Molecular Genetics

GMS BT 407

Prereq: BT 110 (Intro Biomed Lab Sci), BT 413 (Mol Bio), BT 436 (Genetics) or consent of program director. Advanced course designed for those considering a clinical or research career in human genetics. Emphasis is on clinical molecular genetics (DNA testing). The course covers types of genetic abnormalities, methodology, nomenclature and clinical significance in pregnancy, birth defects, and cancer. Laboratory work includes basic blood extraction, DNA preparation, gel electrophoresis, capillary electrophoresis, sequencing, and identification. The course also provides an updated review of latest molecular genetic methodology and applications, such as copy number analysis, chip based sequencing and next generation sequencing. Laboratory course.

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