Molecules to Molecular Therapeutics
GMS MM 710
This course is designed to provide instruction in all aspects of the translation of basic research observations into clinical applications, using several case study models. The first case study will focus on stem cells/regenerative medicine, where the fundamentals of cell reprogramming is discussed, followed by discussions on how this technology can be used for diagnostics, toxicity screening or directly for in vivo therapeutics. The second study relates to cystic fibrosis. The molecular basis of the disease is reviewed, which leads into the rationale for drug discovery and clinical trials. A similar approach is used for the third case study which is Alzheimer's disease. The course will address treatment strategies for these diseases, including pharmacologic manipulation of gene expression, structural biology and rational drug design, and gene therapy. Additional topics related to clinical trials development will be covered including ethical issues, regulatory affairs, statistical considerations in clinical research, and outcome analysis. Required of all Molecular and Translational Medicine graduate students. 4 cr, Spring sem.
SPRG 2016 Schedule
|A1||TBA||MW 10:00 am-11:50 am||MED Campus|