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  • CAS BI 551: Biology of Stem Cells
    Undergraduate Prerequisites: CAS BI 203 or CAS BI 206; , or consent of instructor.
    Views on stem cell research range from assumptions of a potential cure for most diseases to fears that it will depreciate the value of human life. This course equips students with the science that underlies this discussion, including the biological properties of stem cells and the experimental hurdles to utilization in regenerative medicine.
  • CAS BI 552: Molecular Biology 1
    Undergraduate Prerequisites: (CASBI203 or CASBI213) and (CASBI206 or CASBI216).
    Synthesis, structure, and function of biologically important macromolecules (DNA, RNA, and proteins). Regulation and control of the synthesis of RNA and proteins. Introduction to molecular biology of eukaryotes. Discussion of molecular biological techniques, including genetics and recombinant DNA techniques. Three hours lecture, one hour discussion.
  • CAS BI 553: Molecular Biology 2
    Undergraduate Prerequisites: CAS BI 552; (CAS BI/CH 421/422 recommended.)
    This course focuses on eukaryotic gene regulation. Course topics include genome organization and DNA rearrangement, RNA interference and noncoding RNAs, gene editing, mouse transgenic approaches, signal transduction pathways, chromatin structure, and cell cycle. Research articles will be discussed.
  • CAS BI 560: Systems Biology
    Undergraduate Prerequisites: CAS BI 552; or consent of the instructor.
    Examines critical components of systems biology, including design principles of biological systems (e.g., feedback, synergy, cooperativity), and the generation and analysis of large-scale datasets (e.g., protein- protein interaction, mRNA expression).
  • CAS BI 563: Sensory Biology of Aquatic Animals
    Undergraduate Prerequisites: CAS BI 260; and junior or senior standing, or consent of instructor and enrollment in the Marine Semester.
    Underwater signals, physics of signal transmission, receptors, sense organs, animal behavior. Focus on student-generated research projects: design, animal care, data collection, analysis and presentation.
  • CAS BI 565: Functional Genomics
    Undergraduate Prerequisites: CAS BI 552; or consent of instructor.
    This paper- and problem-based course focuses on functional genomics topics such as genetic variation, genome organization, and mechanisms of transcriptional and post-transcriptional gene regulation. Up-to-date methods include NGS, genome editing, ChIP-seq, chromatin accessibility assays, transcriptomics, and proteomics.
  • CAS BI 569: Tropical Marine Invertebrates
    Undergraduate Prerequisites: CAS BI 107 and CAS BI 260; and enrollment in the Marine Semester.
    Explores the diversity of marine invertebrates, including body plans, feeding biology, reproductive strategies, and developmental programs. Field biodiversity surveys and behavioral studies in shallow water tropical marine environments, especially seagrass beds and mangrove.
  • CAS BI 572: Advanced Genetics
    Undergraduate Prerequisites: CAS BI 206 and CAS BI 203; CAS BI 552 is recommended.
    An in-depth study of eukaryotic genetics, ranging from the history and basic principles to current topics and modern experimental approaches. Genetics of Drosophila, C. elegans, mice, and humans are explored in detail, including readings from primary literature. Three hours lecture, one hour discussion.
  • CAS BI 576: Carcinogenesis
    Undergraduate Prerequisites: CAS BI 203 ; CAS BI 206 ; CAS BI 552.
    Covers multiple aspects of cancer biology with a focus on molecular mechanisms underlying cancer development and progression, and the implications for therapy. Topics include oncogenes, tumor suppressors, apoptosis, angiogenesis, metastasis, mouse models, and chemotherapy. Emphasis on current research. Students may not receive credit for more than one of the following courses: CAS BI 327, CAS BI 576, and GMS BT 520.
  • CAS BI 577: Quantitative Approaches in Molecular Biology
    Undergraduate Prerequisites: CAS BI 203 and CAS MA 115 or CAS MA 213.
    Introduces biology graduate students and upper division undergraduate students to concepts and bioinformatics tools necessary for quantitative analysis of biological problems. Students learn the programming language Python, analyze next generation sequencing and transcriptomic data.
  • CAS BI 578: Marine Geographic Information Science
    Undergraduate Prerequisites: CAS BI 260 and CAS ES 144; CASMA213 strongly recommended. Enrollment in the Marine semester required.
