GMS BT 460
Prereq: One semester of biology, two semesters of chemistry and BT 405 (Biochem). This course covers laboratory technologies utilized in the pre-clinical drug development phase with emphasis on the issues and challenges of molecular targeted therapeutics, a new paradigm in drug discovery. In addition, DNA, RNA and protein-based therapeutics, and gene and stem cell therapies are discussed. Students learn about translational technologies used to identify and validate drug targets, as well as lead optimization and selection of drug candidates. A hands-on laboratory component reinforces drug discovery concepts.