12:30 pm L 109AB

Environmental Epidemiology

SPH EH 757 (4 credits)

This course introduces students to epidemiologic investigations of environmental health problems. Topics include both traditional and innovative subjects and strategies, such as the health effects associated with air and water contaminants, toxic waste sites, lead, and radiation, as well as environmental exposures that have received attention only recently, such as endocrine disruptors and electromagnetic fields. The course emphasizes epidemiologic methods, particularly exposure assessment, modeling, cluster analysis, and sources of bias. Students gain experience in the critical review and design of related epidemiologic studies. This course counts as concentration credit for epidemiology concentrators.

2014FALLSPHEH757 A1, Sep 8th to Dec 15th 2014
Days Start End Type Bldg Room
M 2:00 pm 4:45 pm L 213

Introduction to Toxicology

SPH EH 768 (4 credits)

This introductory course presents the basic concepts of toxicology, including dose-response relationships, biological and chemical factors that influence toxicity, types of harmful effects, principles of testing for toxic effects and the underlying concepts behind toxicant-induced disease susceptibility. Toxicants found in the environment, such as metals, pesticides and industrial pollutants, are studied. The course assumes basic knowledge of chemistry and biology, although there are no prerequisites. This course is required of all Environmental Health concentrators.

2015SPRGSPHEH768 A1, Jan 13th to Apr 28th 2015
Days Start End Type Bldg Room
T 6:00 pm 8:45 pm

Great Calamities and Their Consequences for Public Health

SPH EH 780 (4 credits)

Current public health practice in the United States evolved in response to public health calamities. Epidemics of infectious disease, mass poisonings, and industrial disasters have served as catalysts for new regulations and institutions of public health. For example, the sulfanilamide tragedy of 1937 was the catalyst for the current drug approval process. In addition, public and private responses to calamities have fueled the development of scientific knowledge and epidemiologi methods. For example, John Snow's investigation of the London cholera outbreak of 1854 demonstrated the utility of observational epidemiology. This course acquaints students with those calamities of primarily the past 200 years that were most consequential for public health practice. The emphasis is on each calamity's impact on knowledge of disease causation and control and on the development of public health institutions and regulations.

Community-Based Methods in Environmental Health

SPH EH 800 (4 credits)

Low-income urban communities are exposed to many environmental and non-environmental stressors, but many tools and techniques for public policy decision-making do not adequately address these complex settings. This course focuses on methods for assessing and addressing local community health impacts from environmental stressors, with an emphasis on health impact assessment, community-based participatory research, and analytical methods to evaluate environmental justice. Case examples will include traffic and housing, and students will work with a community group to implement a health impact assessment on a topic of mutual interest.

2015SPRGSPHEH800 A1, Jan 14th to May 6th 2015
Days Start End Type Bldg Room
W 2:00 pm 4:45 pm

Exposure Assessment

SPH EH 804 (4 credits)

The process of assessing exposure is a critical component of occupational and environmental epidemiology, of determining compliance with health and safety regulations, and in conducting human health risk assessments. This course in exposure assessment covers the basic concepts and methods of study design, data collection, and data analysis/interpretation. Students analyze relevant case studies and conduct a study in which they develop their own exposure assessment strategy, collect and analyze data, prepare a final report, and present their findings.

2015SPRGSPHEH804 A1, Jan 12th to May 4th 2015
Days Start End Type Bldg Room
M 2:00 pm 4:45 pm

Environmental Health Science, Policy and Law

SPH EH 805 (4 credits)

This course uses a case-study approach to discuss current and historic controversies in environmental and occupational health policy making. Our specific focus is on the examination of how scientific information (e.g., risk assessments, exposure analyses, epidemiologic studies, clinical case reports,) is used (or is not used) in policy decisions. Students will learn how environmental health laws and regulations are made and challenged, and gain experience looking up laws, regulations and court decisions. Case studies feature international treaties, federal and state court cases, laws, regulations, and policies. Topic areas include air and water quality, hazardous waste, environmental justice, worker safety, and the precautionary principle.