    Introduction to marine geographic information systems and spatial analysis for conservation, management, and marine landscape ecology. Comparative examples from Gulf of Maine and tropics. Solve problems in coastal zoning and marine park design, whale and coral reef conservation. Also offered as CAS GE 578.
  • CAS BI 579: Progress in Ecology, Behavior, Evolution, and Marine Biology 1
    Undergraduate Prerequisites: graduate standing in EBE or MB.
    Facilitates presentation and discussion of research ideas, preliminary data, and research progress by all graduate students in Ecology, Behavior, Evolution, and Marine Biology (EBE-MB). All EBE-MB graduate students are encouraged to participate every semester, but receive two credits toward the degree only once, for CAS BI 579 or for CAS BI 580.
  • CAS BI 580: Progress in Ecology, Behavior, Evolution, and Marine Biology 2
    Undergraduate Prerequisites: graduate standing in EBE or MB.
    Facilitates presentation and discussion of research ideas, preliminary data, and research progress by all graduate students in Ecology, Behavior, Evolution, and Marine Biology (EBE-MB). All EBE-MB graduate students are encouraged to participate every semester, but receive two credits toward the degree only once, for CAS BI 579 or for CAS BI 580.
  • CAS BI 581: Seminar in Biology
    Undergraduate Prerequisites: consent of instructor.
    Graduate Prerequisites: consent of instructor.
    Informal discussion and student reports on subjects of current interest based on an intensive study of the literature. Topics vary. Two topics are offered Fall 2018. Section B1: Grant Writing. Seminar course in preparing a research grant proposal. Section H1: Neurobiology of Brain Disorders. Review recent topics and readings in the field of neurodegeneration.
  • CAS BI 582: Seminar in Biology
    Undergraduate Prerequisites: consent of instructor.
    Graduate Prerequisites: consent of instructor.
    Informal discussion and student reports on subjects of current interest based on an intensive study of the literature. Topics and prerequisites vary. Topic for Spring 2018: Sex, Sexes, and Sexual Phenotypes. Discuss topics in the integrative and comparative biology of sex and sexes. Pre-requisite: consent of instructor and graduate or senior standing. Some background in evolution, development and/or behavior recommended.
  • CAS BI 583: Seminar: Progress in Cell and Molecular Biology
    Undergraduate Prerequisites: Open to graduate students only.
    Facilitates presentation and discussion of research ideas, preliminary data, and research progress by all graduate students in Cell & Molecular Biology (CM). All CM graduate students are encouraged to participate every semester, but receive two credits toward the degree only once, for CAS BI 583 or for CAS BI 584.
  • CAS BI 584: Seminar: Progress in Cell and Molecular Biology
    Undergraduate Prerequisites: Open to graduate students only.
    Facilitates presentation and discussion of research ideas, preliminary data, and research progress by all graduate students in Cell & Molecular Biology (CM). All CM graduate students are encouraged to participate every semester, but receive two credits toward the degree only once, for CAS BI 583 or for CAS BI 584.
  • CAS BI 591: Bio-Optical Oceanography
    Undergraduate Prerequisites: admission to the Marine Semester.
    This field- and lab-based course explores how the optically active constituents in seawater affect the in-water light field, and in turn, how field optics and remote sensing can facilitate the study of marine biogeochemistry, biological oceanography and water quality. Also offered as CAS ES 591.
  • CAS BI 593: Marine Physiology and Climate Change
    Undergraduate Prerequisites: CAS BI 108; or consent of the instructor, and admission to the Marine Semester.
    Explores the range of physiological responses marine organisms exhibit in response to climate change. Investigates phenotypic plasticity exhibited across different organisms and how this plasticity can influence an organism's resilience to its changing environment. Also offered as CAS ES 593.
  • CAS BI 594: Topics in Biology
    Examines contemporary topics in the biological sciences. This course may be repeated for credit if the topic is different. Pre-requisites vary with topic. Topic for Fall 2018, Section A1: Quantitative Approaches in Molecular Biology. Students learn and perform bioinformatics analysis on genome-wide and next generation sequencing of data. Pre-requisites: Familiarity with basic concepts in molecular biology, CAS BI 203 or equivalent, CAS MA 115 or equivalent. No prior programming knowledge is required. Students who have taken ENG BF 527 for credit cannot take this course for credit.